TWIST1 silencing enhances in vitro and in vivo osteogenic differentiation of human adipose-derived stem cells by triggering activation of BMP-ERK/FGF signaling and TAZ upregulation

Stem Cells

Volumn 33, Issue 3, 2015, Pages 833-847

  Quarto, Natalina ^a,b   Senarath Yapa, Kshemendra ^a   Renda, Andrea ^b   Longaker, Michael T ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Activation; hASCs; Osteogenesis; Signaling; Silencing; TAZ; TWIST1; Upregulation

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; COMPLEMENT FACTOR D; FIBROBLAST GROWTH FACTOR RECEPTOR 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PROTEIN; SHORT HAIRPIN RNA; TAZ PROTEIN; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST1; UNCLASSIFIED DRUG; BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; NUCLEAR PROTEIN; TAZ PROTEIN, HUMAN; TAZ PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TWIST1 PROTEIN, HUMAN; TWIST1 PROTEIN, MOUSE;

ADIPOSE DERIVED STEM CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF QUANTITATION; MALE; MESENCHYMAL STEM CELL; MINERALIZATION; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOGENIC GIFFERENTIATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGENERATIVE ABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUDE MOUSE; PHYSIOLOGY; PROCEDURES; TISSUE ENGINEERING;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; FIBROBLAST GROWTH FACTORS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, NUDE; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TRANSCRIPTION FACTORS; TRANSFECTION; TWIST TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84923228668     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1907     Document Type: Article

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