Vitamin D Attenuates Cytokine-Induced Remodeling in Human Fetal Airway Smooth Muscle Cells

Journal of Cellular Physiology

Volumn 230, Issue 6, 2015, Pages 1189-1198

  Britt, Rodney D ^a   Faksh, Arij ^a   Vogel, Elizabeth R ^a   Thompson, Michael A ^a   Chu, Vivian ^a   Pandya, Hitesh C ^b   Amrani, Yassine ^b   Martin, Richard J ^c   Pabelick, Christina M ^a   Prakash, Y S ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; COLECALCIFEROL; COLLAGEN TYPE 1; COLLAGEN TYPE 3; FIBRONECTIN; GELATIN; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROCOLLAGEN; SMAD2 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VITAMIN D RECEPTOR; CYTOKINE;

AIRWAY REMODELING; AIRWAY SMOOTH MUSCLE CELL; ARTICLE; ASTHMA; CELL ISOLATION; CELL PROLIFERATION; CHILDHOOD DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FETUS; GENETIC TRANSFECTION; GESTATIONAL AGE; HEALTH CARE COST; HUMAN; HUMAN CELL; IN VITRO STUDY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING; ZYMOGRAPHY; DEFICIENCY; DRUG EFFECTS; METABOLISM; SMOOTH MUSCLE; VITAMIN D DEFICIENCY;

AIRWAY REMODELING; ASTHMA; CALCITRIOL; CELL PROLIFERATION; CYTOKINES; EXTRACELLULAR MATRIX; HUMANS; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN D DEFICIENCY;

EID: 84923280046     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24814     Document Type: Article

References (40)

