Statins improve the resolution of established murine venous thrombosis: Reductions in thrombus burden and vein wall scarring

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Kessinger, Chase W ^a   Kim, Jin Won ^a,b   Henke, Peter K ^c   Thompson, Brian ^a   McCarthy, Jason R ^a   Hara, Tetsuya ^a   Sillesen, Martin ^a   Margey, Ronan J P ^a   Libby, Peter ^d   Weissleder, Ralph ^a   Lin, Charles P ^a   Jaffer, Farouc A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Korea University College of Medicine   (South Korea)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; COLLAGEN; ENOXAPARIN; LIPID; MYELOPEROXIDASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; ROSUVASTATIN; THROMBOPLASTIN; ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; ANTITHROMBOCYTIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD CELL COUNT; BLOOD SAMPLING; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DRUG MECHANISM; DRUG RESPONSE; EXTRACELLULAR TRAP; FIBRINOLYSIS; IN VIVO STUDY; INFERIOR CAVA VEIN; LIPID BLOOD LEVEL; LOW DRUG DOSE; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; THROMBOCYTE AGGREGATION; VEIN INJURY; VENOUS STASIS; ANIMAL; CICATRIX; COMPLICATION; DRUG EFFECTS; PATHOPHYSIOLOGY; VEIN; VENOUS THROMBOSIS;

MURINAE; MUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTICOAGULANTS; CICATRIX; FIBRINOLYSIS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MICE; PLATELET AGGREGATION INHIBITORS; VEINS; VENOUS THROMBOSIS;

EID: 84923024059     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116621     Document Type: Article

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