Sympathetic neural adaptations to exercise training in humans

Autonomic Neuroscience: Basic and Clinical

Volumn 188, Issue , 2015, Pages 36-43

  Carter, Jason R ^a   Ray, Chester A ^b  

^a MICHIGAN TECHNOLOGICAL UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Aerobic training; Heart failure; Microneurography; Resistance training; Sympathetic nerve activity

Indexed keywords

ADAPTATION; AEROBIC EXERCISE; ARTICLE; CARDIOVASCULAR RISK; EXERCISE; HEART FAILURE; HEART INFARCTION; HUMAN; METABOLIC SYNDROME X; MUSCLE SYMPATHETIC NERVE ACTIVITY; NEUROGRAPHY; OBESITY; PRIORITY JOURNAL; RESISTANCE TRAINING; SLEEP DISORDERED BREATHING; ADRENERGIC SYSTEM; CARDIOVASCULAR DISEASES; KINESIOTHERAPY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; CARDIOVASCULAR DISEASES; EXERCISE; EXERCISE THERAPY; HUMANS; SYMPATHETIC NERVOUS SYSTEM;

EID: 84922931708     PISSN: 15660702     EISSN: 18727484     Source Type: Journal    
DOI: 10.1016/j.autneu.2014.10.020     Document Type: Article

References (42)