1. Agrawal T, Gupta GK, Agrawal DK. 2012. Calcitriol decreases expression of importin alpha3 and attenuates RelA translocation in human bronchial smooth muscle cells. J Clin Immunol 32:1093-1103.
2. Anand SP, Selvaraj P. 2009. Effect of 1, 25 dihydroxyvitamin D(3) on matrix metalloproteinases MMP-7, MMP-9 and the inhibitor TIMP-1 in pulmonary tuberculosis. Clin Immunol 133:126-131.
3. Asher MI, Montefort S, Bjorksten B, Lai CK, Strachan DP, Weiland SK, Williams H. 2006. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 368:733-743.
4. Banerjee A, Damera G, Bhandare R, Gu S, Lopez-Boado Y, Panettieri R, Jr., Tliba O. 2008. Vitamin D and glucocorticoids differentially modulate chemokine expression in human airway smooth muscle cells. Br J Pharmacol 155:84-92.
5. Barbato A, Turato G, Baraldo S, Bazzan E, Calabrese F, Tura M, Zuin R, Beghe B, Maestrelli P, Fabbri LM, Saetta M. 2003. Airway inflammation in childhood asthma. Am J Respir Crit Care Med 168.
6. Bettoun DJ, Burris TP, Houck KA, Buck DW, 2nd, Stayrook KR, Khalifa B, Lu J, Chin WW, Nagpal S. 2003. Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation. Mol Endocrinol 17:2320-2328.
7. Black JL, Burgess JK, Johnson PR. 2003. Airway smooth muscle-its relationship to the extracellular matrix. Respir Physiol Neurobiol 137:339-346.
8. Brehm JM, Acosta-Perez E, Klei L, Roeder K, Barmada M, Boutaoui N, Forno E, Kelly R, Paul K, Sylvia J, Litonjua AA, Cabana M, Alvarez M, Colon-Semidey A, Canino G, Celedon JC. 2012. Vitamin D insufficiency and severe asthma exacerbations in Puerto Rican children. Am J Respir Crit Care Med 186:140-146.
9. Britt RD, Jr., Faksh A, Vogel E, Martin RJ, Pabelick CM, Prakash YS. 2013. Perinatal factors in neonatal and pediatric lung diseases. Expert Rev Respir Med 7:515-531.
10. Brown SD, Baxter KM, Stephenson ST, Esper AM, Brown LA, Fitzpatrick AM. 2012. Airway TGF-beta1 and oxidant stress in children with severe asthma: Association with airflow limitation. J Allergy Clin Immunol 129:388-396, 396 e1-8.
11. Burgess JK, Ceresa C, Johnson SR, Kanabar V, Moir LM, Nguyen TT, Oliver BG, Schuliga M, Ward J. 2009. Tissue and matrix influences on airway smooth muscle function. Pulm Pharmacol Ther 22:379-387.
12. Bush A, Menzies-Gow A. 2009. Phenotypic differences between pediatric and adult asthma. Proc Am Thorac Soc 6:712-719.
13. Camargo CA, Jr., Rifas-Shiman SL, Litonjua AA, Rich-Edwards JW, Weiss ST, Gold DR, Kleinman K, Gillman MW. 2007. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr 85:788-795.
14. Choi CJ, Seo M, Choi WS, Kim KS, Youn SA, Lindsey T, Choi YJ, Kim CM. 2013. Relationship between serum 25-hydroxyvitamin D and lung function among Korean adults in Korea National Health and Nutrition Examination Survey (KNHANES), 2008-2010. J Clin Endocrinol Metab 98:1703-1710.
15. Crane-Godreau MA, Black CC, Giustini AJ, Dechen T, Ryu J, Jukosky JA, Lee HK, Bessette K, Ratcliffe NR, Hoopes PJ, Fiering S, Kelly JA, Leiter JC. 2013. Modeling the influence of vitamin D deficiency on cigarette smoke-induced emphysema. Front Physiol 4:132.
16. Damera G, Fogle HW, Lim P, Goncharova EA, Zhao H, Banerjee A, Tliba O, Krymskaya VP, Panettieri RA, Jr. 2009. Vitamin D inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1. Br J Pharmacol 158:1429-1441.
17. Deeb KK, Trump DL, Johnson CS. 2007. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer 7:684-700.
18. Devereux G, Litonjua AA, Turner SW, Craig LC, McNeill G, Martindale S, Helms PJ, Seaton A, Weiss ST. 2007. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr 85:853-859.
19. Doherty T, Broide D. 2007. Cytokines and growth factors in airway remodeling in asthma. Curr Opin Immunol 19:676-680.
20. Freishtat RJ, Iqbal SF, Pillai DK, Klein CJ, Ryan LM, Benton AS, Teach SJ. 2010. High prevalence of vitamin D deficiency among inner-city African American youth with asthma in Washington. DC. J Pediatr 156:948-952.
21. Gaultier C, Harf A, Balmain N, Cuisinier-Gleizes P, Mathieu H. 1984. Lung mechanics in rachitic rats. Am Rev Respir Dis 130:1108-1110.
22. Gorman S, Tan DH, Lambert MJ, Scott NM, Judge MA, Hart PH. 2012. Vitamin D(3) deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway disease. Pediatr Allergy Immunol 23:83-87.
23. Gupta A, Sjoukes A, Richards D, Banya W, Hawrylowicz C, Bush A, Saglani S. 2011. Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma. Am J Respir Crit Care Med 184:1342-1349.
24. Hartman WR, Smelter DF, Sathish V, Karass M, Kim S, Aravamudan B, Thompson MA, Amrani Y, Pandya HC, Martin RJ, Prakash YS, Pabelick CM. 2012. Oxygen dose responsiveness of human fetal airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 303:L711-L719.
25. Labrie M, St-Pierre Y. 2013. Epigenetic regulation of mmp-9 gene expression. Cell Mol Life Sci 70:3109-3124.
26. Li F, Peng M, Jiang L, Sun Q, Zhang K, Lian F, Litonjua AA, Gao J, Gao X. 2011. Vitamin D deficiency is associated with decreased lung function in Chinese adults with asthma. Respiration 81:469-475.
27. Malmstrom K, Pelkonen AS, Makela MJ. 2013. Remodeling, inflammation and airway responsiveness in early childhood asthma. Curr Opin Allergy Clin Immunol 13:203-210.
28. McKleroy W, Lee TH, Atabai K. 2013. Always cleave up your mess: Targeting collagen degradation to treat tissue fibrosis. Am J Physiol Lung Cell Mol Physiol 304:L709-L721.
29. Palmer LJ, Rye PJ, Gibson NA, Burton PR, Landau LI, Lesouef PN. 2001. Airway responsiveness in early infancy predicts asthma, lung function, and respiratory symptoms by school age. Am J Respir Crit Care Med 163:37-42.
30. Pandya HC, Snetkov VA, Twort CH, Ward JP, Hirst SJ. 2002. Oxygen regulates mitogen-stimulated proliferation of fetal human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 283:L1220-L1230.
31. Pera T, Gosens R, Lesterhuis AH, Sami R, van der Toorn M, Zaagsma J, Meurs H. 2010. Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype. Respir Res 11:48.
32. Prufer K, Barsony J. 2002. Retinoid X receptor dominates the nuclear import and export of the unliganded vitamin D receptor. Mol Endocrinol 16:1738-1751.
33. Puthothu B, Bierbaum S, Kopp MV, Forster J, Heinze J, Weckmann M, Krueger M, Heinzmann A. 2009. Association of TNF-alpha with severe respiratory syncytial virus infection and bronchial asthma. Pediatr Allergy Immunol 20:157-163.
34. Saglani S, Malmstrom K, Pelkonen AS, Malmberg LP, Lindahl H, Kajosaari M, Turpeinen M, Rogers AV, Payne DN, Bush A, Haahtela T, Makela MJ, Jeffery PK. 2005. Airway remodeling and inflammation in symptomatic infants with reversible airflow obstruction. Am J Respir Crit Care Med 171:722-727.
35. Song Y, Qi H, Wu C. 2007. Effect of 1, 25-(OH) 2D3 (a vitamin D analogue) on passively sensitized human airway smooth muscle cells. Respirology 12:486-494.
36. Sundar IK, Hwang JW, Wu S, Sun J, Rahman I. 2011. Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation. Biochem Biophys Res Commun 406:127-133.
37. Sutherland ER, Goleva E, Jackson LP, Stevens AD, Leung DY. 2010. Vitamin D levels, lung function, and steroid response in adult asthma. Am J Respir Crit Care Med 181:699-704.
38. Theiss AL, Simmons JG, Jobin C, Lund PK. 2005. Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2. J Biol Chem 280:36099-36109.
39. Visse R, Nagase H. 2003. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92:827-839.
40. Zosky GR, Hart PH, Whitehouse AJ, Kusel MM, Ang W, Foong RE, Chen L, Holt PG, Sly PD, Hall GL. 2014. Vitamin D deficiency at 16-20 weeks gestation is associated with impaired lung function and asthma at 6 years of age. Ann Am Thorac Soc 11:571-577.