메뉴 건너뛰기




Volumn 83, Issue 3, 2015, Pages 1056-1067

Phenotypic heterogeneity enables uropathogenic Escherichia coli to evade killing by antibiotics and serum complement

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMPICILLIN; COMPLEMENT COMPONENT C3B; NORFLOXACIN; ANTIINFECTIVE AGENT; COMPLEMENT COMPONENT C3;

EID: 84923010685     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.02725-14     Document Type: Article
Times cited : (33)

References (56)
  • 1
    • 0036851258 scopus 로고    scopus 로고
    • Chronic bacterial infections: living with unwanted guests
    • Young D, Hussell T, Dougan G. 2002. Chronic bacterial infections: living with unwanted guests. Nat Immunol 3:1026-1032. http://dx.doi.org/10.1038/ni1102-1026.
    • (2002) Nat Immunol , vol.3 , pp. 1026-1032
    • Young, D.1    Hussell, T.2    Dougan, G.3
  • 2
    • 79151475628 scopus 로고    scopus 로고
    • The complement system
    • Sarma JV, Ward PA. 2011. The complement system. Cell Tissue Res 343:227-235. http://dx.doi.org/10.1007/s00441-010-1034-0.
    • (2011) Cell Tissue Res , vol.343 , pp. 227-235
    • Sarma, J.V.1    Ward, P.A.2
  • 3
    • 33846917258 scopus 로고    scopus 로고
    • Expression of terminal complement components by human keratinocytes
    • Timar KK, Dallos A, Kiss M, Husz S, Bos JD, Asghar SS. 2007. Expression of terminal complement components by human keratinocytes. Mol Immunol 44:2578-2586. http://dx.doi.org/10.1016/j.molimm.2006.12.014.
    • (2007) Mol Immunol , vol.44 , pp. 2578-2586
    • Timar, K.K.1    Dallos, A.2    Kiss, M.3    Husz, S.4    Bos, J.D.5    Asghar, S.S.6
  • 4
    • 84861144335 scopus 로고    scopus 로고
    • Loss of outer membrane protein C in Escherichia coli contributes to both antibiotic resistance and escaping antibody-dependent bactericidal activity
    • Liu YF, Yan JJ, Lei HY, Teng CH, Wang MC, Tseng CC, Wu JJ. 2012. Loss of outer membrane protein C in Escherichia coli contributes to both antibiotic resistance and escaping antibody-dependent bactericidal activity. Infect Immun 80:1815-1822. http://dx.doi.org/10.1128/IAI.06395-11.
    • (2012) Infect Immun , vol.80 , pp. 1815-1822
    • Liu, Y.F.1    Yan, J.J.2    Lei, H.Y.3    Teng, C.H.4    Wang, M.C.5    Tseng, C.C.6    Wu, J.J.7
  • 5
    • 84857128099 scopus 로고    scopus 로고
    • Bacterial capsules and evasion ofimmuneresponses
    • John Wiley & Sons, Ltd., Chichester, United Kingdom
    • Merino S, Tomas J. 2010. Bacterial capsules and evasion ofimmuneresponses. In Encyclopedia of life sciences. John Wiley & Sons, Ltd., Chichester, United Kingdom. http://dx.doi.org/10.1002/9780470015902.a0000957.pub3.
    • (2010) Encyclopedia of life sciences
    • Merino, S.1    Tomas, J.2
  • 7
    • 84899983124 scopus 로고    scopus 로고
    • Bacterial self-defense: how Escherichia coli evades serum killing
    • Miajlovic H, Smith SG. 2014. Bacterial self-defense: how Escherichia coli evades serum killing. FEMS Microbiol Lett 354:1-9. http://dx.doi.org/10.1111/1574-6968.12419.
