Upconversion nanoparticles: A versatile solution to multiscale biological imaging

Bioconjugate Chemistry

Volumn 26, Issue 2, 2015, Pages 166-175

  Wu, Xiang ^a,b   Chen, Guanying ^c,d   Shen, Jie ^a   Li, Zhanjun ^a   Zhang, Yuanwei ^a   Han, Gang ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^c HARBIN INSTITUTE OF TECHNOLOGY   (China)

^d STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DELIVERY; INFRARED DEVICES; MEDICAL IMAGING; NANOPARTICLES;

ANTI-STOKES; BIOLOGICAL IMAGING; BIOMEDICAL IMAGING; CONTRAST AGENT; EXCITATION RADIATION; IMAGING CONTRAST; LONG WAVELENGTH; NEAR-INFRARED EXCITATION; SHORT-WAVELENGTH EMISSIONS; UPCONVERSION NANOPARTICLES;

NANOSTRUCTURED MATERIALS;

FLUORESCENT DYE; UPCONVERSION NANOPARTICLE; LANTHANIDE; NANOPARTICLE;

BIOASSAY; EXCITATION; FLUORESCENCE IMAGING; HUMAN; MOLECULAR IMAGING; NONHUMAN; PHOTOCHEMISTRY; PHOTODYNAMIC THERAPY; PHOTOREACTIVITY; REVIEW; SYNTHESIS; ANIMAL; NEOPLASMS; PHOTOCHEMOTHERAPY; PROCEDURES; ULTRASTRUCTURE;

ANIMALS; FLUORESCENT DYES; HUMANS; LANTHANOID SERIES ELEMENTS; NANOPARTICLES; NEOPLASMS; OPTICAL IMAGING; PHOTOCHEMOTHERAPY;

EID: 84923218517     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc5003967     Document Type: Review

References (57)

