Development of potent inhibitors of pyocyanin production in pseudomonas aeruginosa

Journal of Medicinal Chemistry

Volumn 58, Issue 3, 2015, Pages 1298-1306

  Miller, Laura C ^a,c   O'Loughlin, Colleen T ^a,d   Zhang, Zinan ^a,e   Siryaporn, Albert ^a   Silpe, Justin E ^a   Bassler, Bonnie L ^a,b   Semmelhack, Martin F ^a  

^a PRINCETON UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c SAN JOSE STATE UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPYRIDINE; AMINOPYRIDINE DERIVATIVE; LACTONE DERIVATIVE; PYOCYANINE; PYRAZINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; VIRULENCE FACTOR; AMIDE; ANTIINFECTIVE AGENT; MOLECULAR LIBRARY;

ARTICLE; BACTERIAL VIRULENCE; CELL DENSITY; CONTROLLED STUDY; DOWN REGULATION; HYDROGEN BOND; MOLECULAR LIBRARY; MOLECULE; NONHUMAN; OXIDATIVE STRESS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; QUORUM SENSING; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MICROBIAL SENSITIVITY TEST; PHARMACOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMIDES; ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PSEUDOMONAS AERUGINOSA; PYOCYANINE; PYRIDINES; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84922761855     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm5015082     Document Type: Article

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