메뉴 건너뛰기




Volumn 25, Issue 2, 2015, Pages 73-81

"Beauty is a light in the heart": The transformative potential of optogenetics for clinical applications in cardiovascular medicine

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR DISEASE; CONCEPTUAL FRAMEWORK; FEASIBILITY STUDY; HUMAN; ILLUMINATION; IN VITRO STUDY; MATHEMATICAL COMPUTING; MONOLAYER CULTURE; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SIMULATION; TECHNOLOGY; TRANSGENIC ANIMAL; CARDIOVASCULAR DISEASES; COMPUTER SIMULATION; PROCEDURES;

EID: 84923104375     PISSN: 10501738     EISSN: 18732615     Source Type: Journal    
DOI: 10.1016/j.tcm.2014.10.004     Document Type: Review
Times cited : (29)

References (46)
  • 2
    • 26444621497 scopus 로고    scopus 로고
    • Millisecond-timescale, genetically targeted optical control of neural activity
    • Boyden E.S., Zhang F., Bamberg E., Nagel G., Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci 2005, 8:1263-1268.
    • (2005) Nat Neurosci , vol.8 , pp. 1263-1268
    • Boyden, E.S.1    Zhang, F.2    Bamberg, E.3    Nagel, G.4    Deisseroth, K.5
  • 3
    • 33749020262 scopus 로고    scopus 로고
    • Channelrhodopsin-2 and optical control of excitable cells
    • Zhang F., Wang L.P., Boyden E.S., Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nat Methods 2006, 3:785-792.
    • (2006) Nat Methods , vol.3 , pp. 785-792
    • Zhang, F.1    Wang, L.P.2    Boyden, E.S.3    Deisseroth, K.4
  • 5
    • 84876012218 scopus 로고    scopus 로고
    • Optogenetics and translational medicine
    • 177ps5
    • Chow B.Y., Boyden E.S. Optogenetics and translational medicine. Sci Transl Med 2013, 5:177ps5.
    • (2013) Sci Transl Med , vol.5
    • Chow, B.Y.1    Boyden, E.S.2
  • 7
    • 84893151493 scopus 로고    scopus 로고
    • See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?
    • Boyle P.M., Entcheva E., Trayanova N.A. See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?. Expert Rev Cardiovasc Ther 2014, 12:17-20.
    • (2014) Expert Rev Cardiovasc Ther , vol.12 , pp. 17-20
    • Boyle, P.M.1    Entcheva, E.2    Trayanova, N.A.3
  • 8
    • 0042237732 scopus 로고    scopus 로고
    • Defibrillation efficacy and pain perception of two biphasic waveforms for internal cardioversion of atrial fibrillation
    • Jung J., Hahn S.J., Heisel A., Buob A., Schubert B.D., Siaplaouras S. Defibrillation efficacy and pain perception of two biphasic waveforms for internal cardioversion of atrial fibrillation. J Cardiovasc Electrophysiol 2003, 14:837-840.
    • (2003) J Cardiovasc Electrophysiol , vol.14 , pp. 837-840
    • Jung, J.1    Hahn, S.J.2    Heisel, A.3    Buob, A.4    Schubert, B.D.5    Siaplaouras, S.6
  • 9
    • 12344323809 scopus 로고    scopus 로고
    • Electrical stimulation of excitable tissue: design of efficacious and safe protocols
    • Merrill D.R., Bikson M., Jefferys J.G.R. Electrical stimulation of excitable tissue: design of efficacious and safe protocols. J Neurosci Methods 2005, 141:171-198.
    • (2005) J Neurosci Methods , vol.141 , pp. 171-198
    • Merrill, D.R.1    Bikson, M.2    Jefferys, J.G.R.3
  • 13
    • 80053129860 scopus 로고    scopus 로고
    • Multiscale computational models for optogenetic control of cardiac function
    • Abilez O.J., Wong J., Prakash R., Deisseroth K., Zarins C.K., Kuhl E. Multiscale computational models for optogenetic control of cardiac function. Biophys J 2011, 101:1326-1334.
    • (2011) Biophys J , vol.101 , pp. 1326-1334
    • Abilez, O.J.1    Wong, J.2    Prakash, R.3    Deisseroth, K.4    Zarins, C.K.5    Kuhl, E.6
  • 15
    • 84897013419 scopus 로고    scopus 로고
    • Modulation of cardiac tissue electrophysiological properties with light-sensitive proteins
    • Nussinovitch U., Shinnawi R., Gepstein L. Modulation of cardiac tissue electrophysiological properties with light-sensitive proteins. Cardiovasc Res 2014, 102:176-187.