    • (2014) FEMS Microbiol Lett , vol.354 , pp. 1-9
    • Miajlovic, H.1    Smith, S.G.2
  • 8
    • 84890811277 scopus 로고    scopus 로고
    • Response of extraintestinal pathogenic Escherichia coli to human serum reveals a protective role for Rcs-regulated exopolysaccharide colanic acid
    • Miajlovic H, Cooke NM, Moran GP, Rogers TR, Smith SG. 2014. Response of extraintestinal pathogenic Escherichia coli to human serum reveals a protective role for Rcs-regulated exopolysaccharide colanic acid. Infect Immun 82:298-305. http://dx.doi.org/10.1128/IAI.00800-13.
    • (2014) Infect Immun , vol.82 , pp. 298-305
    • Miajlovic, H.1    Cooke, N.M.2    Moran, G.P.3    Rogers, T.R.4    Smith, S.G.5
  • 9
    • 84899527395 scopus 로고    scopus 로고
    • Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli
    • Sarkar S, Ulett GC, Totsika M, Phan MD, Schembri MA. 2014. Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli. PLoS One 9:e94786. http://dx.doi.org/10.1371/journal.pone.0094786.
    • (2014) PLoS One , vol.9
    • Sarkar, S.1    Ulett, G.C.2    Totsika, M.3    Phan, M.D.4    Schembri, M.A.5
  • 10
    • 84883809384 scopus 로고    scopus 로고
    • Structural modifications of bacterial lipopolysaccharide that facilitate gram-negative bacteria evasion of host innate immunity
    • Matsuura M. 2013. Structural modifications of bacterial lipopolysaccharide that facilitate gram-negative bacteria evasion of host innate immunity. Front Immunol 4:109. http://dx.doi.org/10.3389/fimmu.2013.00109.
    • (2013) Front Immunol , vol.4 , pp. 109
    • Matsuura, M.1
  • 11
    • 0002727855 scopus 로고
    • Kinetics of the bactericidal action of normal serum on gram-negative bacteria
    • Davis SD, Wedgwood RJ. 1965. Kinetics of the bactericidal action of normal serum on gram-negative bacteria. J Immunol 95:75-79.
    • (1965) J Immunol , vol.95 , pp. 75-79
    • Davis, S.D.1    Wedgwood, R.J.2
  • 12
    • 70449185467 scopus 로고
    • Lysis of gram-negative bacteria by serum
    • Rowley D, Wardlaw AC. 1958. Lysis of gram-negative bacteria by serum. J Gen Microbiol 18:529-533. http://dx.doi.org/10.1099/00221287-18-2-529.
    • (1958) J Gen Microbiol , vol.18 , pp. 529-533
    • Rowley, D.1    Wardlaw, A.C.2
  • 13
    • 0019418533 scopus 로고
    • Susceptibility of Pseudomonas aeruginosa to serum bactericidal activity. A comparison of three methods with clinical correlations
    • DeMatteo CS, Hammer MC, Baltch AL, Smith RP, Sutphen NT, Michelsen PB. 1981. Susceptibility of Pseudomonas aeruginosa to serum bactericidal activity. A comparison of three methods with clinical correlations. J Lab Clin Med 98:511-518.
    • (1981) J Lab Clin Med , vol.98 , pp. 511-518
    • DeMatteo, C.S.1    Hammer, M.C.2    Baltch, A.L.3    Smith, R.P.4    Sutphen, N.T.5    Michelsen, P.B.6
  • 14
    • 0018869926 scopus 로고
    • Analysis of outer membrane components of Escherichia coli ML308 225 and of a serum-resistant mutant
    • Tee GL, Scott GK. 1980. Analysis of outer membrane components of Escherichia coli ML308 225 and of a serum-resistant mutant. Infect Immun 28:387-392.
    • (1980) Infect Immun , vol.28 , pp. 387-392
    • Tee, G.L.1    Scott, G.K.2
  • 15
    • 33645021029 scopus 로고    scopus 로고
    • Logarithmic phase Escherichia coli K1 efficiently avoids serum killing by promoting C4bp-mediated C3b and C4b degradation
    • Wooster DG, Maruvada R, Blom AM, Prasadarao NV. 2006. Logarithmic phase Escherichia coli K1 efficiently avoids serum killing by promoting C4bp-mediated C3b and C4b degradation. Immunology 117:482-493. http://dx.doi.org/10.1111/j.1365-2567.2006.02323.x.
