Antibody-mediated rejection in lung transplantation: Myth or reality?

Journal of Heart and Lung Transplantation

Volumn 29, Issue 4, 2010, Pages 395-400

  Glanville, Allan R ^a  

^a ST VINCENT S HOSPITAL   (Australia)

Author keywords

antibody mediated; capillaritis; humoral; rejection

Indexed keywords

CD20 ANTIBODY; COMPLEMENT; CORTICOSTEROID; CYCLOPHOSPHAMIDE; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; THYMOCYTE ANTIBODY;

ACUTE GRAFT REJECTION; ANTIBODY PRODUCTION; ARTICLE; BLEEDING; BRONCHIOLITIS OBLITERANS; CAPILLARITIS; CARDIAC GRAFT REJECTION; CHRONIC GRAFT REJECTION; CLINICAL PROTOCOL; CORTICOSTEROID THERAPY; GRAFT DYSFUNCTION; GRAFT REJECTION; HEMOPTYSIS; HUMAN; HYPERACUTE GRAFT REJECTION; IMMUNOSUPPRESSIVE TREATMENT; LEUKOCYTE; LUNG EDEMA; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MEDICAL RESEARCH; MULTIPLE ORGAN FAILURE; ORGAN TRANSPLANTATION; PHENOTYPE; PLASMAPHERESIS; PRIORITY JOURNAL; TREATMENT FAILURE;

ANTIBODIES; ENDOTHELIUM; GRAFT REJECTION; HLA ANTIGENS; HUMANS; IMMUNITY, HUMORAL; LUNG TRANSPLANTATION; TRANSPLANTATION, HOMOLOGOUS;

EID: 77949543343     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2010.01.012     Document Type: Article

References (34)

