Analysis of drugs of abuse in human plasma by dispersive liquid-liquid microextraction and high-performance liquid chromatography

Journal of Applied Toxicology

Volumn 35, Issue 4, 2015, Pages 418-425

  Fernandez P ^a   Regenjo, M ^a   Bermejo, A M ^a   Fernandez A M ^b   Lorenzo, R A ^c   Carro, A M ^c  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Drug Addiction Assistance Unit   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

DLLME; Drugs of abuse; Experimental design; HPLC PDA; Plasma

Indexed keywords

ACETONITRILE; BENZOYLECGONINE; CHLOROFORM; COCAINE; DIAMORPHINE; DISPERSANT; METHADONE; MORPHINE; MORPHINE 6 ACETATE; SOLVENT; 6-O-MONOACETYLMORPHINE; MORPHINE DERIVATIVE; STREET DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; ASSAY; CALIBRATION; DRUG ABUSE; EXPERIMENTAL DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIMIT OF DETECTION; LIQUID PHASE MICROEXTRACTION; PARTICLE SIZE; PH; PLASMA; PRIORITY JOURNAL; ULTRASOUND; VALIDATION PROCESS; ANALOGS AND DERIVATIVES; ANALYSIS; BLOOD; CHEMISTRY; COMPARATIVE STUDY; OPIATE SUBSTITUTION TREATMENT; PHOTOMETRY; PROCEDURES; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLUBILITY; SUBSTANCE ABUSE; SUBSTANCE-RELATED DISORDERS; ULTRAVIOLET SPECTROPHOTOMETRY;

ANALYTIC SAMPLE PREPARATION METHODS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; COCAINE; HUMANS; HYDROGEN-ION CONCENTRATION; LIMIT OF DETECTION; LIQUID PHASE MICROEXTRACTION; METHADONE; MORPHINE; MORPHINE DERIVATIVES; OPIATE SUBSTITUTION TREATMENT; PHOTOMETRY; REPRODUCIBILITY OF RESULTS; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; STREET DRUGS; SUBSTANCE ABUSE DETECTION; SUBSTANCE-RELATED DISORDERS; ULTRASONICS;

EID: 84923079407     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3035     Document Type: Article

References (49)

