Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis

Journal of Hepatology

Volumn 62, Issue 3, 2015, Pages 664-672

  De Tayrac, Marie ^a,b,c   Roth, Marie Paule ^d,e,f   Jouanolle, Anne Marie ^c   Coppin, Hélène ^d,e,f   Le Gac, Gérald ^g,h   Piperno, Alberto ⁱ   Férec, Claude ^g,h   Pelucchi, Sara ⁱ   Scotet, Virginie ^g,h   Bardou Jacquet, Edouard ^c,d   Ropert, Martine ^c   Bouvet, Régis ^c,j   Génin, Emmanuelle ^g   Mosser, Jean ^a,b,c   Deugnier, Yves ^c,d  

^a UNIVERSITÉ DE RENNES 1   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c RENNES UNIVERSITY HOSPITAL   (France)

^d INSERM   (France)

^e CNRS   (France)

^f UNIVERSITÉ PAUL SABATIER   (France)

^g UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^h ETABLISSEMENT FRANÇAIS DU SANG   (France)

ⁱ SAN GERARDO HOSPITAL   (Italy)

^j Liver Unit and French Reference Centre for Rare Iron Overload Diseases of Genetic Origin ^*  (France)

more..

Author keywords

GWAS; HFE hemochromatosis; Transferrin

Indexed keywords

FERRITIN; HFE PROTEIN; IRON; TRANSFERRIN; HFE PROTEIN, HUMAN; HLA ANTIGEN CLASS 1; MEMBRANE PROTEIN;

ADULT; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; FEMALE; FERRITIN BLOOD LEVEL; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENOTYPE; HEMOCHROMATOSIS; HOMOZYGOTE; HUMAN; IRON BLOOD LEVEL; IRON METABOLISM; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; MENOPAUSE; MODIFIER GENE; PREGNANCY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TF GENE; TRANSFERRIN BLOOD LEVEL; AMINO ACID SUBSTITUTION; BIOLOGICAL MODEL; BLOOD; CLINICAL TRIAL; FRANCE; GENETICS; ITALY; METABOLISM; MIDDLE AGED; MULTICENTER STUDY;

ADULT; AMINO ACID SUBSTITUTION; FEMALE; FRANCE; GENES, MODIFIER; GENOME-WIDE ASSOCIATION STUDY; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HOMOZYGOTE; HUMANS; IRON; ITALY; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MODELS, BIOLOGICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSFERRIN;

EID: 84922962794     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.10.017     Document Type: Article

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