Paternal heterochromatin formation in human embryos is H3K9/HP1 directed and primed by sperm-derived histone modifications

Nature Communications

Volumn 5, Issue , 2014, Pages

  Van De Werken, Christine ^a   Van Der Heijden, Godfried W ^a   Eleveld, Cindy ^a   Teeuwssen, Miriam ^a   Albert, Mareike ^b,d   Baarends, Willy M ^a   Laven, Joop S E ^a   Peters, Antoine H F M ^b,c   Baart, Esther B ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROCHROMATIN PROTEIN 1; HISTONE H4; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; REPETITIVE DNA; SATELLITE DNA; HETEROCHROMATIN; HETEROCHROMATIN-SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP-1; HISTONE; NONHISTONE PROTEIN;

EMBRYO; GENETIC ANALYSIS; GENOME; HERITABILITY; PARENTAL CARE; PROTEIN; SPERM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANONICAL ANALYSIS; CELL CYCLE G2 PHASE; CHROMOSOME BAND; CONSTITUTIVE HETEROCHROMATIN; CONTROLLED STUDY; DNA CONTENT; DNA REPLICATION; EMBRYO; EPIGENETICS; FEMALE; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IMMUNODETECTION; IMMUNOFLUORESCENCE; INHERITANCE; MOUSE; NONHUMAN; OOCYTE; PREIMPLANTATION EMBRYO; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERM; ANIMAL; ANIMAL EMBRYO; BLASTOCYST; CHEMISTRY; CYTOLOGY; FERTILIZATION; FERTILIZATION IN VITRO; GENE EXPRESSION REGULATION; GENETICS; HETEROCHROMATIN; MALE; METABOLISM; OOCYTE DEVELOPMENT; SPECIES DIFFERENCE; SPERMATOGENESIS; SPERMATOZOON; ULTRASTRUCTURE; ZYGOTE;

ANIMALS; BLASTOCYST; CHROMOSOMAL PROTEINS, NON-HISTONE; EMBRYO, MAMMALIAN; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HETEROCHROMATIN; HISTONES; HUMANS; INHERITANCE PATTERNS; MALE; MICE; OOCYTES; OOGENESIS; POLYCOMB-GROUP PROTEINS; SPECIES SPECIFICITY; SPERMATOGENESIS; SPERMATOZOA; ZYGOTE;

EID: 84923247667     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6868     Document Type: Article

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