-
1
-
-
33745004785
-
Biomarkers of cardiovascular disease: molecular basis and practical considerations
-
Vasan RS. Biomarkers of cardiovascular disease: molecular basis and practical considerations. Circulation 2006;113:2335-2362.
-
(2006)
Circulation
, vol.113
, pp. 2335-2362
-
-
Vasan, R.S.1
-
2
-
-
0142200947
-
Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases
-
Hashimoto M, Rockenstein E, Crews L, Masliah E. Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases. Neuromol Med 2003;4:21-35.
-
(2003)
Neuromol Med
, vol.4
, pp. 21-35
-
-
Hashimoto, M.1
Rockenstein, E.2
Crews, L.3
Masliah, E.4
-
3
-
-
84885463056
-
Trimeric Tau is toxic to human neuronal cells at low nanomolar concentrations
-
Tian H, Davidowitz E, Lopez P, Emadi S, Moe J, Sierks M. Trimeric Tau is toxic to human neuronal cells at low nanomolar concentrations. Int J Cell Biol 2013;2013:9.
-
(2013)
Int J Cell Biol
, vol.2013
, pp. 9
-
-
Tian, H.1
Davidowitz, E.2
Lopez, P.3
Emadi, S.4
Moe, J.5
Sierks, M.6
-
4
-
-
84861185114
-
Nanobody specific for oligomeric beta-amyloid stabilizes nontoxic form
-
Kasturirangan S, Li L, Emadi S, Boddapati S, Schulz P, Sierks MR. Nanobody specific for oligomeric beta-amyloid stabilizes nontoxic form. Neurobiol Aging 2012;33:1320-1328.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1320-1328
-
-
Kasturirangan, S.1
Li, L.2
Emadi, S.3
Boddapati, S.4
Schulz, P.5
Sierks, M.R.6
-
5
-
-
56249092747
-
Anti-oligomeric Aβ single-chain variable domain antibody blocks Aβ-induced toxicity against human neuroblastoma cells
-
Zameer A, Kasturirangan S, Emadi S, Nimmagadda SV, Sierks MR. Anti-oligomeric Aβ single-chain variable domain antibody blocks Aβ-induced toxicity against human neuroblastoma cells. J Mol Biol 2008;384:917-928.
-
(2008)
J Mol Biol
, vol.384
, pp. 917-928
-
-
Zameer, A.1
Kasturirangan, S.2
Emadi, S.3
Nimmagadda, S.V.4
Sierks, M.R.5
-
6
-
-
84858052507
-
Bispecific tandem single chain antibody simultaneously inhibits β-secretase and promotes α-secretase processing of AβPP
-
Boddapati S, Levites Y, Suryadi V, Kasturirangan S, Sierks MR. Bispecific tandem single chain antibody simultaneously inhibits β-secretase and promotes α-secretase processing of AβPP. J Alzheimer Dis 2012;28:961-969.
-
(2012)
J Alzheimer Dis
, vol.28
, pp. 961-969
-
-
Boddapati, S.1
Levites, Y.2
Suryadi, V.3
Kasturirangan, S.4
Sierks, M.R.5
-
7
-
-
78650907799
-
Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP
-
Boddapati S, Levites Y, Sierks MR. Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP. J Mol Biol 2011;405:436-447.
-
(2011)
J Mol Biol
, vol.405
, pp. 436-447
-
-
Boddapati, S.1
Levites, Y.2
Sierks, M.R.3
-
9
-
-
84896859247
-
Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation
-
Xu P-X, Wang S-W, Yu X-L, Su YJ, Wang T, Zhou WW, Zhang H, Wang YJ, Liu RT . Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation. Behav Brain Res 2014;264:173-180.
-
(2014)
Behav Brain Res
, vol.264
, pp. 173-180
-
-
Xu, P.-X.1
Wang, S.-W.2
Yu, X.-L.3
Su, Y.J.4
Wang, T.5
Zhou, W.W.6
Zhang, H.7
Wang, Y.J.8
Liu, R.T.9
-
10
-
-
84882262363
-
Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples
-
Kasai T, Tokuda T, Taylor M, Kondo M, Mann DMA, Foulds PG, Nakagawa M, Allsop D . Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples. Neurosci Lett 2013;551:17-22.