    • (2006) Immunology , vol.117 , pp. 482-493
    • Wooster, D.G.1    Maruvada, R.2    Blom, A.M.3    Prasadarao, N.V.4
  • 16
    • 16244366759 scopus 로고    scopus 로고
    • Role of YadA, Ail, and lipopolysaccharide in serum resistance of Yersinia enterocolitica serotype O:3
    • Biedzka-Sarek M, Venho R, Skurnik M. 2005. Role of YadA, Ail, and lipopolysaccharide in serum resistance of Yersinia enterocolitica serotype O:3. Infect Immun 73:2232-2244. http://dx.doi.org/10.1128/IAI.73.4.2232-2244.2005.
    • (2005) Infect Immun , vol.73 , pp. 2232-2244
    • Biedzka-Sarek, M.1    Venho, R.2    Skurnik, M.3
  • 17
    • 81755161196 scopus 로고    scopus 로고
    • Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody
    • Dalia AB, Weiser JN. 2011. Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody. Cell Host Microbe 10:486-496. http://dx.doi.org/10.1016/j.chom.2011.09.009.
    • (2011) Cell Host Microbe , vol.10 , pp. 486-496
    • Dalia, A.B.1    Weiser, J.N.2
  • 18
    • 77951231961 scopus 로고    scopus 로고
    • Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics
    • Blango MG, Mulvey MA. 2010. Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics. Antimicrob Agents Chemother 54:1855-1863. http://dx.doi.org/10.1128/AAC.00014-10.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 1855-1863
    • Blango, M.G.1    Mulvey, M.A.2
  • 19
    • 17144416850 scopus 로고    scopus 로고
    • Persister cells and the riddle of biofilm survival
    • Lewis K. 2005. Persister cells and the riddle of biofilm survival. Biochemistry 70:267-274. http://dx.doi.org/10.1007/s10541-005-0111-6.
    • (2005) Biochemistry , vol.70 , pp. 267-274
    • Lewis, K.1
  • 20
    • 77957947243 scopus 로고    scopus 로고
    • Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis
    • Mulcahy LR, Burns JL, Lory S, Lewis K. 2010. Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis. J Bacteriol 192:6191-6199. http://dx.doi.org/10.1128/JB.01651-09.
    • (2010) J Bacteriol , vol.192 , pp. 6191-6199
    • Mulcahy, L.R.1    Burns, J.L.2    Lory, S.3    Lewis, K.4
  • 21
    • 73849102829 scopus 로고    scopus 로고
    • Patients with long-term oral carriage harbor high-persister mutants of Candida albicans
    • Lafleur MD, Qi Q, Lewis K. 2010. Patients with long-term oral carriage harbor high-persister mutants of Candida albicans. Antimicrob Agents Chemother 54:39-44. http://dx.doi.org/10.1128/AAC.00860-09.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 39-44
    • Lafleur, M.D.1    Qi, Q.2    Lewis, K.3
  • 22
    • 79953000787 scopus 로고    scopus 로고
    • Persisting clones of Escherichia coli isolates from recurrent urinary tract infection in men and women
    • Skjot-Rasmussen L, Hammerum AM, Jakobsen L, Lester CH, Larsen P, Frimodt-Moller N. 2011. Persisting clones of Escherichia coli isolates from recurrent urinary tract infection in men and women. J Med Microbiol 60:550-554. http://dx.doi.org/10.1099/jmm.0.026963-0.
