The traditional Chinese medicinal formula BDL301 suppresses tumor growth by inhibiting STAT3 pathway and inducing apoptosis in colorectal cancer cells

DNA and Cell Biology

Volumn 34, Issue 3, 2015, Pages 178-188

  Chu, Li ^a,b,c   Zhao, Huaxin ^a   Fang, Juemin ^a   Li, Chunyan ^a   Liu, Zhuqing ^a   Cui, Ran ^a   Hu, Fei ^a   Zhang, Xi ^a   Chen, Yijing ^a   Han, Hui ^a   Cao, Chuanhai ^d   Xu, Qing ^a  

^a TONGJI UNIVERSITY   (China)

^b FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^c FUDAN UNIVERSITY   (China)

^d UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BDL 301; BETA ACTIN; CD31 ANTIGEN; CHINESE DRUG; I KAPPA B ALPHA; INTERLEUKIN 6; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; STAT3 PROTEIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; BDL301; HERBACEOUS AGENT;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL VIABILITY; CHINESE MEDICINE; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; FEMALE; G2 PHASE CELL CYCLE CHECKPOINT; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR REGRESSION; TUMOR VOLUME; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE; CHEMISTRY; COLORECTAL NEOPLASMS; DOSE RESPONSE; DRUG EFFECTS; HCT116 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE; VASCULARIZATION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD31; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; HCT116 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEDICINE, CHINESE TRADITIONAL; MICE, INBRED BALB C; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TUMOR BURDEN;

EID: 84923116016     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2014.2532     Document Type: Article

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