Factors contributing to immunosuppression in the dairy cow during the periparturient period

Japanese Journal of Veterinary Research

Volumn 63, Issue , 2015, Pages S15-S24

  Ingvartsen, Klaus L ^a   Moyes, Kasey M ^b  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

Cow; Immunosuppression; Nutrition

Indexed keywords

ANIMAL; BOVINE; FEMALE; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; PERINATAL PERIOD; PHYSIOLOGY; PREGNANCY; VETERINARY;

ANIMALS; CATTLE; FEMALE; IMMUNOSUPPRESSION; PERIPARTUM PERIOD; PREGNANCY;

EID: 84923297616     PISSN: 00471917     EISSN: None     Source Type: Journal    
DOI: 10.14943/jjvr.63.suppl.s15     Document Type: Article

References (56)

1. Alipour, A., van Oostrom, A. J., Izraeljan, A., Verseyden, C., Collins, J. M., Frayn, K. N., Plokker, T. W., Elte, J. W. and Castro, C. M. 2008. Leukocyte activation by triglyceriderich lipoproteins. Arterioscler. Thromb. Vasc. Biol., 28: 792-797.
2. Barghouthi, S., Everett, K. D. and Speert, D. P. 1995. Nonopsonic phagocytosis of Pseudomonas aeruginosa requires facilitated transport of D-glucose by macrophages. J. Immunol., 154: 3420-3428.
3. Bastard, J. P., Maachi, M. C., Lagathu, Kim, M. J., Caron, M., Vidal, H., Capeau, J. and Feve, B. 2006. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur. Cytokine Netw., 17: 4-12.
4. Bauman, D. E. 2000. Regulation of nutrient partitioning during lactation: Homeostasis and homeorhesis revisited. pp. 311-328 in Ruminant Physiology: Digestion, Metabolism, Growth and Reproduction. P. B. Cronje, ed. CABI Publishing, New York, NY.
5. Bobe, G., Young, J. W. and Beitz, D. C. 2004. Invited review: pathology, etiology, prevention, and treatment of fatty liver in dairy cows. J. Dairy Sci., 87: 3105-3124.
6. Brassard, P., Larbi, A., Grenier, A., Frisch, F., Fortin, C., Carpentier, A. C. and Fulop, T. 2007. Modulation of T-cell signalling by nonesterified fatty acids. Prostaglandins Leukot. Essent. Fatty Acids, 77: 337-343.
7. Burton, J. L., Madsen, S. A., Chang, L. C., Weber, P. S., Buckham, K. R., van Dorp, R., Hickey, M. C. and Earley, B. 2005. Gene expression signatures in neutrophils exposed to glucocorticoids: a new paradigm to help explain “neutrophil dysfunction” in parturient dairy cows. Vet. Immunol. Immunopathol., 105: 197-219.
8. Cai, T. Q., Weston, P. G., Lund, L. A., Brodie, B., McKenna, D. J. and Wagner, W. C. 1994. Association between neutrophil functions and periparturient disorders in cows. Am. J. Vet. Res., 55: 934-943.
9. Cha, E., Bar, D., Hertl, J. A., Tauer, L. W., Bennett, G., Gonzalez, R. N., Schukken, Y. H., Welcome, F. L. and Grohn, Y. T. 2011. The cost and management of different types of clinical mastitis in dairy cows estimated by dynamic programming. J. Dairy Sci., 94: 4476-4487.
10. Chapinal, N., Carson, M., Duffield, T. F., Capel, M., Godden, S., Overton, M., Santos, J. E. and LeBlanc, S. J. 2011. The association of serum metabolites with clinical disease during the transition period. J. Dairy Sci., 94: 4897-4903.
11. Contreras, G. A. and Sordillo, L. M. 2011. Lipid mobilization and inflammatory responses during the transition period of dairy cows. Comp. Immunol. Microbiol. Infect. Dis., 34: 281-289.