1. Veith F.J., and Hagstrom J.W. Alveolar manifestations of rejection: an important cause of the poor results with human lung transplantation. Ann Surg 175 (1972) 336-348
2. Takemoto S.K., Zeevi A., Feng S., et al. National conference to assess antibody-mediated rejection in solid organ transplantation. Am J Transplant 4 (2004) 1033-1041
3. Terasaki P.I. Humoral theory of transplantation. Am J Transplant 3 (2003) 665-673
4. Yousem S.A., Berry G.J., Brunt E.M., et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Lung Rejection Study Group. The International Society for Heart Transplantation. J Heart Transplant 9 (1990) 593-601
5. Yousem S.A., Berry G.J., Cagle P.T., et al. Revision of the 1990 working formulation for the classification of pulmonary allograft rejection: Lung Rejection Study Group. J Heart Lung Transplant 15 (1996) 1-15
6. Stewart S., Fishbein M.C., Snell G.I., et al. Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection. J Heart Lung Transplant 26 (2007) 1229-1242
7. Shah A.S., Nwakanma L., Simpkins C., Williams J., Chang D.C., and Conte J.V. Pretransplant panel reactive antibodies in human lung transplantation: an analysis of over 10,000 patients. Ann Thorac Surg 85 (2008) 1919-1924
8. Frost A.E., Jammal C.T., and Cagle P.T. Hyperacute rejection following lung transplantation. Chest 110 (1996) 559-562
9. Bittner H.B., Dunitz J., Hertz M., Bolman III M.R., and Park S.J. Hyperacute rejection in single lung transplantation-case report of successful management by means of plasmapheresis and antithymocyte globulin treatment. Transplantation 71 (2001) 649-651
10. Masson E., Stern M., Chabod J., et al. Hyperacute rejection after lung transplantation caused by undetected low-titer anti-HLA antibodies. J Heart Lung Transplant 26 (2007) 642-645
11. de Jesus Peixoto Camargo J., Marcantonio Camargo S., Marcelo Schio S., Noguchi Machuca T., and Adelia Perin F. Hyperacute rejection after single lung transplantation: a case report. Transplant Proc 40 (2008) 867-869
12. Saint Martin G.A., Reddy V.B., Garrity E.R., et al. Humoral (antibody-mediated) rejection in lung transplantation. J Heart Lung Transplant 15 (1996) 1217-1222
13. Badesch D.B., Zamora M., Fullerton D., et al. Pulmonary capillaritis: a possible histologic form of acute pulmonary allograft rejection. J Heart Lung Transplant 17 (1998) 415-422
14. Astor T.L., Weill D., Cool C., Teitelbaum I., Schwarz M.I., and Zamora M.R. Pulmonary capillaritis in lung transplant recipients: treatment and effect on allograft function. J Heart Lung Transplant 24 (2005) 2091-2097
15. Girnita A.L., McCurry K.R., Yousem S.A., Pilewski J., and Zeevi A. Antibody-mediated rejection in lung transplantation: case reports. Clin Transpl (2006) 508-510
16. Astor T.L., Galantowicz M., Phillips A., Palafox J., and Baker P. Pulmonary capillaritis as a manifestation of acute humoral allograft rejection following infant lung transplantation. Am J Transplant 9 (2009) 409-412
17. Morrell M.R., Patterson G.A., Trulock E.P., and Hachem R.R. Acute antibody-mediated rejection after lung transplantation. J Heart Lung Transplant 28 (2009) 96-100
18. Jaramillo A., Fernandez F.G., Kuo E.Y., Trulock E.P., Patterson G.A., and Mohanakumar T. Immune mechanisms in the pathogenesis of bronchiolitis obliterans syndrome after lung transplantation. Pediatr Transplant 9 (2005) 84-93
19. Harjula A.L., Baldwin J.C., Glanville A.R., et al. Human leukocyte antigen compatibility in heart-lung transplantation. J Heart Transplant 6 (1987) 162-166
20. Schulman L.L., Weinberg A.D., McGregor C.C., Suciu-Foca N.M., and Itescu S. Influence of donor and recipient HLA locus mismatching on development of obliterative bronchiolitis after lung transplantation. Am J Respir Crit Care Med 163 (2001) 437-442
21. Chalermskulrat W., Neuringer I.P., Schmitz J.L., et al. Human leukocyte antigen mismatches predispose to the severity of bronchiolitis obliterans syndrome after lung transplantation. Chest 123 (2003) 1825-1831
22. Smith M.A., Sundaresan S., Mohanakumar T., et al. Effect of development of antibodies to HLA and cytomegalovirus mismatch on lung transplantation survival and development of bronchiolitis obliterans syndrome. J Thorac Cardiovasc Surg 116 (1998) 812-820
23. Sundaresan S., Mohanakumar T., Smith M.A., et al. HLA-A locus mismatches and development of antibodies to HLA after lung transplantation correlate with the development of bronchiolitis obliterans syndrome. Transplantation 65 (1998) 648-653
24. Quantz M.A., Bennett L.E., Meyer D.M., and Novick R.J. Does human leukocyte antigen matching influence the outcome of lung transplantation?. An analysis of 3,549 lung transplantations. J Heart Lung Transplant 19 (2000) 473-479
25. Smith J.D., Crisp S.J., Dunn M.J., Pomerance A., Yacoub M.H., and Rose M.L. Pre-transplant anti-epithelial cell antibodies and graft failure after single lung transplantation. Transpl Immunol 3 (1995) 68-73
26. Abdul-Karim A.B., Barnes A.D., Bevan I.S., et al. Anti-epithelial (anti-A549) antibodies: their nature, specificity and relevance to transplantation. Transpl Immunol 3 (1995) 192-202
27. Magro C.M., Deng A., Pope-Harman A., et al. Humorally mediated posttransplantation septal capillary injury syndrome as a common form of pulmonary allograft rejection: a hypothesis. Transplantation 74 (2002) 1273-1280
28. Magro C.M., Klinger D.M., Adams P.W., et al. Evidence that humoral allograft rejection in lung transplant patients is not histocompatibility antigen-related. Am J Transplant 3 (2003) 1264-1272
29. Magro C.M., Ross Jr. P., Kelsey M., Waldman W.J., and Pope-Harman A. Association of humoral immunity and bronchiolitis obliterans syndrome. Am J Transplant 3 (2003) 1155-1166
30. Magro C.M., Pope Harman A., Klinger D., et al. Use of C4d as a diagnostic adjunct in lung allograft biopsies. Am J Transplant 3 (2003) 1143-1154
31. Miller G.G., Destarac L., Zeevi A., et al. Acute humoral rejection of human lung allografts and elevation of C4d in bronchoalveolar lavage fluid. Am J Transplant 4 (2004) 1323-1330
32. Wallace W.D., Reed E.F., Ross D., Lassman C.R., and Fishbein M.C. C4d staining of pulmonary allograft biopsies: an immunoperoxidase study. J Heart Lung Transplant 24 (2005) 1565-1570
33. Magro C.M., Abbas A.E., Seilstad K., Pope-Harman A.L., Nadasdy T., and Ross Jr. P. C3d and the septal microvasculature as a predictor of chronic lung allograft dysfunction. Hum Immunol 67 (2006) 274-283
34. Westall G.P., Snell G.I., McLean C., Kotsimbos T., Williams T., and Magro C. C3d and C4d deposition early after lung transplantation. J Heart Lung Transplant 27 (2008) 722-728