Impairment of glutamate signaling in mouse central nervous system neurons in vitro by tri-ortho-cresyl phosphate at noncytotoxic concentrations

Toxicological Sciences

Volumn 142, Issue 1, 2014, Pages 274-284

  Hausherr, Vanessa ^a   Thriel, Christoph van ^a   Krug, Anne ^b   Leist, Marcel ^b   Schöbel, Nicole ^a,c  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Aerotoxic syndrome; Glutamate signaling; Neurite outgrowth inhibition; Neurotoxicity; Tri ortho cresyl phosphate

Indexed keywords

GLUTAMIC ACID; TRI ORTHO CRESYL PHOSPHATE; POLLUTANT; TRI-O-CRESYL PHOSPHATE; TRICRESYL PHOSPHATE;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CELL; CELL CULTURE; CELL ISOLATION; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOTOXICITY; EC50; EMBRYO; GLUTAMATERGIC SYNAPSE; IN VITRO STUDY; MOUSE; NERVE CELL NECROSIS; NERVE FIBER GROWTH; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; POSTSYNAPTIC POTENTIAL; SIGNAL TRANSDUCTION; ANIMAL; BRAIN CORTEX; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; EMBRYOLOGY; IMMUNOHISTOCHEMISTRY; INBRED MOUSE STRAIN; METABOLISM; NERVE CELL; NEURITE; PATHOLOGY; POLLUTANT; PRIMARY CELL CULTURE; TOXICITY;

ANIMALS; CELL SURVIVAL; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; MICE, INBRED STRAINS; NEURITES; NEURONS; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; TRITOLYL PHOSPHATES;

EID: 84922977357     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu174     Document Type: Article

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