12. de Vries, M. A., Alipour, A., Klop, B., van de Geijn, G. J., Janssen, H. W., Njo, T. L., van der Meulen, N., Rietveld, A. P., Liem, A. H., Westerman, E. M., de Herder, W. W. and Castro, C. M. 2015. Glucose-dependent leukocyte activation in patients with type 2 diabetes mellitus, familial combined hyperlipidemia and healthy controls. Metabolism, 64: 213-217.
13. Douglas, G. N., Rehage, J., Beaulieu, A. D., Bahaa, A. O. and Drackley, J. K. 2007. Prepartum nutrition alters fatty acid composition in plasma, adipose tissue, and liver lipids of periparturient dairy cows. J. Dairy Sci., 90: 2941-2959.
14. Drackley, J. K. 1999. Biology of dairy cows during the transition period: the final frontier? J. Dairy Sci., 82: 2259-2273.
15. Drackley, J. K., Donkin, S. S. and Reynolds, C. K. 2006. Major advances in fundamental dairy cattle nutrition. J. Dairy Sci., 89: 1324-1336.
16. Friggens, N. C., Berg, P., Theilgaard, P., Korsgaard, I. R., Ingvartsen, K. L., Lovendahl, P. and Jensen, J. 2007. Breed and parity effects on energy balance profiles through lactation: evidence of genetically driven body energy change. J. Dairy Sci., 90: 5291-5305.
17. Gamelli, R. L., Liu, H., He, L. K. and Hofmann, C. A. 1996. Augmentations of glucose uptake and glucose transporter-1 in macrophages following thermal injury and sepsis in mice. J. Leukoc. Biol., 59: 639-647.
18. Gearhart, M. A., Curtis, C. R., Erb, H. N., Smith, R. D., Sniffen, C. J., Chase, L. E. and Cooper, M. D. 1990. Relationship of changes in condition score to cow health in Holsteins. J. Dairy Sci., 73: 3132-3140.
19. Graugnard, D. E., Bionaz, M., Trevisi, E., Moyes, K. M., Salak-Johnson, J. L., Wallace, R. L., Drackley, J. K., Bertoni, G. and Loor, J. J. 2012a. Blood immunometabolic indices and polymorphonuclear neutrophil function in peripartum dairy cows are altered by level of dietary energy prepartum. J. Dairy Sci., 95: 1749-1758.
20. Graugnard, D. E., Bionaz, M., Trevisi, E., Moyes, K. M., Salak-Johnson, J. L., Wallace, R. L., Drackley, J. K., Bertoni, G. and Loor, J. J. 2012b. Blood immunometabolic indices and polymorphonuclear neutrophil function in peripartum dairy cows are altered by level of dietary energy prepartum. J. Dairy Sci., 95: 1749-1758.
21. Graugnard, D. E., Moyes, K. M., Trevisi, E., Khan, M. J., Keisler, D., Drackley, J. K., Bertoni, G. and Loor, J. J. 2013. Liver lipid content and inflammometabolic indices in peripartal dairy cows are altered in response to prepartal energy intake and postpartal intramammary inflammatory challenge. J. Dairy Sci., 96: 918-935.
22. Green, M. J., Green, L. E., Medley, G. F., Schukken, Y. H. and Bradley, A. J. 2002. Influence of dry period bacterial intramammary infection on clinical mastitis in dairy cows. J. Dairy Sci., 85: 2589-2599.
23. Grinberg, N., Elazar, S., Rosenshine, I. and Shpigel, N. Y. 2008. Beta-hydroxybutyrate abrogates formation of bovine neutrophil extracellular traps and bactericidal activity against mammary pathogenic Escherichia coli. Infect. Immun., 76: 2802-2807.
24. Grohn, Y. T., and Rajala-Schultz, P. J. 2000. Epidemiology of reproductive performance in dairy cows. Anim Reprod. Sci., 60-61: 605-614.
25. Ingvarsten, K. L., and Moyes, K. M. 2011. Nutrition, immune function and health of herbivores. Adv. Anim. Biosci., 2: 575.
