LRP5 regulates human body fat distribution by modulating adipose progenitor biology in a dose- and depot-specific fashion

Cell Metabolism

Volumn 21, Issue 2, 2015, Pages 262-273

  Loh, Nellie Y ^a   Neville, Matt J ^a,b   Marinou, Kyriakoula ^a,c   Hardcastle, Sarah A ^d   Fielding, Barbara A ^a,e   Duncan, Emma L ^f,g   McCarthy, Mark I ^a,b   Tobias, Jonathan H ^d   Gregson, Celia L ^d   Karpe, Fredrik ^a,b   Christodoulides, Constantinos ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e UNIVERSITY OF SURREY   (United Kingdom)

^f UNIVERSITY OF QUEENSLAND   (Australia)

^g ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; INSULIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ICTR14 COMPOUND; LRP5 PROTEIN, HUMAN;

ABDOMINAL OBESITY; ADIPOCYTE; ADIPOGENESIS; ADIPOSE DERIVED STEM CELL; ADULT; ANTHROPOMETRY; ARTICLE; BODY FAT; BODY FAT DISTRIBUTION; BONE MASS; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INTRAABDOMINAL FAT; LIPID STORAGE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; WNT SIGNALING PATHWAY; ADIPOSE TISSUE; ALLELE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; MIDDLE AGED; MUTATION; STEM CELL; TRANSCRIPTION INITIATION;

ADIPOGENESIS; ADIPOSE TISSUE; ADULT; ALLELES; BETA CATENIN; BODY FAT DISTRIBUTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEALTHY VOLUNTEERS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-5; MALE; MIDDLE AGED; MUTATION; STEM CELLS; THIAZOLIDINEDIONES; TRANSCRIPTIONAL ACTIVATION;

EID: 84922850897     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.01.009     Document Type: Article

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