1. Alvarez G.E., Beske S.D., Ballard T.P., Davy K.P. Sympathetic neural activation in visceral obesity. Circulation 2002, 106:2533-2536.
2. Alvarez G.E., Halliwill J.R., Ballard T.P., Beske S.D., Davy K.P. Sympathetic neural regulation in endurance-trained humans: fitness vs. fatness. J. Appl. Physiol. 2005, 98:498-502.
3. Antunes-Correa L.M., Melo R.C., Nobre T.S., Ueno L.M., Franco F.G.M., Braga A.M.W., Rondon M.U.P.B., Brum P.C., Barretto A.C.P., Middlekauff H.R., Negrao C.E. Impact of gender on benefits of exercise training on sympathetic nerve activity and muscle blood flow in heart failure. Eur. J. Heart Fail. 2010, 12:58-65.
4. Antunes-Correa L.M., Kanamura B.Y., Melo R.C., Nobre T.S., Ueno L.M., Franco F.G.M., Roveda F., Braga A.M., Rondon M.U.P.B., Brum P.C., Barretto A.C.P., Middlekauff H.R., Negrao C.E. Exercise training improves neurovascular control and functional capacity in heart failure patients regardless of age. Eur. J. Prev. Cardiol. 2012, 19:822-829.
5. Carter J.R., Ray C.A., Downs E.M., Cooke W.H. Strength training reduces arterial blood pressure but not sympathetic neural activity in young normotensive subjects. J. Appl. Physiol. 2003, 94:2212-2216.
6. Cohn J.N., Levine T.B., Olivari M.T., Garberg V., Lura D., Francis G.S., Simon A.B., Rector T. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart-failure. N. Engl. J. Med. 1984, 311:819-823.
7. Cooke W.H., Reynolds B.V., Yandl M.G., Carter J.R., Tahvanainen K.U.O., Kuusela T.A. Effects of exercise training on cardiovagal and sympathetic responses to Valsalva's maneuver. Med. Sci. Sports Exerc. 2002, 34:928-935.
8. Esler M., Lambert G., Brunner-La Rocca H.P., Vaddadi G., Kaye D. Sympathetic nerve activity and neurotransmitter release in humans: translation from pathophysiology into clinical practice. Acta Physiol. Scand. 2003, 177:275-284.
9. Fraga R., Franco F.G., Roveda F., de Matos L.N.J., Braga A.M.F.W., Rondon M.U.P.B., Rotta D.R., Brum P.C., Barretto A.C.P., Middlekauff H.R., Negrao C.E. Exercise training reduces sympathetic nerve activity in heart failure patients treated with carvedilol. Eur. J. Heart Fail. 2007, 9:630-636.
10. Franco F.G.D., Santos A.C., Rondon M.U.P., Trombetta I.C., Strunz C., Braga A.M.W., Middlekauff H., Negrao C.E., Barretto A.C.P. Effects of home-based exercise training on neurovascular control in patients with heart failure. Eur. J. Heart Fail. 2006, 8:851-855.
11. Grassi G., Seravalle G., Calhoun D.A., Mancia G. Physical-training and baroreceptor control of sympathetic-nerve activity in humans. Hypertension 1994, 23:294-301.
12. Joyner M.J., Green D.J. Exercise protects the cardiovascular system: effects beyond traditional risk factors. J. Physiol. (Lond.) 2009, 587:5551-5558.
13. Laterza M.C., de Matos L.D.N.J., Trombetta I.C., Braga A.M.W., Roveda F., Alves M.J.N.N., Krieger E.M., Negrao C.E., Rondon M.U.P.B. Exercise training restores baroreflex sensitivity in never-treated hypertensive patients. Hypertension 2007, 49:1298-1306.
14. Macefield V.G., Wallin B.G., Vallbo A.B. The discharge behaviour of single vasoconstrictor motoneurones in human muscle nerves. J. Physiol. 1994, 481(Pt 3):799-809.
15. Martinez D.G., Nicolau J.C., Lage R.L., Toschi-Dias E., de Matos L.D.N.J., Alves M.J.N.N., Trombetta I.C., da Silva V.J.D., Middlekauff H.R., Negrao C.E., Rondon M.U.P.B. Effects of long-term exercise training on autonomic control in myocardial infarction patients. Hypertension 2011, 58:1049-U1152.
16. Mello P.R., Guerra G.M., Borile S., Rondon M.U., Alves M.J., Negrao C.E., Dal Lago P., Mostarda C., Irigoyen M.C., Consolim-Colombo F.M. Inspiratory muscle training reduces sympathetic nervous activity and improves inspiratory muscle weakness and quality of life in patients with chronic heart failure. A clinical trial. J. Cardpulm. Rehabil. 2012, 32:255-261.
17. Mimura J., Yuasa F., Yuyama R., Kawamura A., Iwasaki M., Sugiura T., Iwasaka T. The effect of residential exercise training on baroreflex control of heart rate and sympathetic nerve activity in patients with acute myocardial infarction. Chest 2005, 127:1108-1115.
18. Mueller P.J. Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Clin. Exp. Pharmacol. Physiol. 2007, 34:377-384.
19. Oneda B., Cardoso C.G., Forjaz C.L.M., Araujo T.G., Bernadardo F.R., Lima de Gusmao J., Pinto L.G., Labes E., Abrahao S.B., Mion D., Fonseca A.M., Tinucci T. Effects of estrogen therapy and aerobic training on sympathetic activity and hemodynamics in healthy postmenopausal women: a double-blind randomized trial. Menopause 2014, 21:369-375.