    • (2011) J Med Microbiol , vol.60 , pp. 550-554
    • Skjot-Rasmussen, L.1    Hammerum, A.M.2    Jakobsen, L.3    Lester, C.H.4    Larsen, P.5    Frimodt-Moller, N.6
  • 23
    • 38049053061 scopus 로고    scopus 로고
    • Detection of intracellular bacterial communities in human urinary tract infection
    • Rosen DA, Hooton TM, Stamm WE, Humphrey PA, Hultgren SJ. 2007. Detection of intracellular bacterial communities in human urinary tract infection. PLoS Med 4:e329. http://dx.doi.org/10.1371/journal.pmed.0040329.
    • (2007) PLoS Med , vol.4
    • Rosen, D.A.1    Hooton, T.M.2    Stamm, W.E.3    Humphrey, P.A.4    Hultgren, S.J.5
  • 24
    • 45549104015 scopus 로고    scopus 로고
    • Multidrug tolerance of biofilms and persister cells
    • Lewis K. 2008. Multidrug tolerance of biofilms and persister cells. Curr Top Microbiol Immunol 322:107-131. http://dx.doi.org/10.1007/978-3-540-75418-3_6.
    • (2008) Curr Top Microbiol Immunol , vol.322 , pp. 107-131
    • Lewis, K.1
  • 26
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko KA, Wanner BL. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 97:6640-6645. http://dx.doi.org/10.1073/pnas.120163297.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 27
    • 37849046403 scopus 로고    scopus 로고
    • Translation initiation region sequence preferences in Escherichia coli
    • Vimberg V, Tats A, Remm M, Tenson T. 2007. Translation initiation region sequence preferences in Escherichia coli. BMC Mol Biol 8:100. http://dx.doi.org/10.1186/1471-2199-8-100.
    • (2007) BMC Mol Biol , vol.8 , pp. 100
    • Vimberg, V.1    Tats, A.2    Remm, M.3    Tenson, T.4
  • 28
    • 0034924241 scopus 로고    scopus 로고
    • Determination of minimum inhibitory concentrations
    • Andrews JM. 2001. Determination of minimum inhibitory concentrations. J Antimicrob Chemother 48(Suppl 1):S5-S16. http://dx.doi.org/10.1093/jac/48.suppl_1.5.
    • (2001) J Antimicrob Chemother , vol.48 , pp. S5-S16
    • Andrews, J.M.1
  • 31
    • 84877817268 scopus 로고    scopus 로고
    • The Cpx stress response system potentiates the fitness and virulence of uropathogenic Escherichia coli
    • Debnath I, Norton JP, Barber AE, Ott EM, Dhakal BK, Kulesus RR, Mulvey MA. 2013. The Cpx stress response system potentiates the fitness and virulence of uropathogenic Escherichia coli. Infect Immun 81:1450-1459. http://dx.doi.org/10.1128/IAI.01213-12.
    • (2013) Infect Immun , vol.81 , pp. 1450-1459
    • Debnath, I.1    Norton, J.P.2    Barber, A.E.3    Ott, E.M.4    Dhakal, B.K.5    Kulesus, R.R.6    Mulvey, M.A.7
  • 32
    • 33846920093 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a simple model to study phenotypic and genetic virulence determinants of extraintestinal pathogenic Escherichia coli
    • Diard M, Baeriswyl S, Clermont O, Gouriou S, Picard B, Taddei F, Denamur E, Matic I. 2007. Caenorhabditis elegans as a simple model to study phenotypic and genetic virulence determinants of extraintestinal pathogenic Escherichia coli. Microbes Infect 9:214-223. http://dx.doi.org/10.1016/j.micinf.2006.11.009.
    • (2007) Microbes Infect , vol.9 , pp. 214-223
    • Diard, M.1    Baeriswyl, S.2    Clermont, O.3    Gouriou, S.4    Picard, B.5    Taddei, F.6    Denamur, E.7    Matic, I.8
  • 33
    • 67650266226 scopus 로고    scopus 로고
    • Bacteriolytic activity of the alternative pathway of complement differs kinetically from the classical pathway
    • Kilpi MK, Atosuo JT, Lilius EM. 2009. Bacteriolytic activity of the alternative pathway of complement differs kinetically from the classical pathway. Dev Comp Immunol 33:1102-1110. http://dx.doi.org/10.1016/j.dci.2009.06.007.
