Biodegradation of the Antituberculosis Drug Isoniazid in the Aquatic Environment

Clean - Soil, Air, Water

Volumn 43, Issue 2, 2015, Pages 166-172

  Sasu, Samuel ^a,b   Metzger, Jörg ^b   Kranert, Martin ^b   Kümmerer, Klaus ^a  

^a LEUPHANA UNIVERSITY OF LÜNEBURG   (Germany)

^b UNIVERSITY OF STUTTGART   (Germany)

Author keywords

Biodegradation of the antituberculosis drug isoniazid in the aquatic environment; Biological degradation; Pharmaceuticals; Sewage treatment plant; Surface water

Indexed keywords

AQUATIC ENVIRONMENT; BIODEGRADATION; DRUG; SEWAGE TREATMENT; SURFACE WATER; WASTE MANAGEMENT;

GHANA;

BACTERIA (MICROORGANISMS);

EID: 84922696405     PISSN: 18630650     EISSN: 18630669     Source Type: Journal    
DOI: 10.1002/clen.201100147     Document Type: Article

References (38)

1. J.H. Al-Rifai, C.L. Gabelish, A.I. Schäfer, Occurrence of Pharmaceutically Active and Non-steroidal Estrogenic Compounds in Three Different Wastewater Recycling Schemes in Australia Chemosphere 69 2007; 803-815
2. A. Boxall, R. Breton, Pharmaceuticals and Personal Care Products in the Environment: Regulatory Drivers and Research Needs, QSAR Comb Sci. 223 2003; 399-409
3. M.L. Richardson, J.M. Bowron, The fate of pharmaceutical chemicals in the aquatic environment J. Pharm. Pharmacol. 37 1985; 1-12
4. H.J. Stan, T. Heberer, M. Linkerhägner, Vorkommen von Clofibrinsäure im Gewaessersystem - Ist der humanmedizinische Gebrauch Ursache fär die Kontamination von Oberflächen-, Grund- und Trinkwasser Vom Wasser 83 1994; 57-68
5. K. Kümmerer, T. Steger-Hartmann, M. Meyer, Biodegradability of the Anti-tumor Agent Ifosfamide and Its Occurrence in Hospital Effluents and Sewage Water Res. 31 1997; 2705-2710
6. K. Kümmerer, E. Helmers, Hospital effluents as a source for platinum in the environment Sci. Total Environ. 193 1997; 179-184
7. M. Stumpf, T.A. Ternes, K. Haberer, P. Seel, Determination of Pharmaceuticals in Sewage Plants and River Water Vom Wasser 86 1996; 291-303
8. R. Hirsch, T. Ternes, K. Haberer, K.L. Kratz, Occurrence of antibiotics in the aquatic environment Sci. Total Environ. 225 1999; 109-118
9. K. Kümmerer, Pharmaceuticals the Environment: Sources, Fate, Eeffects, Risks, 2nd Edn., Springer Heidelberg, Germany 2004;
10. T. Ternes, Occurrence of drugs in German sewage treatment plants and rivers Water Res. 32 1998; 3245-3260
11. R.A. Trenholm, B.J. Vanderford, J.C. Holady, D.J. Rexing, S.A. Snyder, Broad range analysis of endocrine disruptors and pharmaceuticals using gas chromatography and liquid chromatography tandem mass spectrometry Chemosphere 65 2006; 1990-1998
12. WHO, TB-A Global Emergency, Report on the TB Epidemic World Health Organization Geneva, Switzerland 1994
13. WHO, Global Tuberculosis Control: Epidemiology, Strategy, Financing, World Health Organization Geneva, Switzerland 2009
14. W.F.J. Cuthbertson, D.M. Ireland, W. Wolff, Detection and identification of some metabolites of isonicotinic acid hydrazide (isoniazid) in human urine Biochem. J. 55 1953; 669-671
15. I.M. Westwood, S.J. Holton, F. Rodrigues-Lima, J.M. Dupret, S. Bhakta, M.E. Noble, E. Sim, Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase Biochem. J. 385 2005; 605-612
16. G.A. Ellard, P.T. Gammon, S.M. Wallace, The determination of isoniazid and its metabolites acetylisoniazid, monoacetylhydrazine, diacetylhydrazine, isonicotinic acid and isonicotinylglycine in serum and urine Biochem. J. 126 1972; 449-458
17. G.D. Rose, Community-Based Technologies for Domestic Wastewater Treatment and Reuse: Options for urban agriculture Cities Feeding People Series, Report 27, International Development Research Centre Ottawa, Canada 1999;