26. Ingvartsen, K. L. 2006. Feeding-and management-related diseases in the transition cow, physiological adaptions around calving and strategies to reduce feeding-related diseases. Anim. Feed Sci Technol., 126: 175-213.
27. Ingvartsen, K. L., and Andersen, J. B. 2000. Integration of metabolism and intake regulation: a review focusing on periparturient animals. J. Dairy Sci., 83: 1573-1597.
28. Ingvartsen, K. L., Dewhurst, R. J. and Friggens, N. C. 2003. On the relationship between lactational performance and health: is it yield or metabolic imbalance that cause production diseases in dairy cattle? A position paper. Livest. Prod. Sci., 83: 277-308.
29. Ingvartsen, K. L., and Friggens, N. C. 2005. To what extent do variabilities in hormones, metabolites and energy intake explain variability in milk yield? Domest. Anim Endocrinol., 29: 294-304.
30. Ingvartsen, K. L., and Moyes, K. M. 2013. Nutrition, immune function and health of dairy cattle. Animal, 7 (Suppl 1): 112-122.
31. Janovick, N. A., Boisclair, Y. R. and Drackley, J. K. 2011. Prepartum dietary energy intake affects metabolism and health during the periparturient period in primiparous and multiparous Holstein cows. J. Dairy Sci., 94: 1385-1400.
32. Kehrli, M. E., Jr., J. F. Ridpath, and J. D. Neill. 2009. Immune suppression in cattle: Contributors and consequences. Pages 103-112 in Proceedings of the NMC 48th annual meeting, Charlotte, NC.
33. Lacetera, N., Scalia, D., Franci, O., Bernabucci, U., Ronchi, B. and Nardone, A. 2004. Short communication: effects of nonesterified fatty acids on lymphocyte function in dairy heifers. J. Dairy Sci., 87: 1012-1014.
34. Leblanc, S. 2010. Monitoring metabolic health of dairy cattle in the transition period. J. Reprod. Dev., 56 Suppl: S29-S35.
35. LeBlanc, S. J. 2012. Interactions of metabolism, inflammation, and reproductive tract health in the postpartum period in dairy cattle. Reprod. Domest. Anim., 47 Suppl 5: 18-30.
36. Lee, J. Y., and Hwang, D. H. 2006. The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors. Mol. Cells, 21: 174-185.
37. Lee, J. Y., Sohn, K. H., Rhee, S. H. and Hwang, D. 2001. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J. Biol. Chem., 276: 16683-16689.
38. Lee, J. Y., Zhao, L., Youn, H. S., Weatherill, A. R., Tapping, R., Feng, L., Lee, W. H., Fitzgerald, K. A. and Hwang, D. H. 2004. Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1. J. Biol. Chem., 279: 16971-16979.
39. Madsen, S. A., Weber, P. S. and Burton, J. L. 2002. Altered expression of cellular genes in neutrophils of periparturient dairy cows. Vet. Immunol. Immunopathol., 86: 159-175.
40. Martinez, N., Sinedino, L. D., Bisinotto, R. S., Ribeiro, E. S., Gomes, G. C., Lima, F. S., Greco, L. F., Risco, C. A., Galvao, K. N., Taylor-Rodriguez, D., Driver, J. P., Thatcher, W. W. and Santos, J. E. 2014. Effect of induced subclinical hypocalcemia on physiological responses and neutrophil function in dairy cows. J. Dairy Sci., 97: 874-887.
41. Moyes, K. M., Drackley, J. K., Morin, D. E. and Loor, J. J. 2010. Greater expression of TLR2, TLR4, and IL6 due to negative energy balance is associated with lower expression of HLA-DRA and HLA-A in bovine blood neutrophils after intramammary mastitis challenge with Streptococcus uberis. Funct. Integr. Genomics, 10: 53-61.