1. Bassan DM, Erdmann F, Krüll R. 2011. Quantitative determination of 43 common drugs and drugs of abuse in human serum by HPLC-MS/MS. Anal. Bioanal. Chem. 400:43-50
2. Baselt RC. 2011. Disposition of Toxic Drugs and Chemicals in Man. Biomedical Publications: Seal Beach.
3. Bjørk MK, Simonsen KW, Andersen DW, Dalsgaard PW, Siguroardóttir SR, Linnet K, Rasmussen BS. 2013. Quantification of 31 illicit and medicinal drugs and metabolites in whole blood by fully automated solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 405:2607-2617.
4. Bjørk MK, Nielsen MKK, Markussen LØ, Klinke HB, Linnet K. 2010. Determination of 19 drugs of abuse and metabolites in whole blood by high-performance liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 396:2393-2401.
5. Cheng J, Matsadiq G, Liu L, Zhou YW, Chen G. 2011. Development of a model ultrasound-assisted surfactant-enhaced emulsification microextraction method and its application to the analysis of eleven polycyclic aromatic hydrocarbons at trace levels in water. J. Chromatogr. A 1218:2476-2482.
6. Concheiro M, De Castro A, Quintela O, López-Rivadulla M, Cruz A. 2006. Determination of drugs of abuse and their metabolites in human plasma by liquid chromatography-mass spectrometry. An application to 156 road fatalities. J. Chromatogr. B 832:81-89.
7. Dowling G, Regan L. 2011. A new mixed mode solid phase extraction strategy for opioids, cocaine, amphetamines and adulterants in human blood with hybrid liquid chromatography tandem mass spectrometry detection. J. Pharm. Biomed. Anal. 54:1136-1145.
8. Ebrahimzadeh H, Khezri E, Kamarei F. 2010. Determination of methadone in biological samples using liquid phase microextraction with back extraction combined with LC. Chromatographia 72:231-238.
9. EMCDDA (European Monitoring Centre for Drugs and Drug Addiction). 2012. Annual report 2012: The State of the Drugs Problem in Europe. Publications Office of the European Union: Luxembourg.
10. Fernández P, González C, Pena MT, Carro AM, Lorenzo RA. 2013. A rapid ultrasound-assisted dispersive liquid-liquid microextraction followed by ultra-performance liquid chromatography for the simultaneous determination of seven benzodiazepines in human plasma samples. Anal. Chim. Acta 767:88-96.
11. Fernández P, Lago M, Lorenzo RA, Carro AM, Bermejo AM, Tabernero MJ. 2007. Microwave-assisted extraction and HPLC-DAD determination of drugs of abuse in human plasma. J. Anal. Toxicol. 31:388-393.
12. Fernández P, Morales L, Vázquez C, Bermejo AM, Tabernero MJ. 2006. HPLC-DAD determination of opioids, cocaine and their metabolites in plasma. Forensic Sci. Int. 161: 31-35.
13. Fineschi V, Centini F, Monciotti F, Turillazzi E. 2002. The cocaine "body stuffer" syndrome: a fatal case. Forensic Sci. Int. 126:7-10.
14. Food and Drug Administration (FDA), U.S. Department of Health and Human Services, Guidance for Industry, Bioanalytical Method Validation (2001). http://www.fda.gov/cder/guidance/4252fnl.pdf.
15. Giroud C, Michaud K, Sporkert F, Eap C, Augsburger M, Cardinal P. 2004. A fatal overdose of cocaine associated with coingestion of marijuana, buprenorphine and fluoxetine. Body fluids and tissue distribution of cocaine and its metabolites determined by hydrophilic interaction chromatography-mass spectrometry. J. Anal. Toxicol. 28:464-474.
16. He Y, Lee HK. 1997. Liquid-phase microextraction in a single drop of organic solvent by using a conventional microsyringe. Anal. Chem. 69:4634-4640.
17. International Conference on Harmonization. 2005. Validation of analytical procedures: Methodology ICH Q2 B. http://www.ich.org/LOB/media/MEDIA417.pdf
18. Jeannot MA, Cantwell FF. 1996. Solvent microextraction into a single drop. Anal. Chem. 68:2236-2240.
19. Jia C, Zhu X, Chen L, He M, Yu P, Zhao E. 2010. Extraction of organophosphorus pesticides in water and juice using ultrasound-assisted emulsification-microextraction. J. Sep. Sci. 33:244-250.
20. Kohler I, Schappler J, Sierro T, Rudaz S. 2013. Dispersive liquid-liquid microextraction combined with capillary electrophoresis and time-of-flight mass spectrometry for urine analysis. J. Pharm. Biomed. Anal. 73:82289.
21. Lee J, Lee HK, Rasmussen KE, Pedersen-Bjergaard S. 2008. Environmental and bioanalytical applications of hollow fiber membrane liquid-phase microextraction: a review. Anal. Chim. Acta 624:253-268.
22. Leong M, Huang SD. 2008. Dispersive liquid-liquid microextraction method based on solidification of floating organic drop combined with gas chromatography with electron-capture or mass spectrometry detection. J. Chromatogr. A 1211:8-12.
23. Lewis GA, Mathieu D, Phan-Tan-Luu R. 1999. Pharmaceutical experimental design. Marcel Dekker: New York.
24. Li Y, Hu J, Liu X, Fu L, Zhang X, Wang X. 2008. Dispersive liquid-liquid microextraction followed by reversed phase HPLC for the determination of decabrominated diphenyl ether in natural water. J. Sep. Sci. 31:2371-2376.