1. Ntziachristos, V. (2010) Going deeper than microscopy: the optical imaging frontier in biology Nat. Methods 7, 603-14
2. Xu, H., Li, Q., Wang, L., He, Y., Shi, J., Tang, B., and Fan, C. (2014) Nanoscale optical probes for cellular imaging Chem. Soc. Rev. 43, 2650-61
3. Loening, A. M., Wu, A. M., and Gambhir, S. S. (2007) Red-shifted Renilla reniformis luciferase variants for imaging in living subjects Nat. Methods 4, 641-3
4. Day, R. N. and Davidson, M. W. (2009) The fluorescent protein palette: tools for cellular imaging Chem. Soc. Rev. 38, 2887-921
5. Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., Li, J. J., Sundaresan, G., Wu, A. M., Gambhir, S. S., and Weiss, S. (2005) Quantum dots for live cells, in vivo imaging, and diagnostics Science 307, 538-44
6. Achilefu, S. (2010) Introduction to concepts and strategies for molecular imaging Chem. Rev. 110, 2575-8
7. Chen, G., Qiu, H., Prasad, P. N., and Chen, X. (2014) Upconversion nanoparticles: design, nanochemistry, and applications in theranostics Chem. Rev. 114, 5161-214
8. Moerner, W. E. (2007) New directions in single-molecule imaging and analysis Proc. Natl. Acad. Sci. U. S. A. 104, 12596-602
9. Wang, F. and Liu, X. (2009) Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals Chem. Soc. Rev. 38, 976-89
10. Bouzigues, C., Gacoin, T., and Alexandrou, A. (2011) Biological applications of rare-earth based nanoparticles ACS Nano 5, 8488-505
11. Wang, F., Banerjee, D., Liu, Y., Chen, X., and Liu, X. (2010) Upconversion nanoparticles in biological labeling, imaging, and therapy Analyst 135, 1839-54
12. Gnach, A. and Bednarkiewicz, A. (2012) Lanthanide-doped up-converting nanoparticles: Merits and challenges Nano Today 7, 532-563
13. Campagnola, P. J. and Loew, L. M. (2003) Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms Nat. Biotechnol. 21, 1356-60
14. Zhou, J., Liu, Z., and Li, F. (2012) Upconversion nanophosphors for small-animal imaging Chem. Soc. Rev. 41, 1323-49
15. Wang, F., Han, Y., Lim, C. S., Lu, Y., Wang, J., Xu, J., Chen, H., Zhang, C., Hong, M., and Liu, X. (2010) Simultaneous phase and size control of upconversion nanocrystals through lanthanide doping Nature 463, 1061-5
16. Heer, S., Kompe, K., Gudel, H. U., and Haase, M. (2004) Highly efficient multicolour upconversion emission in transparent colloids of lanthanide-doped NaYF4 nanocrystals Adv. Mater. 16, 2102-+
17. Haase, M. and Schafer, H. (2011) Upconverting nanoparticles Angew. Chem., Int. Ed. 50, 5808-29
18. Auzel, F. (2004) Upconversion and anti-Stokes processes with f and d ions in solids Chem. Rev. 104, 139-73
19. Mai, H. X., Zhang, Y. W., Si, R., Yan, Z. G., Sun, L. D., You, L. P., and Yan, C. H. (2006) High-quality sodium rare-earth fluoride nanocrystals: controlled synthesis and optical properties J. Am. Chem. Soc. 128, 6426-36
20. Li, Z. and Zhang, Y. (2008) An efficient and user-friendly method for the synthesis of hexagonal-phase NaYF(4):Yb, Er/Tm nanocrystals with controllable shape and upconversion fluorescence Nanotechnology 19, 345606
21. Bogdan, N., Vetrone, F., Ozin, G. A., and Capobianco, J. A. (2011) Synthesis of ligand-free colloidally stable water dispersible brightly luminescent lanthanide-doped upconverting nanoparticles Nano Lett. 11, 835-40
22. Rantanen, T., Jarvenpaa, M. L., Vuojola, J., Kuningas, K., and Soukka, T. (2008) Fluorescence-quenching-based enzyme-activity assay by using photon upconversion Angew. Chem., Int. Ed. 47, 3811-3
23. Zhou, H. P., Xu, C. H., Sun, W., and Yan, C. H. (2009) Clean and flexible modification strategy for carboxyl/aldehyde-functionalized upconversion nanoparticles and their optical applications Adv. Funct. Mater. 19, 3892-3900