-
(2013)
Neurosci Lett
, vol.551
, pp. 17-22
-
-
Kasai, T.1
Tokuda, T.2
Taylor, M.3
Kondo, M.4
Mann, D.M.A.5
Foulds, P.G.6
Nakagawa, M.7
Allsop, D.8
-
11
-
-
66449097646
-
Detecting morphologically distinct oligomeric forms of α-synuclein
-
Emadi S, Kasturirangan S, Wang MS, Schulz P, Sierks MR. Detecting morphologically distinct oligomeric forms of α-synuclein. J Biol Chem 2009;284:11048-11058.
-
(2009)
J Biol Chem
, vol.284
, pp. 11048-11058
-
-
Emadi, S.1
Kasturirangan, S.2
Wang, M.S.3
Schulz, P.4
Sierks, M.R.5
-
12
-
-
34147130637
-
Isolation of a human single chain antibody fragment against oligomeric α-synuclein that inhibits aggregation and prevents α-synuclein-induced toxicity
-
Emadi S, Barkhordarian H, Wang MS, Schulz P, Sierks MR. Isolation of a human single chain antibody fragment against oligomeric α-synuclein that inhibits aggregation and prevents α-synuclein-induced toxicity. J Mol Biol 2007;368:1132-1144.
-
(2007)
J Mol Biol
, vol.368
, pp. 1132-1144
-
-
Emadi, S.1
Barkhordarian, H.2
Wang, M.S.3
Schulz, P.4
Sierks, M.R.5
-
13
-
-
77951557863
-
Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model
-
Wang M, Boddapati S, Emadi S, Sierks M. Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model. BMC Neurosci 2010;11:57.
-
(2010)
BMC Neurosci
, vol.11
, pp. 57
-
-
Wang, M.1
Boddapati, S.2
Emadi, S.3
Sierks, M.4
-
14
-
-
84863719247
-
Virus-based piezoelectric energy generation
-
Lee BY, Zhang J, Zueger C, Chung WJ, Yoo SY, Wang E, Meyer J, Ramesh R, Lee SW . Virus-based piezoelectric energy generation. Nat Nano 2012;7:351-356.
-
(2012)
Nat Nano
, vol.7
, pp. 351-356
-
-
Lee, B.Y.1
Zhang, J.2
Zueger, C.3
Chung, W.J.4
Yoo, S.Y.5
Wang, E.6
Meyer, J.7
Ramesh, R.8
Lee, S.W.9
-
15
-
-
0032577317
-
The major coat protein of filamentous bacteriophage f1 specifically pairs in the bacterial cytoplasmic membrane
-
Haigh NG, Webster RE. The major coat protein of filamentous bacteriophage f1 specifically pairs in the bacterial cytoplasmic membrane. J Mol Biol 1998;279:19-29.
-
(1998)
J Mol Biol
, vol.279
, pp. 19-29
-
-
Haigh, N.G.1
Webster, R.E.2
-
16
-
-
0033605076
-
Effects of temperature and Y21M mutation on conformational heterogeneity of the major coat protein (pVIII) of filamentous bacteriophage fd
-
Tan WM, Jelinek R, Opella SJ, Malik P, Terry TD, Perham RN. Effects of temperature and Y21M mutation on conformational heterogeneity of the major coat protein (pVIII) of filamentous bacteriophage fd. J Mol Biol 1999;286:787-796.
-
(1999)
J Mol Biol
, vol.286
, pp. 787-796
-
-
Tan, W.M.1
Jelinek, R.2
Opella, S.J.3
Malik, P.4
Terry, T.D.5
Perham, R.N.6
-
17
-
-
0036605566
-
Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters
-
Rockenstein E, Mallory M, Hashimoto M, Song D, Shults CW, Lang I, Masliah E . Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters. J Neurosci Res 2002;68:568-578.
