Mechanochemical Stimulation of MCF7 Cells with Rod-Shaped Fe-Au Janus Particles Induces Cell Death Through Paradoxical Hyperactivation of ERK

Advanced Healthcare Materials

Volumn 4, Issue 3, 2015, Pages 395-404

  Kilinc, Devrim ^a   Lesniak, Anna ^a   Rashdan, Suad A ^a,b   Gandhi, Dhruv ^a   Blasiak, Agata ^a   Fannin, Paul C ^c   von Kriegsheim, Alex ^a   Kolch, Walter ^a   Lee, Gil U ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF BAHRAIN   (Bahrain)

^c TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Active targeting; Cancer; ErbB receptors; Heregulin; Magnetic hyperthermia

Indexed keywords

BINARY ALLOYS; CELL CULTURE; CELL DEATH; DISEASES; GOLD COATINGS; IRON ALLOYS; MAGNETISM; NANOPARTICLES; NANORODS; PHOSPHORYLATION;

ACTIVE TARGETING; CANCER; ERBB RECEPTORS; HEREGULIN; MAGNETIC HYPERTHERMIA;

GOLD ALLOYS;

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; GOLD; IRON GOLD NANOROD; MACROGOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; NANOROD; NEU DIFFERENTIATION FACTOR; UNCLASSIFIED DRUG; VEMURAFENIB; B RAF KINASE; BRAF PROTEIN, HUMAN; ERBB2 PROTEIN, HUMAN; INDOLE DERIVATIVE; IRON; NANOTUBE; SULFONAMIDE;

ARTICLE; BREAST ADENOCARCINOMA; BREAST CANCER CELL LINE; CELL DEATH; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG COATING; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; LIGAND BINDING; MAGNETIC HYPERTHERMIA; MCF 7 CELL LINE; MDA MB 231 CELL LINE; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; MICROFLUIDICS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; FEMALE; MAGNETIC FIELD; METABOLISM; MICROFLUIDIC ANALYSIS; MOLECULARLY TARGETED THERAPY; NANOTECHNOLOGY; PHOSPHORYLATION; PROCEDURES; STIMULATION; THERMOTHERAPY;

CELL DEATH; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GOLD; HUMANS; HYPERTHERMIA, INDUCED; INDOLES; IRON; MAGNETIC FIELDS; MCF-7 CELLS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MOLECULAR TARGETED THERAPY; NANOTECHNOLOGY; NANOTUBES; NEUREGULIN-1; PHOSPHORYLATION; PHYSICAL STIMULATION; PROTO-ONCOGENE PROTEINS B-RAF; RECEPTOR, ERBB-2; SULFONAMIDES;

EID: 84922998554     PISSN: 21922640     EISSN: 21922659     Source Type: Journal    
DOI: 10.1002/adhm.201400391     Document Type: Article

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