Propofol pretreatment attenuates lipopolysaccharide-induced acute lung injury in rats by activating the phosphoinositide-3-kinase/Akt pathway

Brazilian Journal of Medical and Biological Research

Volumn 47, Issue 12, 2014, Pages 1062-1067

  Zhao, L L ^a   Hu, G C ^b   Zhu, S S ^a   Li, J F ^c   Liu, G J ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF ILLINOIS   (United States)

^c Tengzhou Central People s Hospital   (China)

Author keywords

Acute lung injury; Lipopolysaccharide; PI3K Akt pathway; Propofol

Indexed keywords

INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PROPOFOL; TUMOR NECROSIS FACTOR ALPHA; WORTMANNIN; BICINCHONINIC ACID; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; QUINOLINE DERIVATIVE;

ACUTE LUNG INJURY; ADULT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGGREGATION; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; IMMUNE RESPONSE; LUNG CONGESTION; LUNG HEMORRHAGE; LUNG INFILTRATE; LUNG LAVAGE; LUNG WEIGHT; MALE; MORTALITY; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SURVIVAL; WESTERN BLOTTING; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; KAPLAN MEIER METHOD; LUNG; METABOLISM; SPRAGUE DAWLEY RAT;

RATTUS;

ACUTE LUNG INJURY; ANIMALS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; ENZYME-LINKED IMMUNOSORBENT ASSAY; INDICATORS AND REAGENTS; INTERLEUKIN-6; KAPLAN-MEIER ESTIMATE; LIPOPOLYSACCHARIDES; LUNG; MALE; PHOSPHATIDYLINOSITOL 3-KINASES; PROPOFOL; PROTO-ONCOGENE PROTEINS C-AKT; QUINOLINES; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84922888424     PISSN: None     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/1414-431X20143949     Document Type: Article

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