Increased interleukin-6 and high-sensitivity C-reactive protein levels in pediatric epilepsy patients with frequent, refractory generalized motor seizures

Seizure

Volumn 25, Issue , 2015, Pages 136-140

  Ishikawa, Nobustune ^a   Kobayashi, Yoshiyuki ^a   Fujii, Yuji ^a   Kobayashi, Masao ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Chronic inflammation; Generalized motor seizure; High sensitivity CRP; IL 6; Intractable epilepsy; PTX3

Indexed keywords

ANTICONVULSIVE AGENT; C REACTIVE PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PENTRAXIN 3; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL MARKER; IL1B PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; SERUM AMYLOID P;

ARTICLE; BODY MASS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; FEMALE; GENERALIZED EPILEPSY; GENERALIZED MOTOR SEIZURE; HUMAN; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; BLOOD; EPILEPSY; METABOLISM; SEIZURE;

BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; SEIZURES; SERUM AMYLOID P-COMPONENT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84923254658     PISSN: 10591311     EISSN: 15322688     Source Type: Journal    
DOI: 10.1016/j.seizure.2014.10.007     Document Type: Article

References (45)

1. M.A. Gomez-Marcos, J.I. Recio-Rodriguez, M.C. Patino-Alonso, C. Agudo-Conde, L. Gomez-Sanchez, and E. Rodriguez-Sanchez Relationships between high-sensitive C-reactive protein and markers of arterial stiffness in hypertensive patients. Differences by sex BMC Cardiovasc Disord 12 2012 37
2. M. Assadpour Piranfar The correlation between high-sensitivity C-reactive protein (HSCRP) serum levels and severity of coronary atherosclerosis Int Cardiovasc Res J 8 2014 6 8
3. Z.C. Deng, P. Zhao, C. Cao, S.F. Sun, F. Zhao, and C.Y. Lu C-Reactive protein as a prognostic marker in chronic obstructive pulmonary disease Exp Ther Med 7 2014 443 446
4. A. Firouzjahi, M. Monadi, F. Karimpoor, B. Heidari, Y. Dankoob, and K. Hajian-Tilaki Serum C-reactive protein level and distribution in chronic obstructive pulmonary disease versus healthy controls: a case-control study from Iran Inflammation 36 2013 1122 1128
5. I.U. Song, S.W. Chung, J.S. Kim, and K.S. Lee Association between high-sensitivity C-reactive protein and risk of early idiopathic Parkinson's disease Neurol Sci 32 2011 31 34
6. D. Impellizzeri, E. Esposito, J. Attley, and S. Cuzzocrea Targeting inflammation: new therapeutic approaches in chronic kidney disease (CKD) Pharmacol Res 81 2014 91 102
7. R.L. VanGilder, D.M. Davidov, K.R. Stinehart, J.D. Huber, R.C. Turner, and K.S. Wilson C-reactive protein and long-term ischemic stroke prognosis J Clin Neurosci 21 2014 547 553
8. G. Liuzzo, L.M. Biasucci, J.R. Gallimore, R.L. Grillo, A.G. Rebuzzi, and M.B. Pepys The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina N Engl J Med 331 1994 417 424
9. P.M. Ridker High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease Circulation 103 2001 1813 1818
10. M. Lech, C. Rommele, and H.J. Anders Pentraxins in nephrology: C-reactive protein, serum amyloid P and pentraxin-3 Nephrol Dial Transplant 28 2013 803 811
11. W. Ge, H.L. Wang, and R.P. Sun Pentraxin 3 as a novel early biomarker for the prediction of Henoch-Schonlein purpura nephritis in children Eur J Pediatr 173 2014 213 218
