Brain pericyte-derived soluble factors enhance insulin sensitivity in GT1-7 hypothalamic neurons

Biochemical and Biophysical Research Communications

Volumn 457, Issue 4, 2015, Pages 532-537

  Takahashi, Hiroyuki ^a   Takata, Fuyuko ^a,b   Matsumoto, Junichi ^a   Machida, Takashi ^a   Yamauchi, Atsushi ^a   Dohgu, Shinya ^a   Kataoka, Yasufumi ^a,b  

^a FUKUOKA UNIVERSITY   (Japan)

^b PharmaCo Cell Co Ltd   (Japan)

Author keywords

Hypothalamus; Insulin receptor; Insulin signaling; Neuron; Neurovascular unit; Pericyte

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; LAMININ; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B; UNCLASSIFIED DRUG; CULTURE MEDIUM;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN PERICYTE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME PHOSPHORYLATION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INSULIN SENSITIVITY; MALE; MICROVASCULATURE; MOUSE; NERVE CELL; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL LINE; CULTURE MEDIUM; CYTOLOGY; INSULIN RESISTANCE; METABOLISM; PERICYTE; RAT; VASCULARIZATION; WISTAR RAT;

MURINAE; RATTUS;

ANIMALS; CELL LINE; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; HYPOTHALAMUS; INSULIN; INSULIN RESISTANCE; MICE; PERICYTES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTOR, INSULIN; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION;

EID: 84922710799     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.01.016     Document Type: Article

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