    • (2009) Dev Comp Immunol , vol.33 , pp. 1102-1110
    • Kilpi, M.K.1    Atosuo, J.T.2    Lilius, E.M.3
  • 34
    • 50349141358 scopus 로고
    • Treatment of staphylococcal infections with penicillin by intermittent sterilisation
    • Bigger J. 1944. Treatment of staphylococcal infections with penicillin by intermittent sterilisation. Lancet 244:497-500. http://dx.doi.org/10.1016/S0140-6736(00)74210-3.
    • (1944) Lancet , vol.244 , pp. 497-500
    • Bigger, J.1
  • 35
    • 0020590028 scopus 로고
    • hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
    • Moyed HS, Bertrand KP. 1983. hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J Bacteriol 155:768-775.
    • (1983) J Bacteriol , vol.155 , pp. 768-775
    • Moyed, H.S.1    Bertrand, K.P.2
  • 36
    • 4644343922 scopus 로고    scopus 로고
    • Bacterial persistence as a phenotypic switch
    • Balaban NQ, Merrin J, Chait R, Kowalik L, Leibler S. 2004. Bacterial persistence as a phenotypic switch. Science 305:1622-1625. http://dx.doi.org/10.1126/science.1099390.
    • (2004) Science , vol.305 , pp. 1622-1625
    • Balaban, N.Q.1    Merrin, J.2    Chait, R.3    Kowalik, L.4    Leibler, S.5
  • 37
    • 10044266575 scopus 로고    scopus 로고
    • Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
    • Keren I, Shah D, Spoering A, Kaldalu N, Lewis K. 2004. Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J Bacteriol 186:8172-8180. http://dx.doi.org/10.1128/JB.186.24.8172-8180.2004.
    • (2004) J Bacteriol , vol.186 , pp. 8172-8180
    • Keren, I.1    Shah, D.2    Spoering, A.3    Kaldalu, N.4    Lewis, K.5
  • 38
    • 79955886933 scopus 로고    scopus 로고
    • Metabolite-enabled eradication of bacterial persisters by aminoglycosides
    • Allison KR, Brynildsen MP, Collins JJ. 2011. Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature 473:216-220. http://dx.doi.org/10.1038/nature10069.
    • (2011) Nature , vol.473 , pp. 216-220
    • Allison, K.R.1    Brynildsen, M.P.2    Collins, J.J.3
  • 39
    • 77954369912 scopus 로고    scopus 로고
    • The frequency of persisters in Escherichia coli reflects the kinetics of awakening from dormancy
    • Jõers A, Kaldalu N, Tenson T. 2010. The frequency of persisters in Escherichia coli reflects the kinetics of awakening from dormancy. J Bacteriol 192:3379-3384. http://dx.doi.org/10.1128/JB.00056-10.
    • (2010) J Bacteriol , vol.192 , pp. 3379-3384
    • Jõers, A.1    Kaldalu, N.2    Tenson, T.3
  • 40
    • 43549091825 scopus 로고    scopus 로고
    • Cell division in Escherichia coli cultures monitored at single cell resolution
    • Roostalu J, Joers A, Luidalepp H, Kaldalu N, Tenson T. 2008. Cell division in Escherichia coli cultures monitored at single cell resolution. BMC Microbiol 8:68. http://dx.doi.org/10.1186/1471-2180-8-68.
