Early donor-specific antibodies in lung transplantation: Risk factors and impact on survival

Journal of Heart and Lung Transplantation

Volumn 33, Issue 12, 2014, Pages 1255-1263

  Ius, Fabio ^a   Sommer, Wiebke ^a,b   Tudorache, Igor ^a   Kühn, Christian ^a   Avsar, Murat ^a   Siemeni, Thierry ^a   Salman, Jawad ^a   Hallensleben, Michael ^a   Kieneke, Daniela ^a   Greer, Mark ^a   Gottlieb, Jens ^a,b   Haverich, Axel ^a,b   Warnecke, Gregor ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b German Centre for Lung Research   (Germany)

Author keywords

acute rejection; BOS; donor specific HLA antibodies; lung transplantation; risk factors; survival

Indexed keywords

CYCLOSPORIN; DONOR SPECIFIC ANTIBODY; HLA ANTIBODY; IMMUNOGLOBULIN G; RITUXIMAB; TACROLIMUS; UNCLASSIFIED DRUG; ANTIIDIOTYPIC ANTIBODY; HLA ANTIGEN;

ACUTE GRAFT REJECTION; ADULT; ARTICLE; CEREBROVASCULAR ACCIDENT; DONOR; FEMALE; GRAFT SURVIVAL; HEART ATRIUM FIBRILLATION; HOSPITAL DISCHARGE; HUMAN; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PLASMAPHERESIS; PNEUMONIA; POSTOPERATIVE COMPLICATION; PRIMARY GRAFT DYSFUNCTION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RETRANSPLANTATION; RETROSPECTIVE STUDY; RISK FACTOR; SCORING SYSTEM; SURVIVAL; WOUND INFECTION; COMPARATIVE STUDY; GRAFT REJECTION; IMMUNOLOGY; LUNG; MIDDLE AGED; MULTIVARIATE ANALYSIS; SURVIVAL RATE; TREATMENT OUTCOME;

ADULT; ANTIBODIES, ANTI-IDIOTYPIC; FEMALE; GRAFT REJECTION; HLA ANTIGENS; HUMANS; LUNG; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; TISSUE DONORS; TREATMENT OUTCOME;

EID: 84923065107     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2014.06.015     Document Type: Article

References (31)