    • (2014) Cardiovasc Res , vol.102 , pp. 176-187
    • Nussinovitch, U.1    Shinnawi, R.2    Gepstein, L.3
  • 16
    • 84901403361 scopus 로고    scopus 로고
    • Optogenetic activation of Gq signalling modulates pacemaker activity of cardiomyocytes
    • Beiert T., Bruegmann T., Sasse P. Optogenetic activation of Gq signalling modulates pacemaker activity of cardiomyocytes. Cardiovasc Res 2014, 102:507-516.
    • (2014) Cardiovasc Res , vol.102 , pp. 507-516
    • Beiert, T.1    Bruegmann, T.2    Sasse, P.3
  • 17
    • 84884906500 scopus 로고    scopus 로고
    • ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation
    • Lin J.Y., Knutsen P.M., Muller A., Kleinfeld D., Tsien R.Y. ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation. Nat Neurosci 2013, 16:1499-1508.
    • (2013) Nat Neurosci , vol.16 , pp. 1499-1508
    • Lin, J.Y.1    Knutsen, P.M.2    Muller, A.3    Kleinfeld, D.4    Tsien, R.Y.5
  • 19
    • 84894049643 scopus 로고    scopus 로고
    • Advances in modeling ventricular arrhythmias: from mechanisms to the clinic
    • Trayanova N.A., Boyle P.M. Advances in modeling ventricular arrhythmias: from mechanisms to the clinic. Wiley Interdiscip Rev Syst Biol Med 2014, 6:209-224.
    • (2014) Wiley Interdiscip Rev Syst Biol Med , vol.6 , pp. 209-224
    • Trayanova, N.A.1    Boyle, P.M.2
  • 20
    • 37349092335 scopus 로고    scopus 로고
    • Spectral characteristics of the photocycle of channelrhodopsin-2 and its implication for channel function
    • Bamann C., Kirsch T., Nagel G., Bamberg E. Spectral characteristics of the photocycle of channelrhodopsin-2 and its implication for channel function. J Mol Biol 2008, 375:686-694.
    • (2008) J Mol Biol , vol.375 , pp. 686-694
    • Bamann, C.1    Kirsch, T.2    Nagel, G.3    Bamberg, E.4
  • 22
    • 84884679394 scopus 로고    scopus 로고
    • Computational optogenetics: empirically-derived voltage- and light-sensitive channelrhodopsin-2 model
    • e1003220-e
    • Williams J.C., Xu J., Lu Z., Klimas A., Chen X., Ambrosi C.M., et al. Computational optogenetics: empirically-derived voltage- and light-sensitive channelrhodopsin-2 model. PLoS Comput Biol 2013, 9:e1003220-e.
    • (2013) PLoS Comput Biol , vol.9
    • Williams, J.C.1    Xu, J.2    Lu, Z.3    Klimas, A.4    Chen, X.5    Ambrosi, C.M.6
  • 23
    • 84923103082 scopus 로고    scopus 로고
    • Channelrhodopsin2 current during the action potential: "optical AP clamp" and approximation
    • Entcheva E., Williams J.C. Channelrhodopsin2 current during the action potential: "optical AP clamp" and approximation. Sci Rep 2014, 4:5838.
    • (2014) Sci Rep , vol.4 , pp. 5838
    • Entcheva, E.1    Williams, J.C.2
  • 24
    • 79959731191 scopus 로고    scopus 로고
    • A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction
    • Prasad K-MR, Smith R.S., Xu Y., French B.A. A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction. J Gene Med 2011, 13:333-341.
    • (2011) J Gene Med , vol.13 , pp. 333-341
    • Prasad, K.-M.R.1    Smith, R.S.2    Xu, Y.3    French, B.A.4
  • 25
    • 78650979325 scopus 로고    scopus 로고
    • Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution
    • Prasad K.M., Xu Y., Yang Z., Acton S.T., French B.A. Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution. Gene Ther 2011, 18:43-52.
    • (2011) Gene Ther , vol.18 , pp. 43-52
    • Prasad, K.M.1    Xu, Y.2    Yang, Z.3    Acton, S.T.4    French, B.A.5
  • 26
    • 34547866713 scopus 로고    scopus 로고
    • Finding fluorescent needles in the cardiac haystack: tracking human mesenchymal stem cells labeled with quantum dots for quantitative in vivo three-dimensional fluorescence analysis
    • Rosen A.B., Kelly D.J., Schuldt A.J.T., Lu J., Potapova I.A., Doronin S.V., et al. Finding fluorescent needles in the cardiac haystack: tracking human mesenchymal stem cells labeled with quantum dots for quantitative in vivo three-dimensional fluorescence analysis. Stem Cells 2007, 25:2128-2138.