    • (2008) BMC Microbiol , vol.8 , pp. 68
    • Roostalu, J.1    Joers, A.2    Luidalepp, H.3    Kaldalu, N.4    Tenson, T.5
  • 41
    • 84879031775 scopus 로고    scopus 로고
    • Dormancy is not necessary or sufficient for bacterial persistence
    • Orman MA, Brynildsen MP. 2013. Dormancy is not necessary or sufficient for bacterial persistence. Antimicrob Agents Chemother 57:3230-3239. http://dx.doi.org/10.1128/AAC.00243-13.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3230-3239
    • Orman, M.A.1    Brynildsen, M.P.2
  • 42
    • 41349119880 scopus 로고    scopus 로고
    • Stochastic switching as a survival strategy in fluctuating environments
    • Acar M, Mettetal JT, van Oudenaarden A. 2008. Stochastic switching as a survival strategy in fluctuating environments. Nat Genet 40:471-475. http://dx.doi.org/10.1038/ng.110.
    • (2008) Nat Genet , vol.40 , pp. 471-475
    • Acar, M.1    Mettetal, J.T.2    van Oudenaarden, A.3
  • 43
    • 79954483631 scopus 로고    scopus 로고
    • Optimal resting-growth strategies of microbial populations in fluctuating environments
    • Geisel N, Vilar JM, Rubi JM. 2011. Optimal resting-growth strategies of microbial populations in fluctuating environments. PLoS One 6:e18622. http://dx.doi.org/10.1371/journal.pone.0018622.
    • (2011) PLoS One , vol.6
    • Geisel, N.1    Vilar, J.M.2    Rubi, J.M.3
  • 46
    • 77955939137 scopus 로고    scopus 로고
    • The Rcs phosphorelay: more than just a two-component pathway
    • Clarke DJ. 2010. The Rcs phosphorelay: more than just a two-component pathway. Future Microbiol 5:1173-1184. http://dx.doi.org/10.2217/fmb.10.83.
    • (2010) Future Microbiol , vol.5 , pp. 1173-1184
    • Clarke, D.J.1
  • 47
    • 77955628762 scopus 로고    scopus 로고
    • Persister cells
    • Lewis K. 2010. Persister cells. Annu Rev Microbiol 64:357-372. http://dx.doi.org/10.1146/annurev.micro.112408.134306.
    • (2010) Annu Rev Microbiol , vol.64 , pp. 357-372
    • Lewis, K.1
  • 48
    • 65349138252 scopus 로고    scopus 로고
    • Synergy between type 1 fimbriae expression and C3 opsonisation increases internalisation of Escherichia coli by human tubular epithelial cells
    • Li K, Zhou W, Hong Y, Sacks SH, Sheerin NS. 2009. Synergy between type 1 fimbriae expression and C3 opsonisation increases internalisation of Escherichia coli by human tubular epithelial cells. BMC Microbiol 9:64. http://dx.doi.org/10.1186/1471-2180-9-64.
    • (2009) BMC Microbiol , vol.9 , pp. 64
    • Li, K.1    Zhou, W.2    Hong, Y.3    Sacks, S.H.4    Sheerin, N.S.5
  • 49
    • 80053236888 scopus 로고    scopus 로고
    • Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages
    • Bokil NJ, Totsika M, Carey AJ, Stacey KJ, Hancock V, Saunders BM, Ravasi T, Ulett GC, Schembri MA, Sweet MJ. 2011. Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages. Immunobiology 216:1164-1171. http://dx.doi.org/10.1016/j.imbio.2011.05.011.
    • (2011) Immunobiology , vol.216 , pp. 1164-1171
    • Bokil, N.J.1    Totsika, M.2    Carey, A.J.3    Stacey, K.J.4    Hancock, V.5    Saunders, B.M.6    Ravasi, T.7    Ulett, G.C.8    Schembri, M.A.9    Sweet, M.J.10
  • 50
    • 79960941334 scopus 로고    scopus 로고
    • The cost of virulence: retarded growth of Salmonella typhimurium cells expressing type III secretion system 1
    • Sturm A, Heinemann M, Arnoldini M, Benecke A, Ackermann M, Benz M, Dormann J, Hardt WD. 2011. The cost of virulence: retarded growth of Salmonella typhimurium cells expressing type III secretion system 1. PLoS Pathog 7:e1002143. http://dx.doi.org/10.1371/journal.ppat.1002143.
