Dynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 35, 2012, Pages 13984-13989

  Hiroshima, Michio ^a   Saeki, Yuko ^b   Okada Hatakeyama, Mariko ^b   Sako, Yasushi ^a  

^a RIKEN   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

Cell signaling; Epidermal growth factors; Ligand receptor interaction

Indexed keywords

DIMER; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; FLUORESCENT DYE; LIGAND; MONOMER; NEU DIFFERENTIATION FACTOR; RECEPTOR;

ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CELL STRAIN MCF 7; CELL SURFACE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DIMERIZATION; DISSOCIATION; EQUILIBRIUM CONSTANT; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR IMAGING; MOLECULE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CELL MEMBRANE; DIMERIZATION; FEMALE; FLUORESCENT DYES; HELA CELLS; HUMANS; KINETICS; LIGANDS; MICROSCOPY, FLUORESCENCE; MODELS, CHEMICAL; NEUREGULIN-1; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-3; RECEPTORS, CELL SURFACE; RHODAMINES; SIGNAL TRANSDUCTION;

EID: 84865553091     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200464109     Document Type: Article

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