1. R.D. Yusen, J.D. Christie, and L.B. Edwards The registry of The International Society for Heart and Lung Transplantation: thirtieth adult lung and heart-lung transplant report-2013; focus theme: age J Heart Lung Transplant 32 2013 965 978
2. S.S. Weigt, A. DerHovanessian, and W.D. Wallace Bronchiolitis obliterans syndrome: The Achilles' heel of lung transplantation Semin Respir Crit Care Med 34 2013 336 351
3. J.L. Todd, and S.M. Palmer Bronchiolitis obliterans syndrome The final frontier for lung transplantation. Chest 140 2011 502 508
4. D.S. Nath, H.I. Basha, and T. Mohanakumar Anti-human leukocyte antibody induced autoimmunity: role in chronic rejection Curr Opin Organ Transplant 15 2010 16 20
5. N. Angaswamy, V. Tiriveedhi, and N.J. Sarma Interplay between immune responses to HLA and non-HLA self-antigens in allograft rejection Hum Immunol 74 2013 1478 1485
6. N. Angaswany, D. Saini, and S. Ramachandran Development of antibodies to human leukocyte antigen precedes development of antibodies to major histocompatibility class I-related chain A and are significantly associated with development of chronic rejection after human lung transplantation Hum Immunol 71 2010 560 565
7. T. Martinu, D.N. Howell, and S.M. Palmer Acute cellular rejection and humoral sensitization in lung transplant recipients Semin Respir Crit Care Med 31 2010 179 188
8. W. McManigle, E.N. Pavlisko, and T. Martinu Acute cellular and antibody-mediated allograft rejection Semin Respir Crit Care Med 34 2013 320 335
9. D. Hadjiliadis, C. Chaparro, and N.L. Reinsmoen Pre-transplant panel reactive antibody in lung transplant recipients is associated with significantly worse post-transplant survival in a multicenter study J Heart Lung Transplant 24 suppl 2005 S249 S254
10. A.L. Girnita, R. Duquesnoy, and S.A. Yousem HLA-specific antibodies are risk factors for lymphocytic bronchiolitis and chronic lung allograft dysfunction Am J Transplant 5 2005 131 138
11. A.S. Shah, L. Nwakanma, and C. Simpkins Pretransplant panel reactive antibodies in human lung transplantation: an analysis of over 10,000 patients Ann Thorac Surg 85 2008 1919 1924
12. A.A. Mangi, D.P. Mason, and E.R. Nowicki Predictors of acute rejection after lung transplantation Ann Thorac Surg 91 2011 1754 1762
13. D. Saini, J. Weber, and S. Ramachandran Alloimmunity-induced autoimmunity as a potential mechanism in The pathogenesis of chronic rejection of human lung allografts J Heart Lung Transplant 30 2011 624 631
14. L.D. Snyder, Z. Wang, and D.F. Chen Implications for human leukocyte antigen antibodies after lung transplantation: a 10 year experience in 441 patients Chest 144 2013 226 233
15. O. Brugiere, C. Suberbielle, and G. Thabut Lung transplantation in patients with pretransplantation donor-specific antibodies detected by Luminex assay Transplantation 95 2013 761 765
16. A. Bharat, E. Kuo, and N. Steward Immunological link between primary graft dysfunction and chronic lung allograft rejection Ann Thorac Surg 86 2008 189 197
17. R.R. Hachem, R.D. Yusen, and B.F. Meyers Anti-human leukocyte antigen antibodies and preemptive antibody-directed therapy after lung transplantation J Heart Lung Transplant 29 2010 973 980
18. L.J. Lobo, R.M. Aris, and J. Schmitz Donor-specific antibodies are associated with antibody-mediated rejection, acute cellular rejection, bronchiolitis obliterans syndrome, and cystic fibrosis after lung transplantation J Heart Lung Transplant 32 2013 70 77
19. C.A. Witt, J.P. Gaut, and R.D. Yusen Acute antibody-mediated rejection after lung transplantation J Heart Lung Transplant 32 2013 1034 1040
20. M.M. DeNicola, S.S. Weigt, and J.A. Belperio Pathologic findings in lung allografts with anti-HLA antibodies J Heart Lung Transplant 32 2013 326 332
21. A.R. Glanville Antibody-mediated rejection in lung transplantation: myth or reality? J Heart Lung Transplant 29 2010 395 400
22. F. Ius, C. Kuehn, and I. Tudorache Lung transplantation on cardiopulmonary support: venoarterial extracorporeal membrane oxygenation outperformed cardiopulmonary bypass J Thorac Cardiovasc Surg 144 2012 1510 1516
23. J.C. Lee, J.D. Christie, and S. Keshavjee Primary graft dysfunction: definition, risk factors, short- and long-term outcomes Semin Respir Crit Care Med 31 2010 161 171
24. S. Stewart, M.C. Fishbein, and G.I. Snell Revision of The 1996 working formulation for The standardization of nomenclature in The diagnosis of lung rejection J Heart Lung Transplant 26 2007 1229 1242
25. N. Lachmann, K. Todorova, and H. Schulze Luminex and its applications for solid organ transplantation, hematopoietic stem cell transplantation, and transfusion Transfus Med Hemother 40 2013 182 189
26. B.D. Tait, C. Süsal, and H.M. Gebel Consensus guidelines on The testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation Transplantation 95 2013 19 47
27. G. Warnecke, and A. Haverich Lung re-transplantation: review Curr Opin Organ Transplant 17 2012 485 489
28. J.M. Diamond, J.C. Lee, and S.M. Kawut Clinical risk factors for primary graft dysfunction after lung transplantation Am J Respir Crit Care Med 187 2013 527 534
29. N. Singh, J. Pirsch, and M. Samaniego Antibody-mediated rejection: treatment alternatives and outcomes Transplant Rev 23 2009 34 46
30. J. Gubensek, J. Buturovic-Ponivkar, and A. Kandus Plasma exchange and intravenous immunoglobulin in The treatment of antibody-mediated rejection after kidney transplantation: a single-center historic cohort study Transplant Proc 45 2013 1524 1527
31. M.N. Samano, L.M. Fernandes, and J.C.B. Baranauskas Risk factors and survival impact of primary graft dysfunction after lung transplantation in a single institution Transplant Proc 44 2012 2462 2468