24. Wu, S., Han, G., Milliron, D. J., Aloni, S., Altoe, V., Talapin, D. V., Cohen, B. E., and Schuck, P. J. (2009) Non-blinking and photostable upconverted luminescence from single lanthanide-doped nanocrystals Proc. Natl. Acad. Sci. U. S. A. 106, 10917-21
25. Yang, Y., Shao, Q., Deng, R., Wang, C., Teng, X., Cheng, K., Cheng, Z., Huang, L., Liu, Z., Liu, X., and Xing, B. (2012) In vitro and in vivo uncaging and bioluminescence imaging by using photocaged upconversion nanoparticles Angew. Chem., Int. Ed. 51, 3125-9
26. Wang, L., Yan, R., Huo, Z., Zeng, J., Bao, J., Wang, X., Peng, Q., and Li, Y. (2005) Fluorescence resonant energy transfer biosensor based on upconversion-luminescent nanoparticles Angew. Chem., Int. Ed. 44, 6054-7
27. Nam, S. H., Bae, Y. M., Park, Y. I., Kim, J. H., Kim, H. M., Choi, J. S., Lee, K. T., Hyeon, T., and Suh, Y. D. (2011) Long-term real-time tracking of lanthanide ion doped upconverting nanoparticles in living cells Angew. Chem., Int. Ed. 50, 6093-7
28. Ostrowski, A. D., Chan, E. M., Gargas, D. J., Katz, E. M., Han, G., Schuck, P. J., Milliron, D. J., and Cohen, B. E. (2012) Controlled synthesis and single-particle imaging of bright, sub-10 nm lanthanide-doped upconverting nanocrystals ACS Nano 6, 2686-92
29. Gargas, D. J., Chan, E. M., Ostrowski, A. D., Aloni, S., Altoe, M. V., Barnard, E. S., Sanii, B., Urban, J. J., Milliron, D. J., Cohen, B. E., and Schuck, P. J. (2014) Engineering bright sub-10-nm upconverting nanocrystals for single-molecule imaging Nat. Nanotechnol. 9, 300-5
30. Zhao, J., Jin, D., Schartner, E. P., Lu, Y., Liu, Y., Zvyagin, A. V., Zhang, L., Dawes, J. M., Xi, P., Piper, J. A., Goldys, E. M., and Monro, T. M. (2013) Single-nanocrystal sensitivity achieved by enhanced upconversion luminescence Nat. Nanotechnol. 8, 729-34
31. Wang, F. and Liu, X. (2014) Multicolor tuning of lanthanide-doped nanoparticles by single wavelength excitation Acc. Chem. Res. 47, 1378-85
32. Chen, G. Y., Qiu, H. L., Fan, R. W., Hao, S. W., Tan, S., Yang, C. H., and Han, G. (2012) Lanthanide-doped ultrasmall yttrium fluoride nanoparticles with enhanced multicolor upconversion photoluminescence J. Mater. Chem. 22, 20190-20196
33. Tian, G., Gu, Z., Zhou, L., Yin, W., Liu, X., Yan, L., Jin, S., Ren, W., Xing, G., Li, S., and Zhao, Y. (2012) Mn2+ dopant-controlled synthesis of NaYF4:Yb/Er upconversion nanoparticles for in vivo imaging and drug delivery Adv. Mater. 24, 1226-31
34. Chatterjee, D. K., Rufaihah, A. J., and Zhang, Y. (2008) Upconversion fluorescence imaging of cells and small animals using lanthanide doped nanocrystals Biomaterials 29, 937-43
35. Wang, M., Mi, C. C., Wang, W. X., Liu, C. H., Wu, Y. F., Xu, Z. R., Mao, C. B., and Xu, S. K. (2009) Immunolabeling and NIR-excited fluorescent imaging of HeLa cells by using NaYF(4):Yb,Er upconversion nanoparticles ACS Nano 3, 1580-6
36. 3+ doped fluoride nanophosphors Nano Lett. 8, 3834-8
37. Chen, G., Ohulchanskyy, T. Y., Kumar, R., Agren, H., and Prasad, P. N. (2010) Ultrasmall monodisperse NaYF(4):Yb(3+)/Tm(3+) nanocrystals with enhanced near-infrared to near-infrared upconversion photoluminescence ACS Nano 4, 3163-8
38. Chen, G., Shen, J., Ohulchanskyy, T. Y., Patel, N. J., Kutikov, A., Li, Z., Song, J., Pandey, R. K., Agren, H., Prasad, P. N., and Han, G. (2012) alpha-NaYbF4:Tm(3+))/CaF2 core/shell nanoparticles with efficient near-infrared to near-infrared upconversion for high-contrast deep tissue bioimaging ACS Nano 6, 8280-7
39. 4:Yb,Er nanoparticle-based dual-modal molecular probes for imaging tiny tumors in vivo ACS Nano 7, 7227-40
40. Sun, Y., Zhu, X., Peng, J., and Li, F. (2013) Core-shell lanthanide upconversion nanophosphors as four-modal probes for tumor angiogenesis imaging ACS Nano 7, 11290-300
