Effect of induced subclinical hypocalcemia on physiological responses and neutrophil function in dairy cows

Journal of Dairy Science

Volumn 97, Issue 2, 2014, Pages 874-887

  Martinez, N ^a   Sinedino, L D P ^a   Bisinotto, R S ^a   Ribeiro, E S ^a   Gomes, G C ^a   Lima, F S ^a   Greco, L F ^a   Risco, C A ^a   Galvao K N ^a   Taylor Rodriguez, D ^a   Driver, J P ^a   Thatcher, W W ^a   Santos, J E P ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Dairy cow; Immune function; Metabolism; Subclinical hypocalcemia

Indexed keywords

BACTERIA (MICROORGANISMS); BOS;

3 HYDROXYBUTYRIC ACID; CALCIUM; FATTY ACID; GLUCOSE; GLUCOSE BLOOD LEVEL; INSULIN;

ANIMAL; BLOOD; BOVINE; DRUG EFFECTS; FEMALE; GLUCOSE BLOOD LEVEL; HYPOCALCEMIA; LACTATION; METABOLISM; NEUTROPHIL; PHAGOCYTOSIS; PHYSIOLOGY; RANDOMIZATION; RESPIRATORY BURST; RUMINANT STOMACH;

3-HYDROXYBUTYRIC ACID; ANIMALS; BLOOD GLUCOSE; CALCIUM; CATTLE; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCOSE; HYPOCALCEMIA; INSULIN; LACTATION; NEUTROPHILS; PHAGOCYTOSIS; RANDOM ALLOCATION; RESPIRATORY BURST; RUMEN;

EID: 84892671087     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2013-7408     Document Type: Article

References (36)