18. A.N. Bdour, M.R. Hamdi, Z. Tarawneh, Perspectives on Sustainable Wastewater Treatment Technologies and Reuse Options in the Urban Areas of the Mediterranean Region Desalination 237 2009; 162-174
19. N.F. Poole, A.E. Meyer, Stability of Isoniazid in Aqueous Solutions and Plasma Proc. Soc. Exp. Biol. Med. 104 1960; 560-562
20. A. Hutchings, B.P. Spragg, P.A. Routledge, Stability of Isoniazid and Acetylisoniazid in Aaliva Ther. Drug Monit. 102 1988; 234-236
21. J.H. Peters, Studies on the Metabolism of Isoniazid. Development and Application of a Fluorometric Procedure for Measuring Isoniazid in Blood Am. Rev. Respir. Dis. 81 1960; 485-497
22. H.C. Chiang, L.J. Lin, Photolysis of Isoniazid J. Chin. Chem. Soc. 253 1978; 125-130
23. OECD, Introduction to the OECD Guidelines for Testing of Chemicals, Section 3, Part 1: Principles and Strategies Related to the Testing of Degradation of Organic Chemicals, Organization of Economic Cooperation and Development Paris, France 1993;
24. N. Nyholm, The European System of Standardized Legal Lests for Assessing the Biodegradability of Chemicals Environ. Toxicol. Chem. 10 1991; 1237-1246
25. OECD, Guidelines for Testing of Chemicals: Ready Biodegradability, Organization of Economic Cooperation and Development Paris, France 1992;
26. American Chemistry Council, Biodegradability and Organic Compounds, ACC Washington DC, USA 2007;
27. C. Trautwein, K. Kümmerer, J.W. Metzger, Aerobic Biodegradability of the Calcium Channel Antagonist Verapamil and Identification of a Microbial Dead-end Transformation Product Studied by LC-MS/MS Chemosphere 72 2008; 442-450
28. A. Haiss, K. Kümmerer, Biodegradability of the X-ray Contrast Compound Diatrizoic Acid, Identification of Aerobic Degradation Products and Effects Against Sewage Sludge Micro-organisms Chemosphere 62 2006; 294-302
29. OECD, Guidelines for Testing of Chemicals 301 D Closed Bottle Test, 302 B Zahn-Wellens Test, Adopted by the Council on 17th July, Organization of Economic Cooperation and Development Paris, France 1992;
30. K. Kümmerer, A. Al-Ahmad, T. Steger-Hartmann, Epirubicin hydrochloride in the aquatic environment-biodegradation and bacterial toxicity, Umweltmed. Forsch. Prax. 1 1996; 133-137
31. ISO, Water quality-determination of dissolved oxygen, in ISO 5414, German Standard Methods for the Examination of Water, Wastewater and Sludge Beuth Verlag Berlin 1990;
32. L.P. O'Malley, Evaluation and Modification of the OECD 301F Respirometry Biodegradation Test Method with Regard to Test Substance Concentration and Inoculum Water Air Soil Pollut. 177 2006; 251-265
33. OECD, Guidelines for Testing of Chemicals 302 B, Zahn-Wellens Test, Organization of Economic Cooperation and Development Paris, France 1992;
34. DIN 38 414, German standard methods for the examination of water, waste water and sludge; sludge and sediments (group S); determination of the moisture content and the dry residue respectively the dry solid substance (S2), Deutsches Institut für Normung Berlin 1985;
35. DIN EN 1484, Water analysis-Guidelines for the determination of total organic carbon (TOC) and dissolved organic carbon (DOC) Beuth Verlag Berlin 1997;
36. J. Blok, A. de Moriser, P. Gerike, L. Reynolds, H. Wellens, Harmonization of Ready Biodegradability Tests Chemosphere 14 1985; 1805-1820
37. B.A. Wiggins, M. Alexander, Role of Chemical Concentration and Second Sources in Acclimation of Microbial Communities for Biodegradation Appl. Environ. Microbiol. 54 1988; 2803-2807
38. H.M. Watson, A Comparison of the Effects of Two Methods of Acclimation on Aerobic Biodegradability Environ. Toxicol. Chem. 12 1993; 2023-2030