-
(2002)
J Neurosci Res
, vol.68
, pp. 568-578
-
-
Rockenstein, E.1
Mallory, M.2
Hashimoto, M.3
Song, D.4
Shults, C.W.5
Lang, I.6
Masliah, E.7
-
18
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, Laferla FM . Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction. Neuron 2003;39:409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
Laferla, F.M.10
-
19
-
-
0025181840
-
Zero-length crosslinking procedure with the use of active esters
-
Grabarek Z, Gergely J. Zero-length crosslinking procedure with the use of active esters. Anal Biochem 1990;185:131-135.
-
(1990)
Anal Biochem
, vol.185
, pp. 131-135
-
-
Grabarek, Z.1
Gergely, J.2
-
20
-
-
13444281916
-
Purification of filamentous bacteriophage for phage display using size-exclusion chromatography
-
198.
-
Zakharova MY, Kozyr AV, Ignatova AN, Vinnikov IA, Shemyakin IG, Kolesnikov AV. Purification of filamentous bacteriophage for phage display using size-exclusion chromatography. BioTechniques 2005;38:194, 196, 198.
-
(2005)
BioTechniques
, vol.38
, Issue.194
, pp. 196
-
-
Zakharova, M.Y.1
Kozyr, A.V.2
Ignatova, A.N.3
Vinnikov, I.A.4
Shemyakin, I.G.5
Kolesnikov, A.V.6
-
21
-
-
10344257196
-
A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed [alpha]-synuclein
-
Zhou C, Emadi S, Sierks MR, Messer A. A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed [alpha]-synuclein. Mol Ther 2004;10:1023-1031.
-
(2004)
Mol Ther
, vol.10
, pp. 1023-1031
-
-
Zhou, C.1
Emadi, S.2
Sierks, M.R.3
Messer, A.4
-
22
-
-
51349091340
-
Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display
-
Steiner D, Forrer P, Plückthun A. Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display. J Mol Biol 2008;382:1211-1227.
-
(2008)
J Mol Biol
, vol.382
, pp. 1211-1227
-
-
Steiner, D.1
Forrer, P.2
Plückthun, A.3
-
23
-
-
33746161571
-
Signal sequences directing cotranslational translocation expand the range of proteins amenable to phage display
-
Steiner D, Forrer P, Stumpp MT, Pluckthun A. Signal sequences directing cotranslational translocation expand the range of proteins amenable to phage display. Nat Biotech 2006;24:823-831.
-
(2006)
Nat Biotech
, vol.24
, pp. 823-831
-
-
Steiner, D.1
Forrer, P.2
Stumpp, M.T.3
Pluckthun, A.4
-
24
-
-
0035169340
-
A helper phage to improve single-chain antibody presentation in phage display
-
Rondot S, Koch J, Breitling F, Dubel S. A helper phage to improve single-chain antibody presentation in phage display. Nat Biotech 2001;19:75-78.
-
(2001)
Nat Biotech
, vol.19
, pp. 75-78
-
-
Rondot, S.1
Koch, J.2
Breitling, F.3
Dubel, S.4
-
25
-
-
0033538557
-
Removal of the conserved disulfide bridges from the scfv fragment of an antibody: effects on folding kinetics and aggregation
-
Ramm K, Gehrig P, Plückthun A. Removal of the conserved disulfide bridges from the scfv fragment of an antibody: effects on folding kinetics and aggregation. J Mol Biol 1999;290:535-546.
-
(1999)
J Mol Biol
, vol.290
, pp. 535-546
-
-
Ramm, K.1
Gehrig, P.2
Plückthun, A.3
-
26
-
-
84871324721
-
α-Synuclein and anti-α-synuclein antibodies in Parkinson's disease, atypical Parkinson syndromes, REM sleep behavior disorder, and healthy controls
-
Smith LM, Schiess MC, Coffey MP, Klaver AC, Loeffler DA. α-Synuclein and anti-α-synuclein antibodies in Parkinson's disease, atypical Parkinson syndromes, REM sleep behavior disorder, and healthy controls. PLoS ONE 2012;7:1-9.