    • (2007) Stem Cells , vol.25 , pp. 2128-2138
    • Rosen, A.B.1    Kelly, D.J.2    Schuldt, A.J.T.3    Lu, J.4    Potapova, I.A.5    Doronin, S.V.6
  • 27
    • 33646200057 scopus 로고    scopus 로고
    • Synthesis of voltage-sensitive optical signals: application to panoramic optical mapping
    • Bishop M.J., Rodriguez B., Eason J., Whiteley J.P., Trayanova N., Gavaghan D.J. Synthesis of voltage-sensitive optical signals: application to panoramic optical mapping. Biophys J 2006, 90:2938-2945.
    • (2006) Biophys J , vol.90 , pp. 2938-2945
    • Bishop, M.J.1    Rodriguez, B.2    Eason, J.3    Whiteley, J.P.4    Trayanova, N.5    Gavaghan, D.J.6
  • 28
    • 0035138954 scopus 로고    scopus 로고
    • Visualizing excitation waves inside cardiac muscle using transillumination
    • Baxter W.T., Mironov S.F., Zaitsev A.V., Jalife J., Pertsov A.M. Visualizing excitation waves inside cardiac muscle using transillumination. Biophys J 2001, 80:516-530.
    • (2001) Biophys J , vol.80 , pp. 516-530
    • Baxter, W.T.1    Mironov, S.F.2    Zaitsev, A.V.3    Jalife, J.4    Pertsov, A.M.5
  • 29
    • 84906499657 scopus 로고    scopus 로고
    • Simulating photon scattering effects in structurally detailed ventricular models using a Monte Carlo approach
    • Bishop M.J., Plank G. Simulating photon scattering effects in structurally detailed ventricular models using a Monte Carlo approach. Front Physiol 2014, 5.
    • (2014) Front Physiol , pp. 5
    • Bishop, M.J.1    Plank, G.2
  • 32
    • 12844285608 scopus 로고    scopus 로고
    • Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer
    • Kikuchi K., McDonald A.D., Sasano T., Donahue J.K. Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer. Circulation 2005, 111:264-270.
    • (2005) Circulation , vol.111 , pp. 264-270
    • Kikuchi, K.1    McDonald, A.D.2    Sasano, T.3    Donahue, J.K.4
  • 33
    • 84892394170 scopus 로고    scopus 로고
    • Intracoronary cardiosphere-derived cells after myocardial infarction: evidence of therapeutic regeneration in the final 1-year results of the CADUCEUS trial (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction)
    • Malliaras K., Makkar R.R., Smith R.R., Cheng K., Wu E., Bonow R.O., et al. Intracoronary cardiosphere-derived cells after myocardial infarction: evidence of therapeutic regeneration in the final 1-year results of the CADUCEUS trial (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction). J Am Coll Cardiol 2014, 63:110-122.
    • (2014) J Am Coll Cardiol , vol.63 , pp. 110-122
    • Malliaras, K.1    Makkar, R.R.2    Smith, R.R.3    Cheng, K.4    Wu, E.5    Bonow, R.O.6
  • 34
    • 84870887067 scopus 로고    scopus 로고
    • Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial
    • Hare J.M., Fishman J.E., Gerstenblith G., DiFede Velazquez D.L., Zambrano J.P., Suncion V.Y., et al. Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trial. J Am Med Assoc 2012, 308:2369-2379.
    • (2012) J Am Med Assoc , vol.308 , pp. 2369-2379
    • Hare, J.M.1    Fishman, J.E.2    Gerstenblith, G.3    DiFede Velazquez, D.L.4    Zambrano, J.P.5    Suncion, V.Y.6
  • 35
    • 80155194177 scopus 로고    scopus 로고
    • Stem cell engraftment and survival in the ischemic heart
    • Wu K.H., Mo X.M., Han Z.C., Zhou B. Stem cell engraftment and survival in the ischemic heart. Ann Thorac Surg 2011, 92:1917-1925.
    • (2011) Ann Thorac Surg , vol.92 , pp. 1917-1925
    • Wu, K.H.1    Mo, X.M.2    Han, Z.C.3    Zhou, B.4
  • 36
    • 84902312015 scopus 로고    scopus 로고
    • Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
    • Chong J.J., Yang X., Don C.W., Minami E., Liu Y.W., Weyers J.J., et al. Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature 2014, 510:273-277.
