Sildenafil ameliorates long term peripheral neuropathy in type II diabetic mice

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Wang, Lei ^a   Chopp, Michael ^a,b   Szalad, Alexandra ^a   Jia, Longfei ^a   Lu, Xuerong ^a   Lu, Mei ^a   Zhang, Li ^a   Zhang, Yi ^a   Zhang, Ruilan ^a   Zhang, Zheng Gang ^a  

^a HENRY FORD HOSPITAL   (United States)

^b OAKLAND UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; GLUCOSE; HEMOGLOBIN A1C; NEUTRALIZING ANTIBODY; PLACEBO; SILDENAFIL; TRIACYLGLYCEROL; TEK PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; CAPILLARY TUBE; CELL CULTURE; CELL DENSITY; CELLULAR DISTRIBUTION; CHRONIC DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DERMAL MICROVASCULAR ENDOTHELIAL CELL; DIABETIC NEUROPATHY; DISEASE DURATION; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG TARGETING; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; MALE; MOTOR NERVE CONDUCTION; MOUSE; MYELINATED NERVE; NERVE CELL CULTURE; NERVE FIBER; NERVE FIBER GROWTH; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PERIPHERAL NEUROPATHY; PROTEIN EXPRESSION; SCIATIC NERVE; SENSORIMOTOR FUNCTION; SENSORY NERVE CONDUCTION; SKIN NERVE; SPINAL GANGLION; STIMULUS RESPONSE; THERMAL STIMULATION; TISSUE DISTRIBUTION; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; COMPLICATION; CONVALESCENCE; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PERIPHERAL NERVOUS SYSTEM DISEASES; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

MUS;

ANGIOPOIETIN-1; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; MALE; MICE; PERIPHERAL NERVOUS SYSTEM DISEASES; RECEPTOR, TIE-2; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION; SILDENAFIL CITRATE; TREATMENT OUTCOME;

EID: 84923275772     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118134     Document Type: Article

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