20. Pescatello L.S., Franklin B.A., Fagard R., Farquhar W.B., Kelley G.A., Ray C.A., American College of Sports Medicine Exercise and hypertension. Med. Sci. Sports Exerc. 2004, 36:533-553.
21. Ray C.A. Sympathetic adaptations to one-legged training. J. Appl. Physiol. 1999, 86:1583-1587.
22. Ray C.A., Carrasco D.I. Isometric handgrip training reduces arterial pressure at rest without changes in sympathetic nerve activity. Am. J. Physiol. Heart Circ. Physiol. 2000, 279:H245-H249.
23. Ray C.A., Carter J.R. Effects of aerobic exercise training on sympathetic and renal responses to mental stress in humans. Am. J. Physiol. Heart Circ. Physiol. 2010, 298:H229-H234.
24. Ray C.A., Hume K.M. Sympathetic neural adaptations to exercise training in humans: insights from microneurography. Med. Sci. Sports Exerc. 1998, 30:387-391.
25. Roveda F., Middlekauff H.R., Rondon M.U.P.B., Reis S.F., Souza M., Nastari L., Barretto A.C.P., Krieger E.M., Negrao C.E. The effects of exercise training on sympathetic neural activation in advanced heart failure - a randomized controlled trial. J. Am. Coll. Cardiol. 2003, 42:854-860.
26. Rowell L.B. Human Cardiovascular Control 1993, Oxford University Press, New York.
27. Rozanski A., Blumenthal J.A., Kaplan J. Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation 1999, 99:2192-2217.
28. Saito M., Iwase S., Hachiya T. Resistance exercise training enhances sympathetic nerve activity during fatigue-inducing isometric handgrip trials. Eur. J. Appl. Physiol. 2009, 105:225-234.
29. Sheldahl L.M., Ebert T.J., Cox B., Tristani F.E. Effect of aerobic training on baroreflex regulation of cardiac and sympathetic function. J. Appl. Physiol. 1994, 76:158-165.
30. Sinoway L., Shenberger J., Leaman G., Zelis R., Gray K., Baily R., Leuenberger U. Forearm training attenuates sympathetic responses to prolonged rhythmic forearm exercise. J. Appl. Physiol. 1996, 81:1778-1784.
31. Somers V.K., Leo K.C., Shields R., Clary M., Mark A.L. Forearm endurance training attenuates sympathetic-nerve response to isometric handgrip in normal humans. J. Appl. Physiol. 1992, 72:1039-1043.
32. Straznicky N.E., Lambert E.A., Nestel P.J., McGrane M.T., Dawood T., Schlaich M.P., Masuo K., Eikelis N., de Courten B., Mariani J.A., Esler M.D., Socratous F., Chopra R., Sari C.I., Paul E., Lambert G.W. Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects. Diabetes 2010, 59:71-79.
33. Straznicky N.E., Grima M.T., Eikelis N., Nestel P.J., Dawood T., Schlaich M.P., Chopra R., Masuo K., Esler M.D., Sari C.I., Lambert G.W., Lambert E.A. The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components. J. Clin. Endocrinol. Metab. 2011, 96:E503-E508.
34. Svedenhag J., Wallin B.G., Sundlof G., Henriksson J. Skeletal-muscle sympathetic activity at rest in trained and untrained subjects. Acta Physiol. Scand. 1984, 120:499-504.
35. Tipton C.M. Exercise, training and hypertension: an update. Exerc. Sport Sci. Rev. 1991, 19:447-505.
36. Tonacio A.C., Trombetta I.C., Rondon M.U.P.B., Batalha L.T., Kuniyoshi F.H.S., Laterza M.C., Suzuki P.H., Gowdak M.M.G., Barretto A.C.P., Halpern A., Villares S.M.F., Negrao C.E. Effects of diet and exercise training on neurovascular control during mental stress in obese women. Braz. J. Med. Biol. Res. 2006, 39:53-62.
37. Trombetta I.C., Batalha L.T., Rondon M.U.P.B., Laterza M.C., Kuniyoshi F.H.S., Gowdak M.M.G., Barretto A.C.P., Halpern A., Villares S.M.F., Negrao C.E. Weight loss improves neurovascular and muscle metaboreflex control in obesity. Am. J. Physiol. Heart Circ. Physiol. 2003, 285:H974-H982.
38. Ueno L.M., Drager L.F., Rodrigues A.C.T., Rondon M.U.P.B., Braga A.M.F.W., Mathias W., Krieger E.M., Barretto A.C.P., Middlekauff H.R., Lorenzi G., Negrao C.E. Effects of exercise training in patients with chronic heart failure and sleep apnea. Sleep 2009, 32:637-647.
39. Vallbo A.B., Hagbarth K.E., Wallin B.G. Microneurography: how the technique developed and its role in the investigation of the sympathetic nervous system. J. Appl. Physiol. 2004, 96:1262-1269.
40. Wallin B.G., Esler M., Dorward P., Eisenhofer G., Ferrier C., Westerman R., Jennings G. Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans. J. Physiol. 1992, 453:45-58.
41. Wallin B.G., Thompson J.M., Jennings G.L., Esler M.D. Renal noradrenaline spillover correlates with muscle sympathetic activity in humans. J. Physiol. 1996, 491(Pt 3):881-887.
42. Zucker I.H., Patel K.P., Schultz H.D., Li Y.F., Wang W., Pliquett R.U. Exercise training and sympathetic regulation in experimental heart failure. Exerc. Sport Sci. Rev. 2004, 32:107-111.