Telemedicine screening for cytomegalovirus retinitis at the point of care for human immunodeficiency virus infection

JAMA Ophthalmology

Volumn 133, Issue 2, 2015, Pages 198-205

  Jirawison, Choeng ^a   Yen, Michael ^b,c   Leenasirimakul, Prattana ^a   Chen, Jenny ^b,d,e   Guadanant, Siripim ^a   Kunavisarut, Paradee ^f   Patikulsila, Direk ^f   Watanachai, Nawat ^f   Ausayakhun, Somsanguan ^f   Heiden, David ^g   Holland, Gary N ^d   Margolis, Todd P ^b,h   Keenan, Jeremy D ^b  

^a NAKORNPING HOSPITAL   (Thailand)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d JULES STEIN EYE INSTITUTE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Faculty of Medicine Chiang Mai University   (Thailand)

^g CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^h WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CLINICAL FEATURE; CYTOMEGALOVIRUS RETINITIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; EYE PHOTOGRAPHY; FALSE NEGATIVE RESULT; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; OPHTHALMOLOGIST; OPHTHALMOSCOPY; POINT OF CARE TESTING; PREDICTIVE VALUE; PRIORITY JOURNAL; SCREENING TEST; SENSITIVITY AND SPECIFICITY; TELEDIAGNOSIS; THAILAND; VISUAL ACUITY; AIDS-RELATED OPPORTUNISTIC INFECTIONS; FOLLOW UP; HOSPITAL INFORMATION SYSTEM; INCIDENCE; MASS SCREENING; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; RETINA; RETROSPECTIVE STUDY; TELEMEDICINE;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; CYTOMEGALOVIRUS RETINITIS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MASS SCREENING; POINT-OF-CARE SYSTEMS; REPRODUCIBILITY OF RESULTS; RETINA; RETROSPECTIVE STUDIES; TELEMEDICINE; THAILAND; VISUAL ACUITY;

EID: 84922933715     PISSN: 21686165     EISSN: 21686173     Source Type: Journal    
DOI: 10.1001/jamaophthalmol.2014.4766     Document Type: Article

References (34)

