Relaxivity of Gd-EOB-DTPA in the normal and biliary obstructed guinea pig

Journal of Magnetic Resonance Imaging

Volumn 8, Issue 4, 1998, Pages 853-861

  Shuter, B ^a   Wang, S C ^a   Roche, J ^a   Briggs, G ^a   Pope, J M ^b  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Gd EOB DTPA; Guinea pig; In vivo; Kidney; Liver; Relaxivity; T1; T2

Indexed keywords

CONTRAST MEDIUM; GADOXETIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE DUCT OBSTRUCTION; CONTROLLED STUDY; DIAGNOSTIC VALUE; DOSE CALCULATION; GUINEA PIG; KIDNEY CORTEX; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TISSUE DISTRIBUTION; VISCOSITY; WATER CONTENT;

ANIMALS; BILE DUCTS; CHOLESTASIS; CONTRAST MEDIA; GADOLINIUM DTPA; GUINEA PIGS; KIDNEY; LIVER; MAGNETIC RESONANCE IMAGING; MALE;

EID: 0031848230     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmri.1880080415     Document Type: Article

References (21)

1. Schuhmann-Giampieri G, Schmitt-Willich H, Press W-R, Negishi C, Weinmann H-J, Speck U. Preclinlcal evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system. Radiology 1992; 183:59-64.
2. Marchal G, Zhang X, Ni Y, Van Hecke P, Yu J, Baert AL. Comparison between Gd-DTPA, Gd-EOB-DTPA and Mn-DPDP in induced HCC in rats. Magn Reson Imaging 1993; 11: 665-674.
3. Weinmann H-J, Brash RC, Press WR, Wesbey GE. Characteristics of gadolinium-DTPA complex: a potential NMR contrast agent. Am J Roentgenol 1984; 142:619-624.
4. Lauffer RB. Paramagnetic complexes as water proton relaxation agents for NMR imaging: theory and design. Chem Rev 1987; 87:901-927.
5. Nelson TR, Hendrick RE, Hendee WR. Selection of pulse sequences producing maximum tissue contrast in magnetic resonance imaging. Magn Reson Imaging 1984; 2:285-294.
6. Davis PL, Parker DL, Nelson JA, Gillen JS, Runge VM. Interactions of paramagnetic contrast agents and the spin echo pulse sequence. Invest Radiol 1988; 23:381-388.
7. Unger EC, Ugurbil K, Latchaw RE. Contrast agents for cerebral perfusion MR imaging. J Magn Reson Imaging 1994; 4:235-242.
8. Weinmann H-J, Schuhmann-Giampieri G, Schmitt-Willich H, Vogler H, Frenzel T, Gries H. A new lipophilic gadolinium chelate as a tissue-specific contrast medium for MRI. Magn Reson Med 1991; 22:233-237.
9. Shuter B, Tofts PS, Wang S-C, Pope JM. The relaxivity of Gd-EOB-DTPA and Gd-DTPA in liver and kidney of the Wistar rat. Magn Reson Imaging 1996; 14:243-253.
10. Shuter B, Tofts PS, Pope JM. The effect of sacrifice on image signal, T1, T2 and T2* in liver, kidney and brain of the Wistar rat. Magn Reson Imaging 1995; 13:563-574.
11. Tofts PS, Johnson G. A SAFE (Saturate AFter the Echo) sequence to eliminate an artefact in the measurement of T2 in partially saturated NMR systems. Phys Med Biol 1987; 32: 1345-1353.
12. Ross DA, Harris CC. Measurement of radioactivity. In: Wagner HJ, ed. Principles of nuclear medicine. Philadelphia, PA: WB Saunders Company, 1968; 136.
13. Landaw EM, DiStefano JJ III. Multiexponential, multicompartmental and noncompartmental modeling, II: data analysis and statistical considerations. Am J Physiol 1984; 246:R665-R677.
14. Schwickert HC, Roberts TPL, Shames DM, et al. Quantification of liver blood volume: comparison of ultra short TI inversion recovery echo planar imaging (ULSTIR-EPI) with dynamic 3D-gradient recalled echo imaging. Magn Reson Med 1995; 34:845-852.
15. Graham SJ, Stanchev PL, Bronskill MJ. Criteria for analysis of multicomponent tissue T2 relaxation data. Magn Reson Med 1996; 35:370-378.
16. Foster MA, Hutchison JMS. Practical NMR imaging. Oxford, UK: IRL Press, 1987; 40.
17. Tofts PS, Shuter B, Pope JM. Ni-DTPA doped agarose gel: a phantom material for Gd-DTPA enhancement measurements. Magn Reson Imaging 1992; 11:125-133.
18. 2- to everything else. Magn Reson Med 1991; 22:183-190.
19. Clement O, Muhler A, Vexler V, Berthezene Y, Brasch RC. Gd-EOB-DTPA, a new liver-specific MR contrast agent: relaxivity, kinetics and enhancement patterns in normal rats. In: Book of abstracts: Society of Magnetic Resonance in Medicine 1991. Berkeley, CA: Society of Magnetic Resonance in Medicine, 1991; 1047.
20. Fabry ME, San George RC. Effect of magnetic susceptibility on NMR signals arising from red cells: a warning. Biochemistry 1983; 22:4119-4125.
21. Lauffer RB, Brady TJ. Preparation and water relaxation properties of proteins labeled with paramagnetic metal chelates. Magn Reson Imaging 1985; 3:11-16.