Focal chromosomal copy number aberrations identify CMTM8 and GPR177 as new candidate driver genes in osteosarcoma

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Both, Joeri ^a   Krijgsman, Oscar ^b   Bras, Johannes ^a   Schaap, Gerard R ^a   Baas, Frank ^a   Ylstra, Bauke ^b   Hulsebos, Theo J M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; RNA; SCATTER FACTOR RECEPTOR; WNT PROTEIN; CHEMOKINE; CMTM8 PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; GPR177 PROTEIN, HUMAN; MARVEL DOMAIN CONTAINING PROTEIN; SIGNAL PEPTIDE; TUMOR SUPPRESSOR PROTEIN;

ADOLESCENT; ADULT; ARTICLE; CANCER TISSUE; CARCINOGENESIS; CHILD; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CMTM8 GENE; CONTROLLED STUDY; FEMALE; FETUS; FOCAL CHROMOSOMAL COPY NUMBER ABERRATION; GENE DOSAGE; GENE EXPRESSION; GENE IDENTIFICATION; GPR177 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MICROARRAY ANALYSIS; ONCOGENE; OSTEOBLAST; OSTEOSARCOMA; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR SUPPRESSOR GENE; ANTAGONISTS AND INHIBITORS; BONE TUMOR; CELL TRANSFORMATION; COMPARATIVE GENOMIC HYBRIDIZATION; COPY NUMBER VARIATION; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; MIDDLE AGED; WNT SIGNALING PATHWAY; YOUNG ADULT;

ADOLESCENT; ADULT; BONE NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; CHEMOKINES; CHILD; CHROMOSOME ABERRATIONS; COMPARATIVE GENOMIC HYBRIDIZATION; DNA COPY NUMBER VARIATIONS; FEMALE; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MARVEL DOMAIN-CONTAINING PROTEINS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENES; OSTEOSARCOMA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTO-ONCOGENE PROTEINS C-MET; RECEPTORS, G-PROTEIN-COUPLED; TUMOR SUPPRESSOR PROTEINS; WNT SIGNALING PATHWAY; YOUNG ADULT;

EID: 84923196093     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115835     Document Type: Article

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