1. Allen M.S. Effects of diet on short-term regulation of feed intake by lactating dairy cattle. J. Dairy Sci 2000, 83:1598-1624.
2. Bréchard S., Tschirhart E.J. Regulation of superoxide production in neutrophils: Role of calcium influx. J. Leukoc. Biol 2008, 84:1223-1237.
3. Burgos R.A., Conejeros I., Hidalgo M.A., Werling D., Hermosilla C. Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines. Vet. Immunol. Immunopathol 2011, 143:1-10.
4. Cohen M.S. Molecular events in the activation of human neutrophils for microbial killing. Clin. Infect. Dis 1994, 18:S170-S179.
5. Curtis C.R., Erb H.N., Sniffen C.J. Association of parturient hypocalcemia with eight periparturient disorders in Holstein cows. J. Am. Vet. Med. Assoc 1983, 183:559-561.
6. Daniel R.C.W. Motility of the rumen and abomasum during hypocalcaemia. Can. J. Comp. Med 1983, 47:276-280.
7. 2+ concentrations in polymorphonuclear leukocytes of postpartum dairy cows. Res. Vet. Sci 2003, 75:27-32.
8. Fukao T., Lopaschuk G.D., Mitchell G.A. Pathways and control of ketone body metabolism: On the fringe of lipid biochemistry. Prostaglandins Leukot. Essent. Fatty Acids 2004, 70:243-251.
9. Goff J.P. The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows. Vet. J 2008, 176:50-57.
10. 2EDTA on the feed intake and chewing activity of dairy cows. Vet. Res. Commun 2003, 27:193-205.
11. Hayirli A. The role of exogenous insulin in the complex of hepatic lipidosis and ketosis associated with insulin resistance phenomenon in postpartum dairy cattle. Vet. Res. Commun 2006, 30:749-774.
12. Horst R.L., Jorgensen N.A. Elevated plasma cortisol during induced and spontaneous hypocalcemia in ruminants. J. Dairy Sci 1982, 65:2332-2337.
13. Horst R.L.J.P., Goff, Reinhardt T.A. Adapting to the transition between gestation and lactation: Differences between rat, human and dairy cow. J. Mammary Gland Biol. Neoplasia 2005, 10:141-156.
14. Johnson M.M., Peters J.P. Technical note: An improved method to quantify nonesterified fatty acids in bovine plasma. J. Anim. Sci 1993, 71:753-756.
15. June C.H., Abe R., Rabinovitch P.S. Measurement of intracellular calcium ions by flow cytometry. Curr. Protoc. Cytom 2001, 9:8.1-8.19. http://dx.doi.org/10.1002/0471142956.cy0908s02.
16. Kaposi, A., G. Toldi, G. Meszaros, B. Szalay, G. Veress, and B. Vasarhelyi. 2012. Experimental conditions and mathematical analysis of kinetic measurements using flow cytometry- The FacsKin method, Ingrid Schmid, ed. Flow Cytometry-Recent Perspectives. Accessed Jun. 13, 2013. http://cdn.intechopen.com/pdfs/37435/InTech-Experimental_conditions_and_mathematical_analysis_of_kinetic_measurements_using_flow_cytometry_the_facskin_method.pdf.
17. Kimura K., Reinhardt T.A., Goff J.P. Parturition and hypocalcemia blunts calcium signals in immune cells of dairy cattle. J. Dairy Sci 2006, 89:2588-2595.
18. Larsen T., Møller G., Bellio R. Evaluation of clinical and clinical chemical parameters in periparturient cows. J. Dairy Sci 2001, 84:1749-1758.
19. Littledike E.T., Witzel D.A., Whipp S.C. Insulin: Evidence for inhibition of release in spontaneous hypocalcemia. Proc. Soc. Exp. Biol. Med. 1968, 129:135-139.
20. Martinez N., Lima F.S., Bisinotto R.S., Greco L.F., Ribeiro E.S., Maunsell F., Galvão K.N., Risco C.A., Santos J.E.P. Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease. J. Dairy Sci 2012, 95:7158-7172.
21. Massey C.D., Wang C., Donovan G.A., Beede D.K. Hypocalcemia at parturition as a risk factor for left displacement of the abomasums in dairy cows. J. Am. Vet. Med. Assoc 1993, 203:852-853.
22. Melendez P., Donovan G.A., Risco C.A., Goff J.P. Plasma mineral and energy metabolite concentrations in dairy cows fed an anionic prepartum diet that did or did not have retained fetal membranes after parturition. Am. J. Vet. Res 2004, 65:1071-1076.
23. Nutrient Requirements of Dairy Cattle 2001, Natl. Acad. Press, Washington, DC. 7th rev.
24. Paape M.J., Bannerman D.D., Xhao X., Lee J.W. The bovine neutrophil: Structure and function in blood and milk. Vet. Res 2003, 34:597-627.
25. Parekh A.B. Cell biology: Cracking the calcium entry code. Nature 2006, 441:163-165.
26. Quah B.J.C., Parish C.R. New and improved methods for measuring lymphocyte proliferation in vitro and in vivo using CFSE-like fluorescent dyes. J. Immunol. Methods 2012, 379:1-14.
27. Reinhardt T.A., Lippolis J.D., McCluskey B.J., Goff J.P., Horst R.L. Prevalence of subclinical hypocalcemia in dairy herds. Vet. J 2011, 188:122-124.
28. Ribeiro E.S., Lima F.S., Greco L.F., Bisinotto R.S., Monteiro A.P.A., Favoreto M., Ayres H., Marsola R.S., Martinez N., Thatcher W.W., Santos J.E.P. Prevalence of periparturient diseases and impacts on fertility of seasonally calving grazing dairy cows supplemented with concentrates. J. Dairy Sci 2013, 96:5682-5697.
29. Risco C.A., Reynolds J.P., Hird D. Uterine prolapse and hypocalcemia in dairy cows. J. Am. Vet. Med. Assoc 1984, 185:1517-1519.
30. Rorsman P., Braun M., Zhang Q. Regulation of calcium in pancreatic α- and β-cells in health and disease. Cell Calcium 2012, 51:300-308.
31. Saris N.E., Carafoli E. A historical review of cellular calcium handling, with emphasis on mitochondria. Biochemistry (Mosc.) 2005, 70:187-194.
32. Sordillo L.M., Raphael W. Significance of metabolic stress, lipid mobilization, and inflammation on transition cow disorders. Vet. Clin. North Am. Food Anim. Pract 2013, 29:267-278.
33. Valadares R.F.D., Broderick G.A., Valadares Filho S.C., Clayton M.K. Effect of replacing alfalfa silage with high moisture corn on ruminal protein synthesis estimated from excretion of total purine derivatives. J. Dairy Sci 1999, 82:2686-2696.
34. Van Soest P.J., Robertson J.B., Lewis B.A. Methods for dietary fiber, neutral detergent fiber and nonstarch polysaccharides in relation to animal nutrition. J. Dairy Sci 1991, 74:3583-3597.
35. Vig M., Kinet J.P. Calcium signaling in immune cells. Nat. Immunol 2009, 10:21-27.
36. Witzel D.A., Littledike E.T. Suppression of insulin secretion during induced hypocalcemia. Endocrinology 1973, 93:761-766.