A general linear relaxometry model of R1 using imaging data

Magnetic Resonance in Medicine

Volumn 73, Issue 3, 2015, Pages 1309-1314

  Callaghan, Martina F ^a   Helms, Gunther ^b   Lutti, Antoine ^c   Mohammadi, Siawoosh ^a   Weiskopf, Nikolaus ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

3T; Longitudinal relaxation; Magnetization transfer; MT; PD; PD ; Quantitative; R1; R2 ; Relaxometry; T1; T2 ; Transverse relaxation; Water content

Indexed keywords

IRON; MAGNETIZATION; PALLADIUM; TISSUE; WATER CONTENT;

LONGITUDINAL RELAXATION; MAGNETIZATION TRANSFER; QUANTITATIVE; RELAXOMETRY; TRANSVERSE RELAXATION;

MACROMOLECULES;

IRON;

ADULT; AGED; ANATOMICAL CONCEPTS; ARTICLE; BRAIN MAPPING; FEMALE; GRAY MATTER; HUMAN; LEISURE; MACROMOLECULE; MALE; NEUROIMAGING; NORMAL HUMAN; STATISTICAL MODEL; TISSUE STRUCTURE; TISSUES; VALIDITY; WATER CONTENT; WHITE MATTER; ALGORITHM; BIOLOGICAL MODEL; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; IMAGE ENHANCEMENT; IMPEDANCE; MAGNETIC FIELD; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; REFERENCE VALUE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; THREE DIMENSIONAL IMAGING; YOUNG ADULT;

ADULT; AGED; ALGORITHMS; COMPUTER SIMULATION; ELECTRIC IMPEDANCE; FEMALE; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; LINEAR MODELS; MAGNETIC FIELDS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 84923130162     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.25210     Document Type: Article

References (30)

1. Fatouros PP, Marmarou A. Use of magnetic resonance imaging for in vivo measurements of water content in human brain: method and normal values. J Neurosurg 1999;90:109-115.
2. Fatouros PP, Marmarou A, Kraft KA, Inao S, Schwarz FP. In vivo brain water determination by T1 measurements: effect of total water content, hydration fraction, and field strength. Magn Reson Med 1991;17:402-413.
3. Kaneoke Y, Furuse M, Inao S, Saso K, Yoshida K, Motegi Y, Mizuno M, Izawa A. Spin-lattice relaxation times of bound water-its determination and implications for tissue discrimination. Magn Reson Imaging 1987;5:415-420.
4. Shuter B, Wang SC, Roche J, Briggs G, Pope JM. Relaxivity of Gd-EOB-DTPA in the normal and biliary obstructed guinea pig. J Magn Reson Imaging 1998;8:853-861.
5. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med 1994;32:66-76.
6. Kamman RL, Go KG, Brouwer W, Berendsen HJ. Nuclear magnetic resonance relaxation in experimental brain edema: effects of water concentration, protein concentration, and temperature. Magn Reson Med 1988;6:265-274.
7. Fullerton GD, Potter JL, Dornbluth NC. NMR relaxation of protons in tissues and other macromolecular water solutions. Magn Reson Imaging 1982;1:209-226.
8. Gelman N, Ewing JR, Gorell JM, Spickler EM, Solomon EG. Interregional variation of longitudinal relaxation rates in human brain at 3.0 T: relation to estimated iron and water contents. Magn Reson Med 2001;45:71-79.
9. Wolff SD, Balaban RS. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn Reson Med 1989;10: 135-144.
10. Helms G, Dathe H, Kallenberg K, Dechent P. High-resolution maps of magnetization transfer with inherent correction for RF inhomogeneity and T1 relaxation obtained from 3D FLASH MRI. Magn Reson Med 2008;60:1396-1407.
11. Helms G, Piringer A. Simultaneous measurement of saturation and relaxation in human brain by repetitive magnetization transfer pulses. NMR Biomed 2005;18:44-50.
12. Schmierer K, Scaravilli F, Altmann DR, Barker GJ, Miller DH. Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann Neurol 2004;56:407-415.
13. Langkammer C, Krebs N, Goessler W, Scheurer E, Ebner F, Yen K, Fazekas F, Ropele S. Quantitative MR imaging of brain iron: a postmortem validation study. Radiology 2010;257:455-462.
14. Weiskopf N, Suckling J, Williams G, Correia MM, Inkster B, Tait R, Ooi C, Bullmore ET, Lutti A. Quantitative multi-parameter mapping of R1, PD∗, MT, and R2∗ at 3T: a multi-center validation. Front Neurosci 2013;7:1-11.
15. Helms G, Dechent P. Increased SNR and reduced distortions by averaging multiple gradient echo signals in 3D FLASH imaging of the human brain at 3T. J Magn Reson Imaging 2009;29: 198-204.
16. Helms G, Dathe H, Dechent P. Quantitative FLASH MRI at 3T using a rational approximation of the Ernst equation. Magn Reson Med 2008; 59:667-672.
17. Lutti A, Stadler J, Josephs O, Windischberger C, Speck O, Bernarding J, Hutton C, Weiskopf N. Robust and fast whole brain mapping of the RF transmit field B1 at 7T. PLoS One 2012;7:e32379.
18. Preibisch C, Deichmann R. Influence of RF spoiling on the stability and accuracy of T1 mapping based on spoiled FLASH with varying flip angles. Magn Reson Med 2009;61:125-135.
19. Sereno MI, Lutti A, Weiskopf N, Dick F. Mapping the Human Cortical Surface by Combining Quantitative T1 with Retinotopy. Cereb Cortex 2013;23:2261-2268.
20. Dick F, Tierney AT, Lutti A, Josephs O, Sereno MI, Weiskopf N. In vivo functional and myeloarchitectonic mapping of human primary auditory areas. J Neurosci 2012;32:16095-16105.
21. Lutti A, Dick F, Sereno MI, Weiskopf N. Using high-resolution quantitative mapping of R1 as an index of cortical myelination. Neuroimage 2013:1-13.
22. Helms G, Dathe H, Dechent P. Modeling the influence of TR and excitation flip angle on the magnetization transfer ratio (MTR) in human brain obtained from 3D spoiled gradient echo MRI. Magn Reson Med 2010;64:177-185.
23. Rooney WD, Johnson G, Li X, Cohen ER, Kim S-G, Ugurbil K, Springer CS. Magnetic field and tissue dependencies of human brain longitudinal 1H2O relaxation in vivo. Magn Reson Med 2007; 57:308-318.
24. Ashburner J, Friston KJ. Unified segmentation. Neuroimage 2005;26: 839-851.
25. Helms G, Hagberg GE. Pulsed saturation of the standard two-pool model for magnetization transfer. Part I: the steady state. Concepts Magn Reson 2004;21A:37-49.
26. Li X, Rooney WD, Springer CS. A unified magnetic resonance imaging pharmacokinetic theory: intravascular and extracellular contrast reagents. Magn Reson Med 2005;54:1351-1359.
27. Connor JR, Menzies SL. Relationship of iron to oligodendrocytes and myelination. Glia 1996;17:83-93.
28. Bender B, Klose U. The in vivo influence of white matter fiber orientation towards B(0) on T2∗ in the human brain. NMR Biomed 2010; 23:1071-1076.
29. Wharton S, Bowtell R. Fiber orientation-dependent white matter contrast in gradient echo MRI. Proc Natl Acad Sci U S A 2012;109: 18559-18564.
30. Wharton S, Bowtell R. Gradient echo based fiber orientation mapping using r2∗ and frequency difference measurements. Neuroimage 2013; 83:1011-1023.