12. S. Padeh, N. Farzam, G. Chayen, M. Gerstein, and Y. Berkun Pentraxin 3 is a marker of early joint inflammation in patients with juvenile idiopathic arthritis Immunol Res 56 2013 444 450
13. A. Vezzani, and T. Granata Brain inflammation in epilepsy: experimental and clinical evidence Epilepsia 46 2005 1724 1743
14. A. Vezzani, E. Aronica, A. Mazarati, and Q.J. Pittman Epilepsy and brain inflammation Exp Neurol 244 2013 11 21
15. A. Vezzani, A. Friedman, and R.J. Dingledine The role of inflammation in epileptogenesis Neuropharmacology 69 2013 16 24
16. I.F. Uludag, S. Bilgin, Y. Zorlu, G. Tuna, and G. Kirkali Interleukin-6, interleukin-1 beta and interleukin-1 receptor antagonist levels in epileptic seizures Seizure 22 2013 457 461
17. J. Peltola, J. Palmio, L. Korhonen, J. Suhonen, A. Miettinen, and M. Hurme Interleukin-6 and interleukin-1 receptor antagonist in cerebrospinal fluid from patients with recent tonic-clonic seizures Epilepsy Res 41 2000 205 211
18. G. Yamanaka, H. Kawashima, S. Oana, Y. Ishida, T. Miyajima, and Y. Kashiwagi Increased level of serum interleukin-1 receptor antagonist subsequent to resolution of clinical symptoms in patients with West syndrome J Neurol Sci 298 2010 106 109
19. T. Shiihara, M. Miyashita, M. Yoshizumi, M. Watanabe, Y. Yamada, and M. Kato Peripheral lymphocyte subset and serum cytokine profiles of patients with West syndrome Brain Dev 32 2010 695 702
20. J. Peltola, M. Hurme, A. Miettinen, and T. Keranen Elevated levels of interleukin-6 may occur in cerebrospinal fluid from patients with recent epileptic seizures Epilepsy Res 31 1998 129 133
21. J. Peltola, J. Laaksonen, A.M. Haapala, M. Hurme, S. Rainesalo, and T. Keranen Indicators of inflammation after recent tonic-clonic epileptic seizures correlate with plasma interleukin-6 levels Seizure 11 2002 44 46
22. T. Alapirtti, M. Waris, M. Fallah, M. Soilu-Hanninen, R. Makinen, and E. Kharazmi C-reactive protein and seizures in focal epilepsy: a video-electroencephalographic study Epilepsia 53 2012 790 796
23. T. Ravizza, D. Moneta, B. Bottazzi, G. Peri, C. Garlanda, and E. Hirsch Dynamic induction of the long pentraxin PTX3 in the CNS after limbic seizures: evidence for a protective role in seizure-induced neurodegeneration Neuroscience 105 2001 43 53
24. J.C. Neill, Z. Liu, M. Sarkisian, P. Tandon, Y. Yang, and C.E. Stafstrom Recurrent seizures in immature rats: effect on auditory and visual discrimination Brain Res Dev Brain Res 95 1996 283 292
25. Z. Liu, Y. Yang, D.C. Silveira, M.R. Sarkisian, P. Tandon, and L.T. Huang Consequences of recurrent seizures during early brain development Neuroscience 92 1999 1443 1454
26. Y.H. Chen, T.T. Kuo, M.T. Chu, H.I. Ma, Y.H. Chiang, and E.Y. Huang Postnatal systemic inflammation exacerbates impairment of hippocampal synaptic plasticity in an animal seizure model Neuroimmunomodulation 20 2013 223 232
27. A. Rojas, J. Jiang, T. Ganesh, M.S. Yang, N. Lelutiu, and P. Gueorguieva Cyclooxygenase-2 in epilepsy Epilepsia 55 2014 17 25
28. A. Friedman, and R. Dingledine Molecular cascades that mediate the influence of inflammation on epilepsy Epilepsia 52 Suppl. 3 2011 33 39
29. G. Li, S. Bauer, M. Nowak, B. Norwood, B. Tackenberg, and F. Rosenow Cytokines and epilepsy Seizure 20 2011 249 256