41. Esipova, T. V., Ye, X., Collins, J. E., Sakadzic, S., Mandeville, E. T., Murray, C. B., and Vinogradov, S. A. (2012) Dendritic upconverting nanoparticles enable in vivo multiphoton microscopy with low-power continuous wave sources Proc. Natl. Acad. Sci. U. S. A. 109, 20826-31
42. Ni, D., Zhang, J., Bu, W., Xing, H., Han, F., Xiao, Q., Yao, Z., Chen, F., He, Q., Liu, J., Zhang, S., Fan, W., Zhou, L., Peng, W., and Shi, J. (2014) Dual-targeting upconversion nanoprobes across the blood-brain barrier for magnetic resonance/fluorescence imaging of intracranial glioblastoma ACS Nano 8, 1231-42
43. Shen, J., Chen, G. Y., Vu, A. M., Fan, W., Bilsel, O. S., Chang, C. C., and Han, G. (2013) Engineering the upconversion nanoparticle excitation wavelength: cascade sensitization of tri-doped upconversion colloidal nanoparticles at 800 nm Adv. Opt. Mater. 1, 644-650
44. Wang, Y. F., Liu, G. Y., Sun, L. D., Xiao, J. W., Zhou, J. C., and Yan, C. H. (2013) Nd(3+)-sensitized upconversion nanophosphors: efficient in vivo bioimaging probes with minimized heating effect ACS Nano 7, 7200-6
45. Xie, X., Gao, N., Deng, R., Sun, Q., Xu, Q. H., and Liu, X. (2013) Mechanistic investigation of photon upconversion in Nd(3+)-sensitized core-shell nanoparticles J. Am. Chem. Soc. 135, 12608-11
46. Zhang, C., Zhou, H. P., Liao, L. Y., Feng, W., Sun, W., Li, Z. X., Xu, C. H., Fang, C. J., Sun, L. D., Zhang, Y. W., and Yan, C. H. (2010) Luminescence modulation of ordered upconversion nanopatterns by a photochromic diarylethene: rewritable optical storage with nondestructive readout Adv. Mater. 22, 633-7
47. Carling, C. J., Nourmohammadian, F., Boyer, J. C., and Branda, N. R. (2010) Remote-control photorelease of caged compounds using near-infrared light and upconverting nanoparticles Angew. Chem., Int. Ed. 49, 3782-5
48. Min, Y., Li, J., Liu, F., Yeow, E. K., and Xing, B. (2014) Near-infrared light-mediated photoactivation of a platinum antitumor prodrug and simultaneous cellular apoptosis imaging by upconversion-luminescent nanoparticles Angew. Chem., Int. Ed. 53, 1012-6
49. 2 core/shell nanoparticles for in situ real-time recorded biocompatible photoactivation Small 9, 3213-7
50. Guo, Y., Kumar, M., and Zhang, P. (2007) Nanoparticle-based photosensitizers under CW infrared excitation Chem. Mater. 19, 6071-6072
51. Tian, G., Ren, W. L., Yan, L., Jian, S., Gu, Z. J., Zhou, L. J., Jin, S., Yin, W. Y., Li, S. J., and Zhao, Y. L. (2013) Red-emitting upconverting nanoparticles for photodynamic therapy in cancer cells under near-infrared excitation Small 9, 1929-1938
52. Wang, C., Tao, H., Cheng, L., and Liu, Z. (2011) Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles Biomaterials 32, 6145-54
53. Idris, N. M., Gnanasammandhan, M. K., Zhang, J., Ho, P. C., Mahendran, R., and Zhang, Y. (2012) In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers Nat. Med. 18, 1580-5
54. Sun, Y., Feng, W., Yang, P., Huang, C., and Li, F. The biosafety of lanthanide upconversion nanomaterials. Chem. Soc. Rev. [Online early access] DOI: 10.1039/c4cs00175c.
55. Gnach, A., Lipinski, T., Bednarkiewicz, A., Rybaka, J., and Capobianco, J. A. Upconverting nanoparticles: assessing the toxicity. Chem. Soc. Rev. [Online early access] DOI: 10.1039/c4cs00177j.
56. Xing, H., Zhang, S., Bu, W., Zheng, X., Wang, L., Xiao, Q., Ni, D., Zhang, J., Zhou, L., Peng, W., Zhao, K., Hua, Y., and Shi, J. (2014) Ultrasmall NaGdF4 nanodots for efficient MR angiography and atherosclerotic plaque imaging Adv. Mater. 26, 3867-3872
57. Zou, W. Q., Visser, C., Maduro, J. A., Pshenichnikov, M. S., and Hummelen, J. C. (2012) Broadband dye-sensitized upconversion of near-infrared light Nat. Photonics 6, 560-564