25. Lili L, Xu H, Song D, Cui Y, Hu S, Zhang G. 2010. Analysis of volatile aldehide biomarkers in human blood by derivatization and dispersive liquid-liquid microextraction based on solidification of floating organic droplet method by high performance liquid chromatography. J. Chromatogr. A 1217:2365-2370.
26. Ma JJ, Du X, Zhang JW, Wang LZ. 2009. Ultrasound-assisted emulsification-microextraction combined with flame atomic absorption spectrometry for determination of trace cadmium in water samples. Talanta 80:980-984.
27. Mashayekhi HA, Abroomand-Azar P, Saber-Tehrani M, Hussain SW. 2010. Rapid determination of carbamazepine in human urine, plasma samples and water using DLLME followed by RP-LC. Chromatographia 71:517-521.
28. Mathieu D, Nony J, Phan-Tan-Luu R. 2000. NEMRODW (New Efficient Methodology for Research using Optimal Designs) Software. LPRAI: Marseille.
29. Melwanki MB, Fuh MR. 2008. Partitioned dispersive liquid-liquid microextraction. An approach for polar organic compounds extraction from aqueous samples. J. Chromatogr. A 1207:24-28.
30. Musshoff F, Trafkowski J, Kuepper U, Madea B. 2006. An automated and fully validated LC-MS/MS procedure for the simultaneous determination of 11 opioids used in palliative care, with 5 of their metabolites. J. Mass Spectrom. 41:633-640.
31. Nagaraju D, Huang SD. 2007. Determination of triazine herbicides in aqueous samples by dispersive liquid-liquid microextraction with gas chromatography-ion trap mass spectrometry. J. Chromatogr. A 1161:89-97.
32. Napoletano S, Montesano C, Compagnone D, Curini R, D'Ascenzo G, Roccia C, Sergi M. 2012. Determination of illicit drugs in urine and plasma by micro-SPE followed by HPLC-MS/MS. Chromatographia 75:55-63. DOI: 10.1007/s10337-011-2156-6.
33. OED (Observatorio Español de la Droga y las Toxicomanías). Informe anual 2012. Madrid: Ministerio de Sanidad, Servicios Sociales e Igualdad.
34. Pilgrim JL, Woodford N, Drummer OH. 2013. Cocaine in sudden and unexpected death: A review of 49 post-mortem cases. Forensic Sci. Int. 227:52-59.
35. Ramírez Fernández MM, Wille SMR, Kummer N, Di Fazio V, Ruyssinckx E, Samyn N. 2013. Quantitative analysis of 26 opioids, cocaine, and their metabolites in human blood by ultra performance liquid chromatography-tandem mass spectrometry. Ther. Drug Monit. 35:510-521.
36. Rezaee M, Assadi Y, Hosseini MRM, Aghaee E, Ahmadia F, Berijani S. 2006. Determination of organic compounds in water using dispersive liquid-liquid microextraction. J. Chromatogr. A 1116: 1-9.
37. Rezaee M, Yamini Y, Faraji M. 2010a. Evolution of dispersive liquid-liquid microextraction method. J. Chromatogr. A 1217:2342-2357.
38. Rezaee M, Yamini Y, Hojjati M, Faraju M. 2010b. Novel extraction method based on the dispersión of the extraction solvent for extraction of letrozole from biological fluids. Anal. Methods 2:1341-1345.
39. Rezaee M, Yamini Y, Khanchi A, Faraji M, Saleh A. 2010c. A simple and rapid new dispersive liquid-liquid microextraction based on solidification of floating organic drop combined with inductively coupled plasma-optical emission spectrometry for preconcentration and determination of aluminium in water samples. J. Hazardous Materials 178:766-770.
40. Rook EJ, Hillebrand, MJX, Rosing H, Van Ree JM, Beijnen JH. 2005. The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. B 824:213-221.
41. Ryan TP. 2007. Modern Experimental Design. John Wiley&Sons: Hoboken.
42. Saraji M, Boroujeni MK, Bidgoli AAH. 2011. Comparison of dispersive liquid-liquid microextraction and hollow fiber liquid-liquid-liquid microextraction for the determination of fentanyl, alfentanil, and sufentanil in water and biological fluids by high-performance liquid chromatography. Anal. Bioanal. Chem. 400: 2149-2158.
43. Shen G, Lee HK. 2002. Hollow fiber-protected liquid-phase microextraction of triazine herbicides. Anal. Chem. 74: 648-654.
44. UNODC. 2012. World Drug Report 2012. United Nations Publications: New York.
45. Williams J. 2008. The Declaration of Helsinki and Public Health. Bull. World Health Organ. 86: 650-651.
46. Xiong C, Ruan J, Cai Y, Tang Y. 2009. Extraction and determination of some psychotropic drugs in urine samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography. J. Pharm. Biomed. Anal. 49:572-578.
47. Xu H, Ding Z, Lv L, Song D, Feng YQ. 2009a. A novel dispersive liquid-liquid microextraction based on solidification of floating organic droplet method for determination of polycyclic aromatic hidrocarbons in aqueous samples. Anal. Chim. Acta 636: 28-33.
48. Xu H, Song D, Cui Y, Hu S, Yu QW, Feng YQ. 2009b. Analysis of hexanal and heptanal in human blood by simultaneous derivatization and dispersive liquid-liquid microextraction then LC-APCI-MS-MS. Chromatographia 70:775-781.
49. Zhang Y, Lee HK. 2012. Application of ultrasound-assisted emulsification microextraction based on applying low-density organic solvent for the determination of organochlorine pesticides in water samples. J. Chromatogr. A 1252:67-73.