Novel APP K724M mutation causes Chinese early-onset familial Alzheimer's disease and increases amyloid-β42 to amyloid-β40 ratio

Neurobiology of Aging

Volumn 35, Issue 11, 2014, Pages 2657.e1-2657.e6

  Peng, Xiang Lei ^a   Hou, Lei ^a   Xu, Shao Hua ^a   Hua, Ying ^a   Zhou, Shu Jie ^b   Zhang, Ying ^a   Zheng, Yan Peng ^a   Fu, Yuan Hui ^a   Xu, Qing ^a   Zhang, Li Shu ^a   Wang, Jun ^a   Guan, Xiao Ting ^b   He, Jin Sheng ^a  

^a BEIJING JIAOTONG UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Amyloid precursor protein; Amyloid beta; Early onset familial Alzheimer's disease; K724M; Mutation

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; PEPTIDE FRAGMENT;

ADULT; ALZHEIMER DISEASE; APP GENE; APP695 GENE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CHINESE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; HEK293 CELL LINE; HUMAN; MALE; MUTATIONAL ANALYSIS; ONSET AGE; PEDIGREE ANALYSIS; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; GENETICS; METABOLISM; MIDDLE AGED; MUTATION; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC ASSOCIATION STUDIES; HEK293 CELLS; HUMANS; MALE; MIDDLE AGED; MUTATION; PEPTIDE FRAGMENTS;

EID: 84922845253     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.06.005     Document Type: Article

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