42. Moyes, K. M., Graugnard, D. E., Khan, M. J., Mukesh, M. and Loor J. J. 2014. Postpartal immunometabolic gene network expression and function in blood neutrophils are altered in response to prepartal energy intake and postpartal intramammary inflammatory challenge. J. Dairy Sci., 97: 2165-2177.
43. Moyes, K. M., Larsen, T. and Ingvartsen K. L. 2013. Generation of an index for physiological imbalance and its use as a predictor of disease in dairy cows during early lactation. J. Dairy Sci., 96: 2161-2170.
44. National Research Council. 2001. Nutrient Requirements of Dairy Cattle. National Academy Press, Washington, DC.
45. Newsholme, P., Curi, R., Gordon, S. and Newsholme, E. A. 1986. Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages. Biochem. J., 239: 121-125.
46. Newsholme, P., Gordon, S. and Newsholme, E. A. 1987. Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages. Biochem. J., 242: 631-636.
47. Newsholme, P., and Newsholme, E. A. 1989. Rates of utilization of glucose, glutamine and oleate and formation of end-products by mouse peritoneal macrophages in culture. Biochem. J., 261: 211-218.
48. Nielsen, H. M., Friggens, N. C., Lovendahl, P., Jensen, J. and Ingvartsen, K. L. 2003. Influence of breed, parity, and stage of lactation on lactational performance and relationship between body fatness and live weight. Livest. Prod. Sci., 79: 119-133.
49. Paape, M. J., Mehrzad, J., Zhao, X., Detilleux, J. C. and Burvenich, C. 2002. Defense of the bovine mammary gland by polymorphonuclear neutrophil leukocytes. J. Mammary Gland Biol. Neoplasia, 7: 109-121.
50. Pithon-Curi, T. C., De Melo, M. P. and Curi, R. 2004. Glucose and glutamine utilization by rat lymphocytes, monocytes and neutrophils in culture: a comparative study. Cell Biochem. Funct., 22: 321-326.
51. Scalia, D., Lacetera, N., Bernabucci, U., Demeyere, K., Duchateau, L. and Burvenich, C. 2006. In vitro effects of nonesterified fatty acids on bovine neutrophils oxidative burst and viability. J. Dairy Sci., 89: 147-154.
52. Schukken, Y. H., Gunther, J., Fitzpatrick, J., Fontaine, M. C., Goetze, L., Holst, O., Leigh, J., Petzl, W., Schuberth, H. J., Sipka, A., Smith, D. G., Quesnell, R., Watts, J., Yancey, R., Zerbe, H., Gurjar, A., Zadoks, R. N. and Seyfert, H. M. 2011. Host-response patterns of intramammary infections in dairy cows. Vet. Immunol. Immunopathol., 144: 270-289.
53. Sordillo, L. M., Contreras, G. A. and Aitken, S. L. 2009. Metabolic factors affecting the inflammatory response of periparturient dairy cows. Anim Health Res. Rev., 10: 53-63.
54. Tilg, H., and Moschen, A. R. 2008. Insulin resistance, inflammation, and non-alcoholic fatty liver disease. Trends Endocrinol. Metab., 19: 371-379.
55. van Knegsel, A. T., Van Den Brand, H., Dijkstra, J., Tamminga, S. and Kemp, B. 2005. Effect of dietary energy source on energy balance, production, metabolic disorders and reproduction in lactating dairy cattle. Reprod. Nutr. Dev., 45: 665-688.
56. Weber, P. S., Madsen-Bouterse, S. A., Rosa, G. J., Sipkovsky, S., Ren, X., Almeida, P. E., Kruska, R., Halgren, R. G., Barrick, J. L. and Burton, J. L. 2006. Analysis of the bovine neutrophil transcriptome during glucocorticoid treatment. Physiol. Genomics, 28: 97-112.