1. Ford N, Shubber Z, Saranchuk P, et al. Burden of HIV-related cytomegalovirus retinitis in resource-limited settings: a systematic review. Clin Infect Dis. 2013;57(9):1351-1361.
2. Heiden D, Ford N, Wilson D, et al. Cytomegalovirus retinitis: the neglected disease of the AIDS pandemic. PLoS Med. 2007;4(12):e334.
3. Pathanapitoon K, Ausayakhun S, Kunavisarut P, et al. Blindness and low vision in a tertiary ophthalmologic center in Thailand: the importance of cytomegalovirus retinitis. Retina. 2007;27(5): 635-640.
4. Gharai S, Venkatesh P, Garg S, Sharma SK, Vohra R. Ophthalmic manifestations of HIV infections in India in the era of HAART: analysis of 100 consecutive patients evaluated at a tertiary eye care center in India. Ophthalmic Epidemiol. 2008;15 (4):264-271.
5. Nkomazana O, Tshitswana D. Ocular complications of HIV infection in sub-Sahara Africa. Curr HIV/AIDS Rep. 2008;5(3):120-125.
6. Thorne JE, Jabs DA, Kempen JH, Holbrook JT, Nichols C, Meinert CL; Studies of Ocular Complications of AIDS Research Group. Causes of visual acuity loss among patients with AIDS and cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Ophthalmology. 2006;113(8): 1441-1445.
7. Holland GN, Shuler JD. Progression rates of cytomegalovirus retinopathy in ganciclovir-treated and untreated patients. Arch Ophthalmol. 1992; 110(10):1435-1442.
8. Resnikoff S, Felch W, Gauthier TM, Spivey B. The number of ophthalmologists in practice and training worldwide: a growing gap despite more than 200 000 practitioners. Br J Ophthalmol. 2012;96 (6):783-787.
9. Estopinal CB, Ausayakhun S, Ausayakhun S, et al. Access to ophthalmologic care in Thailand: a regional analysis. Ophthalmic Epidemiol. 2013;20 (5):267-273.
10. Freeman EE, Roy-Gagnon MH, Samson E, et al. The global burden of visual difficulty in low, middle, and high income countries. PLoS One. 2013;8(5): e63315. doi:10.1371/journal.pone.0063315.
11. Sommer A. Global access to eye care. Arch Ophthalmol. 2007;125(3):399-400.
12. Ausayakhun S, Keenan JD, Ausayakhun S, et al. Clinical features of newly diagnosed cytomegalovirus retinitis in northern Thailand. Am J Ophthalmol. 2012;153(5):923-931.e1. doi:10.1016/j.ajo.2011.10.012.
13. Heiden D, Saranchuk P. CMV retinitis in China and SE Asia: the way forward [editorial]. BMC Infect Dis. 2011;11:327.
14. Shi Y, Lu H, He T, et al. Prevalence and clinical management of cytomegalovirus retinitis in AIDS patients in Shanghai, China. BMC Infect Dis. 2011;11: 326. doi:10.1186/1471-2334-11-326.
15. Ausayakhun S, Skalet AH, Jirawison C, et al. Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis. Am J Ophthalmol. 2011;152(6):1053-1058.e1. doi:10.1016/j.ajo.2011.05.030.
16. Shah JM, Leo SW, Pan JC, et al. Telemedicine screening for cytomegalovirus retinitis using digital fundus photography. Telemed J E Health. 2013;19 (8):627-631.
17. Yen M, Ausayakhun S, Chen J, et al. Telemedicine diagnosis of cytomegalovirus retinitis by nonophthalmologists. JAMA Ophthalmol. 2014; 132(9):1052-1058.
18. Holland GN, Buhles WC Jr, Mastre B, Kaplan HJ; UCLA CMV Retinopathy Study Group. A controlled retrospective study of ganciclovir treatment for cytomegalovirus retinopathy: use of a standardized system for the assessment of disease outcome. Arch Ophthalmol. 1989;107(12):1759-1766.
19. Holland GN, Vaudaux JD, Jeng SM, et al; UCLA CMV Retinitis Study Group. Characteristics of untreated AIDS-related cytomegalovirus retinitis, I: findings before the era of highly active antiretroviral therapy (1988 to 1994). Am J Ophthalmol. 2008; 145(1):5-11.
20. Ausayakhun S, Watananikorn S, Ittipunkul N, Chaidaroon W, Patikulsila P, Patikulsila D. Epidemiology of the ocular complications of HIV infection in Chiang Mai. J Med Assoc Thai. 2003;86 (5):399-406.
21. Saari JM, Summanen P, Kivelä T, Saari KM. Sensitivity and specificity of digital retinal images in grading diabetic retinopathy. Acta Ophthalmol Scand. 2004;82(2):126-130.
22. Liesenfeld B, Kohner E, Piehlmeier W, et al. A telemedical approach to the screening of diabetic retinopathy: digital fundus photography. Diabetes Care. 2000;23(3):345-348.
23. Tun N, London N, Kyaw MK, et al. CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar. J Int AIDS Soc. 2011;14:41.
24. Tangmonkongvoragul C, Ausayakhun S. Causes of visual acuity loss among HIV-infected patients with cytomegalovirus retinitis in the era of highly active antiretroviral therapy in Chiang Mai University Hospital. J Med Assoc Thai. 2012;95(suppl 4):S129-S135.
25. Jabs DA, Ahuja A, Van Natta M, Dunn JP, Yeh S; Studies of the Ocular Complications of AIDS Research Group. Comparison of treatment regimens for cytomegalovirus retinitis in patients with AIDS in the era of highly active antiretroviral therapy. Ophthalmology. 2013;120(6):1262-1270.
26. Freeman WR, Friedberg DN, Berry C, et al. Risk factors for development of rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis. Am J Ophthalmol. 1993;116(6):713-720.
27. Jabs DA, Enger C, Haller J, de Bustros S. Retinal detachments in patients with cytomegalovirus retinitis. Arch Ophthalmol. 1991;109(6):794-799.
28. Kempen JH, Jabs DA, Dunn JP, West SK, Tonascia J. Retinal detachment risk in cytomegalovirus retinitis related to the acquired immunodeficiency syndrome. Arch Ophthalmol. 2001;119(1):33-40.
29. Kempen JH, Martin BK, Wu AW, Barron B, Thorne JE, Jabs DA; Studies of Ocular Complications of AIDS Research Group. The effect of cytomegalovirus retinitis on the quality of life of patients with AIDS in the era of highly active antiretroviral therapy. Ophthalmology. 2003;110(5): 987-995.
30. Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial, 5: clinical features of cytomegalovirus retinitis at diagnosis: studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group. Am J Ophthalmol. 1997;124(2):141-157.
31. Holland GN, Vaudaux JD, Shiramizu KM, et al; Southern California HIV/Eye Consortium. Characteristics of untreated AIDS-related cytomegalovirus retinitis, II: findings in the era of highly active antiretroviral therapy (1997 to 2000). Am J Ophthalmol. 2008;145(1):12-22.
32. Jabs DA, Van Natta ML, Kempen JH, et al. Characteristics of patients with cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Am J Ophthalmol. 2002;133(1):48-61.
33. Yiengprugsawan V, Carmichael G, Lim LY, Seubsman S, Sleigh A. Explanation of inequality in utilization of ambulatory care before and after universal health insurance in Thailand. Health Policy Plan. 2011;26(2):105-114.
34. Himakalasa W, Grisurapong S, Phuangsaichai S. Access to antiretroviral therapy among HIV/AIDS patients in Chiang Mai province, Thailand. HIV AIDS (Auckl). 2013;5:205-213.