30. T. Alapirtti, S. Rinta, J. Hulkkonen, R. Makinen, T. Keranen, and J. Peltola Interleukin-6, interleukin-1 receptor antagonist and interleukin-1beta production in patients with focal epilepsy: a video-EEG study J Neurol Sci 280 2009 94 97
31. J.E. Volanakis Human C-reactive protein: expression, structure, and function Mol Immunol 38 2001 189 197
32. A. Wasilewska, E. Tenderenda, K. Taranta-Janusz, and W. Zoch-Zwierz High-sensitivity C-reactive protein and mean platelet volume in paediatric hypertension Pediatr Nephrol 25 2010 1519 1527
33. G. Almroth, J. Lonn, F. Uhlin, F. Nayeri, L. Brudin, and B. Andersson Fibroblast growth factor 23, hepatocyte growth factor, interleukin-6, high-sensitivity C-reactive protein and soluble urokinase plasminogen activator receptor. Inflammation markers in chronic haemodialysis patients' Scand J Immunol 78 2013 285 290
34. M.J. Engelhart, M.I. Geerlings, J. Meijer, A. Kiliaan, A. Ruitenberg, and J.C. van Swieten Inflammatory proteins in plasma and the risk of dementia: the Rotterdam study Arch Neurol 61 2004 668 672
35. F. Bonacina, A. Baragetti, A.L. Catapano, and G.D. Norata Long pentraxin 3: experimental and clinical relevance in cardiovascular diseases Mediat Inflamm 2013 2013 725102
36. A. Mantovani, S. Valentino, S. Gentile, A. Inforzato, B. Bottazzi, and C. Garlanda The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules Ann N Y Acad Sci 1285 2013 1 14
37. N.S. Jenny, R.S. Blumenthal, R.A. Kronmal, J.I. Rotter, D.S. Siscovick, and B.M. Psaty Associations of pentraxin 3 with cardiovascular disease: the multi-ethnic study of atherosclerosis J Thromb Haemost 12 2014 999 1005
38. S. Kimura, H. Inagaki, G. Haraguchi, T. Sugiyama, T. Miyazaki, and Y. Hatano Relationships of elevated systemic pentraxin-3 levels with high-risk coronary plaque components and impaired myocardial perfusion after percutaneous coronary intervention in patients with ST-elevation acute myocardial infarction Circ J 78 2013 159 169
39. V. Bevelacqua, M. Libra, M.C. Mazzarino, P. Gangemi, G. Nicotra, and S. Curatolo Long pentraxin 3: a marker of inflammation in untreated psoriatic patients Int J Mol Med 18 2006 415 423
40. T. Yasunaga, S. Ikeda, S. Koga, T. Nakata, T. Yoshida, and N. Masuda Plasma pentraxin 3 is a more potent predictor of endothelial dysfunction than high-sensitive C-reactive protein Int Heart J 55 2014 160 164
41. T.Y. Tan, C.H. Lu, H.Y. Chuang, T.K. Lin, C.W. Liou, and W.N. Chang Long-term antiepileptic drug therapy contributes to the acceleration of atherosclerosis Epilepsia 50 2009 1579 1586
42. A.W. Yuen, G.S. Bell, J.L. Peacock, M.M. Koepp, P.N. Patsalos, and J.W. Sander Effects of AEDs on biomarkers in people with epilepsy: CRP, HbA1c and eGFR Epilepsy Res 91 2010 187 192
43. S. Mintzer, C.T. Skidmore, C.J. Abidin, M.C. Morales, I. Chervoneva, and D.M. Capuzzi Effects of antiepileptic drugs on lipids, homocysteine, and C-reactive protein Ann Neurol 65 2009 448 456
44. L. Librizzi, F. Noe, A. Vezzani, M. de Curtis, and T. Ravizza Seizure-induced brain-borne inflammation sustains seizure recurrence and blood-brain barrier damage Ann Neurol 72 2012 82 90
45. Y.S. Kwon, E. Pineda, S. Auvin, D. Shin, A. Mazarati, and R. Sankar Neuroprotective and antiepileptogenic effects of combination of anti-inflammatory drugs in the immature brain J Neuroinflamm 10 2013 30