Genetic variants modify the effect of age on APOE methylation in the genetics of lipid lowering drugs and diet network study

Aging Cell

Volumn 14, Issue 1, 2015, Pages 49-59

  Ma, Yiyi ^a   Smith, Caren E ^a   Lai, Chao Qiang ^a   Irvin, Marguerite R ^b   Parnell, Laurence D ^a   Lee, Yu Chi ^a   Pham, Lucia ^a   Aslibekyan, Stella ^b   Claas, Steven A ^b   Tsai, Michael Y ^c   Borecki, Ingrid B ^d   Kabagambe, Edmond K ^e   Berciano, Silvia ^f   Ordovás, José M ^a,f,g   Absher, Devin M ^h   Arnett, Donna K ^b  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^f IMDEA FOOD INSTITUTE   (Spain)

^g CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^h HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

Author keywords

Age; Apolipoprotein E; DNA methylation; Epidemiology; Interaction; Variants

Indexed keywords

APOLIPOPROTEIN E; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTILIPEMIC AGENT; LIPID;

ADULT; AGE; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CPG ISLAND; DNA METHYLATION; EXON; FEMALE; GENE EXPRESSION; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC VARIABILITY; HUMAN; INTRON; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; PROMOTER REGION; ADOLESCENT; AGING; BLOOD; DIET; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC VARIATION; GENETICS; LYMPHOCYTE; METABOLISM; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; APOLIPOPROTEINS E; DIET; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; GENETIC VARIATION; HUMANS; HYPOLIPIDEMIC AGENTS; LIPIDS; LYMPHOCYTES; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84922722937     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12293     Document Type: Article

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