Native nucleus pulposus tissue matrix promotes notochordal differentiation of human induced pluripotent stem cells with potential for treating intervertebral disc degeneration

Journal of Biomedical Materials Research - Part A

Volumn 103, Issue 3, 2015, Pages 1053-1059

  Liu, Yongxing ^a,b   Fu, Susan ^b   Rahaman, Mohamed N ^a   Mao, Jeremy J ^c   Bal, B Sonny ^d  

^a University of Missouri Rolla   (United States)

^b Innovative Elements LLC   (United States)

^c Columbia University ^*  (United States)

^d University of Missouri   (United States)

Author keywords

Cell therapy; Differentiation; Extracellular matrix; Human induced pluripotent stem cells; Intervertebral disc degeneration; Native nucleus pulposus tissue; Notochordal cells

Indexed keywords

CYTOLOGY; DIFFERENTIATION (CALCULUS); KERATIN; STEM CELLS; TISSUE;

CELL THERAPY; EXTRACELLULAR MATRICES; HUMAN-INDUCED PLURIPOTENT STEM CELLS; INTER-VERTEBRAL DISC DEGENERATION; NUCLEUS PULPOSUS;

CELLS;

COLLAGEN TYPE 2; CYTOKERATIN 18; CYTOKERATIN 8; DIFFERENTIATION ANTIGEN;

ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS TRANSPLANTATION; CELL THERAPY; CONTROLLED STUDY; EXPERIMENTAL PIG; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; MARKER GENE; NONHUMAN; NOTOCHORD; NUCLEAR REPROGRAMMING; NUCLEUS PULPOSUS; PLURIPOTENT STEM CELL; REGULATORY MECHANISM; SOMATIC CELL; TREATMENT OUTCOME; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CYTOLOGY; INTERVERTEBRAL DISC DEGENERATION; INTERVERTEBRAL DISK; METABOLISM; PIG;

ANIMALS; ANTIGENS, DIFFERENTIATION; CELL DIFFERENTIATION; CELL LINE; EXTRACELLULAR MATRIX; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; NOTOCHORD; SWINE;

EID: 84923039668     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35243     Document Type: Article

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