    • (2014) Nature , vol.510 , pp. 273-277
    • Chong, J.J.1    Yang, X.2    Don, C.W.3    Minami, E.4    Liu, Y.W.5    Weyers, J.J.6
  • 37
    • 84875039623 scopus 로고    scopus 로고
    • Long-term channelrhodopsin-2 (ChR2) expression can induce abnormal axonal morphology and targeting in cerebral cortex
    • Miyashita T., Shao Y.R., Chung J., Pourzia O., Feldman D.E. Long-term channelrhodopsin-2 (ChR2) expression can induce abnormal axonal morphology and targeting in cerebral cortex. Front Neural Circuits 2013, 7:8.
    • (2013) Front Neural Circuits , vol.7 , pp. 8
    • Miyashita, T.1    Shao, Y.R.2    Chung, J.3    Pourzia, O.4    Feldman, D.E.5
  • 38
    • 84876310253 scopus 로고    scopus 로고
    • Injectable, cellular-scale optoelectronics with applications for wireless optogenetics
    • Kim T.I., McCall J.G., Jung Y.H., Huang X., Siuda E.R., Li Y., et al. Injectable, cellular-scale optoelectronics with applications for wireless optogenetics. Science 2013, 340:211-216.
    • (2013) Science , vol.340 , pp. 211-216
    • Kim, T.I.1    McCall, J.G.2    Jung, Y.H.3    Huang, X.4    Siuda, E.R.5    Li, Y.6
  • 39
    • 77958500761 scopus 로고    scopus 로고
    • Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics
    • Kim R.H., Kim D.H., Xiao J., Kim B.H., Park S.I., Panilaitis B., et al. Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics. Nat Mater 2010, 9:929-937.
    • (2010) Nat Mater , vol.9 , pp. 929-937
    • Kim, R.H.1    Kim, D.H.2    Xiao, J.3    Kim, B.H.4    Park, S.I.5    Panilaitis, B.6
  • 40
    • 84896690454 scopus 로고    scopus 로고
    • 3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium
    • Xu L., Gutbrod S.R., Bonifas A.P., Su Y., Sulkin M.S., Lu N., et al. 3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium. Nat Commun 2014, 5:3329.
    • (2014) Nat Commun , vol.5 , pp. 3329
    • Xu, L.1    Gutbrod, S.R.2    Bonifas, A.P.3    Su, Y.4    Sulkin, M.S.5    Lu, N.6
  • 42
    • 79961136138 scopus 로고    scopus 로고
    • Optogenetic manipulation of cerebellar Purkinje cell activity in vivo
    • e22400-e
    • Tsubota T., Ohashi Y., Tamura K., Sato A., Miyashita Y. Optogenetic manipulation of cerebellar Purkinje cell activity in vivo. PLoS One 2011, 6:e22400-e.
    • (2011) PLoS One , vol.6
    • Tsubota, T.1    Ohashi, Y.2    Tamura, K.3    Sato, A.4    Miyashita, Y.5
  • 44
    • 84965188339 scopus 로고    scopus 로고
    • Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach
    • Karathanos T.V., Boyle P.M., Trayanova N.A. Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach. Europace 2014, 16(Suppl 4):iv62-iv68.
    • (2014) Europace , vol.16 , pp. iv62-iv68
    • Karathanos, T.V.1    Boyle, P.M.2    Trayanova, N.A.3
  • 45
    • 84906544857 scopus 로고    scopus 로고
    • Optical mapping of optogenetically shaped cardiac action potentials
    • Park S.A., Lee S.R., Tung L., Yue D.T. Optical mapping of optogenetically shaped cardiac action potentials. Sci Rep 2014, 4:6125.
    • (2014) Sci Rep , vol.4 , pp. 6125
    • Park, S.A.1    Lee, S.R.2    Tung, L.3    Yue, D.T.4
  • 46
    • 84913600482 scopus 로고    scopus 로고
    • Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes
    • Bingen B.O., Engels M.C., Schalij M.J., Jangsangthong W., Neshati Z., Feola I., et al. Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes. Cardiovasc Res 2014, 104:194-205.
    • (2014) Cardiovasc Res , vol.104 , pp. 194-205
    • Bingen, B.O.1    Engels, M.C.2    Schalij, M.J.3    Jangsangthong, W.4    Neshati, Z.5    Feola, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.