-
(2012)
PLoS ONE
, vol.7
, pp. 1-9
-
-
Smith, L.M.1
Schiess, M.C.2
Coffey, M.P.3
Klaver, A.C.4
Loeffler, D.A.5
-
27
-
-
33845641270
-
On the influence of vector design on antibody phage display
-
Soltes G, Hust M, Ng KKY, Bansal A, Field J, Stewart DIH, Dübel S, Cha S, Wiersma EJ. On the influence of vector design on antibody phage display. J Biotechnol 2007;127:626-637.
-
(2007)
J Biotechnol
, vol.127
, pp. 626-637
-
-
Soltes, G.1
Hust, M.2
Ng, K.K.Y.3
Bansal, A.4
Field, J.5
Stewart, D.I.H.6
Dübel, S.7
Cha, S.8
Wiersma, E.J.9
-
28
-
-
33645833848
-
Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson's disease
-
El-Agnaf OMA, Salem SA, Paleologou KE, Curran MD, Gibson MJ, Court JA, Schlossmacher MG, Allsop D . Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson's disease. The FASEB J 2006;20:419-425.
-
(2006)
The FASEB J
, vol.20
, pp. 419-425
-
-
El-Agnaf, O.M.A.1
Salem, S.A.2
Paleologou, K.E.3
Curran, M.D.4
Gibson, M.J.5
Court, J.A.6
Schlossmacher, M.G.7
Allsop, D.8
-
29
-
-
84862916400
-
Elevated levels of α-synuclein oligomer in the cerebrospinal fluid of drug-naïve patients with Parkinson's disease
-
Park MJ, Cheon S-M, Bae H-R, Kim S-H, Kim JW. Elevated levels of α-synuclein oligomer in the cerebrospinal fluid of drug-naïve patients with Parkinson's disease. J Clin Neurol 2011;7:215-222.
-
(2011)
J Clin Neurol
, vol.7
, pp. 215-222
-
-
Park, M.J.1
Cheon, S.-M.2
Bae, H.-R.3
Kim, S.-H.4
Kim, J.W.5
-
30
-
-
54049143865
-
Multiplexed immunobead-based assay for detection of oral cancer protein biomarkers in saliva
-
Arellano-Garcia ME, Hu S, Wang J, Henson B, Zhou H, Chia D, Wong DT . Multiplexed immunobead-based assay for detection of oral cancer protein biomarkers in saliva. Oral Dis 2008;14:705-712.
-
(2008)
Oral Dis
, vol.14
, pp. 705-712
-
-
Arellano-Garcia, M.E.1
Hu, S.2
Wang, J.3
Henson, B.4
Zhou, H.5
Chia, D.6
Wong, D.T.7
-
31
-
-
47049096334
-
Expression of a Functional single-chain variable-fragment antibody against complement receptor 1 in Streptococcus gordonii
-
Knight JB, Halperin SA, West KA, Lee SF. Expression of a Functional single-chain variable-fragment antibody against complement receptor 1 in Streptococcus gordonii. Clin Vaccine Immunol 2008;15:925-931.
-
(2008)
Clin Vaccine Immunol
, vol.15
, pp. 925-931
-
-
Knight, J.B.1
Halperin, S.A.2
West, K.A.3
Lee, S.F.4
-
32
-
-
84878565584
-
Pentamerisation of a scFv directed against TRAIL receptor 2 increases its antitumour efficacy
-
Wang W, He W, Wang L, Zhang G, Gao B. Pentamerisation of a scFv directed against TRAIL receptor 2 increases its antitumour efficacy. Immunol Cell Biol 2013;91:360-367.
-
(2013)
Immunol Cell Biol
, vol.91
, pp. 360-367
-
-
Wang, W.1
He, W.2
Wang, L.3
Zhang, G.4
Gao, B.5
-
33
-
-
84859715471
-
scFv Antibody: principles and clinical application
-
Ahmad ZA, Yeap SK, Ali AM, Ho WY, Alitheen NBM, Hamid M. scFv Antibody: principles and clinical application. Clin Dev Immunol 2012;2012:15.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 15
-
-
Ahmad, Z.A.1
Yeap, S.K.2
Ali, A.M.3
Ho, W.Y.4
Alitheen, N.B.M.5
Hamid, M.6
|