Immediate antioxidant and antiplatelet effect of atorvastatin via inhibition of Nox2

Circulation

Volumn 126, Issue 1, 2012, Pages 92-103

  Pignatelli, Pasquale ^a   Carnevale, Roberto ^a   Pastori, Daniele ^a   Cangemi, Roberto ^a   Napoleone, Laura ^a   Bartimoccia, Simona ^a   Nocella, Cristina ^a   Basili, Stefania ^a   Violi, Francesco ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Antioxidants; Blood platelets; Hydroxymethylglutaryl CoA reductase inhibitors; Hypercholesterolemia; Statins; Thromboxanes

Indexed keywords

ATORVASTATIN; CHOLESTEROL; CREATININE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ISOPROSTANE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRIC OXIDE; PHOSPHOLIPASE A2; PROTEIN KINASE C; PROTEIN P47; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; THROMBOXANE A2; TRIACYLGLYCEROL; VASODILATOR STIMULATED PHOSPHOPROTEIN;

AGED; ANTICOAGULATION; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL INTAKE; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; DIET RESTRICTION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; MALE; MEDITERRANEAN DIET; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE; THROMBOCYTE ACTIVATION; TRIACYLGLYCEROL BLOOD LEVEL; URINALYSIS;

AGED; AGED, 80 AND OVER; ANTIOXIDANTS; COMBINED MODALITY THERAPY; DIET, MEDITERRANEAN; FEMALE; FOLLOW-UP STUDIES; HEPTANOIC ACIDS; HUMANS; HYPERCHOLESTEROLEMIA; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; NADPH OXIDASE; OXIDATIVE STRESS; PLATELET ACTIVATION; PYRROLES; TREATMENT OUTCOME;

EID: 84863613858     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.095554     Document Type: Article

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