Affinity of FVIII-specific antibodies reveals major differences between neutralizing and nonneutralizing antibodies in humans

Blood

Volumn 125, Issue 7, 2015, Pages 1180-1188

  Hofbauer, Christoph J ^a   Whelan, Shawn F J ^a   Hirschler, Maria ^a   Allacher, Peter ^a   Horling, Frank M ^a   Lawo, John Philip ^a   Oldenburg, Johannes ^b   Tiede, Andreas ^c   Male, Christoph ^d   Windyga, Jerzy ^e   Greinacher, Andreas ^f   Knöbl, Paul N ^d   Schrenk, Gerald ^a   Koehn, Jadranka ^a   Scheiflinger, Friedrich ^a   Reipert, Birgit M ^a  

^a BAXTER BIOSCIENCE   (Austria)

^b Institute for Experimental Hematology and Transfusion Medicine   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e INSTITUTE OF HEMATOLOGY AND TRANSFUSION MEDICINE   (Poland)

^f UNIVERSITY MEDICINE GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8 ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT BLOOD CLOTTING FACTOR 8; AUTOANTIBODY; BLOOD CLOTTING FACTOR 8;

ADULT; AGED; ANTIBODY AFFINITY; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMOPHILIA A; HUMAN; MALE; PRIORITY JOURNAL; VERY ELDERLY; BLOOD; CASE CONTROL STUDY; IMMUNOLOGY; MIDDLE AGED; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, NEUTRALIZING; ANTIBODY AFFINITY; AUTOANTIBODIES; CASE-CONTROL STUDIES; FACTOR VIII; FEMALE; HEMOPHILIA A; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84923310176     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-09-598268     Document Type: Article

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