Elevated levels of interleukin-6 may occur in cerebrospinal fluid from patients with recent epileptic seizures

Epilepsy Research

Volumn 31, Issue 2, 1998, Pages 129-133

  Peltola, Jukka ^a   Hurme, Mikko ^b   Miettinen, Ari ^a   Keränen, Tapani ^a  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Cerebrospinal fluid; Cytokines; Epilepsy; IL 6

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPILEPSY; EPILEPTOGENESIS; HUMAN; IMMUNE SYSTEM; IMMUNOSTIMULATION; PRIORITY JOURNAL; SEIZURE; TONIC CLONIC SEIZURE;

ADOLESCENT; ADULT; C-REACTIVE PROTEIN; FEMALE; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; SEIZURES; TIME FACTORS;

EID: 0031830922     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(98)00024-2     Document Type: Article

References (12)

1. Bruce A.J., Boling W., Kindy M.S., Peschon J., Kraemer P.H., Carpenter M.K., Holtsberg F.W., Mattson M.P. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nature Med. 2:1996;788-794.
2. De Bock F., Dornand J., Rondouin G. Release of TNFα in the rat hippocampus following epileptic seizures and excitotoxic neuronal damage. NeuroReport. 7:1996;1125-1129.
3. Devinsky O., Nadi S., Theodore W.H., Porter R.J. Cerebrospinal fluid pleocytosis following simple, complex partial, and generalized tonic-clonic seizures. Ann Neurol. 23:1988;402-403.
4. Hopkins S.J., Rothwell N.J. Cytokines and the nervous system I: expression and recognition. Trends Neurosci. 18:1995;83-88.
5. Iivanainen M., Hietala J., Malkamäki M., Waltimo O., Valtonen V.V. An association between epileptic seizures and increased serum bacterial antibody levels. Epilepsia. 24:1983;584-587.
6. McKenzie, S.B., 1996. Nonmalignant granulocyte and monocyte disorders. In: McKenzie, S.B. (Ed.), Textbook of Hematology. Williams and Wilkins, Baltimore, pp. 275-295.
7. Minami M., Kuraishi Y., Satoh M. Effects of kainic acid on messenger RNA levels of IL-1α, IL-6, TNFα and LIF in the rat brain. Biochem Biophys Res Commun. 176:1991;593-598.
8. Minami M., Kuraishi Y., Yamaguchi T., Nakai S., Hirai Y., Satoh M. Convulsants induce interleukin-1β messenger RNA in rat brain. Biochem Biophys Res Commun. 171:1990;832-837.
9. Prasad A.V., Pilcher W.H., Joseph S.A. Nuclear factor-kappa B in rat brain: enhanced DNA-binding activity following convulsant-induced seizures. Neurosci Lett. 170:1994;145-148.
10. Ruth R.E. Increased cerebrovascular permeability to protein during systemic kainic acid seizures. Epilepsia. 25:1984;259-268.
11. St. Pierre, B.A., Merrill, J.E., Dopp, J.M., 1996. Effects of cytokines on CNS cells: glia. In: Ransohoff, R.M., Benveniste, E.N. (Eds.), Cytokines and the CNS. CRC Press, Boca Raton, FL, pp. 151-168.
12. Yong, V.W., 1996. Cytokines, astrogliosis, and neurotrophism following CNS trauma. In: Ransohoff, R.M., Benveniste, E.N. (Eds.), Cytokines and the CNS. CRC Press, Boca Raton, FL, pp. 309-327.