    • (2011) PLoS Pathog , vol.7
    • Sturm, A.1    Heinemann, M.2    Arnoldini, M.3    Benecke, A.4    Ackermann, M.5    Benz, M.6    Dormann, J.7    Hardt, W.D.8
  • 51
    • 84896987890 scopus 로고    scopus 로고
    • Overexpression of MexCD-OprJ reduces Pseudomonas aeruginosa virulence by increasing its susceptibility to complement-mediated killing
    • Martinez-Ramos I, Mulet X, Moya B, Barbier M, Oliver A, Alberti S. 2014. Overexpression of MexCD-OprJ reduces Pseudomonas aeruginosa virulence by increasing its susceptibility to complement-mediated killing. Antimicrob Agents Chemother 58:2426-2429. http://dx.doi.org/10.1128/AAC.02012-13.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2426-2429
    • Martinez-Ramos, I.1    Mulet, X.2    Moya, B.3    Barbier, M.4    Oliver, A.5    Alberti, S.6
  • 52
    • 84908628086 scopus 로고    scopus 로고
    • Identification of Acinetobacter baumannii serum-associated antibiotic efflux pump inhibitors
    • Blanchard C, Barnett P, Perlmutter J, Dunman PM. 2014. Identification of Acinetobacter baumannii serum-associated antibiotic efflux pump inhibitors. Antimicrob Agents Chemother 58:6360-6370. http://dx.doi.org/10.1128/AAC.03535-14.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 6360-6370
    • Blanchard, C.1    Barnett, P.2    Perlmutter, J.3    Dunman, P.M.4
  • 53
    • 0027528537 scopus 로고
    • Activity of the carbapenem panipenem and role of the OprD (D2) protein in its diffusion through the Pseudomonas aeruginosa outer membrane
    • Fukuoka T, Ohya S, Narita T, Katsuta M, Iijima M, Masuda N, Yasuda H, Trias J, Nikaido H. 1993. Activity of the carbapenem panipenem and role of the OprD (D2) protein in its diffusion through the Pseudomonas aeruginosa outer membrane. Antimicrob Agents Chemother 37:322-327. http://dx.doi.org/10.1128/AAC.37.2.322.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 322-327
    • Fukuoka, T.1    Ohya, S.2    Narita, T.3    Katsuta, M.4    Iijima, M.5    Masuda, N.6    Yasuda, H.7    Trias, J.8    Nikaido, H.9
  • 55
    • 84892181925 scopus 로고    scopus 로고
    • Internalization of Salmonella by macrophages induces formation of nonreplicating persisters
    • Helaine S, Cheverton AM, Watson KG, Faure LM, Matthews SA, Holden DW. 2014. Internalization of Salmonella by macrophages induces formation of nonreplicating persisters. Science 343:204-208. http://dx.doi.org/10.1126/science.1244705.
    • (2014) Science , vol.343 , pp. 204-208
    • Helaine, S.1    Cheverton, A.M.2    Watson, K.G.3    Faure, L.M.4    Matthews, S.A.5    Holden, D.W.6
  • 56
    • 84908456444 scopus 로고    scopus 로고
    • Phenotypic variation of salmonella in host tissues delays eradication by antimicrobial chemotherapy
    • Claudi B, Sprote P, Chirkova A, Personnic N, Zankl J, Schurmann N, Schmidt A, Bumann D. 2014. Phenotypic variation of salmonella in host tissues delays eradication by antimicrobial chemotherapy. Cell 158:722-733. http://dx.doi.org/10.1016/j.cell.2014.06.045.
    • (2014) Cell , vol.158 , pp. 722-733
    • Claudi, B.1    Sprote, P.2    Chirkova, A.3    Personnic, N.4    Zankl, J.5    Schurmann, N.6    Schmidt, A.7    Bumann, D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.