Evolution of osmotic pressure in solid tumors

Journal of Biomechanics

Volumn 47, Issue 14, 2014, Pages 3441-3447

  Voutouri, Chysovalantis ^a   Stylianopoulos, Triantafyllos ^a  

^a UNIVERSITY OF CYPRUS   (Cyprus)

Author keywords

Donnan osmotic pressure; Fixed charged density; Glycosaminoglycans; Tumor mechanics; Tumor microenvironment

Indexed keywords

MATHEMATICAL MODELS; STRESSES; TRANSPORT PROPERTIES; TUMORS;

BIO-MECHANICAL MODELS; CANCER PROGRESSION; CHARGED DENSITY; GLYCOSAMINOGLYCANS; INTERSTITIAL FLUID PRESSURES; INTERSTITIAL SPACE; MICROENVIRONMENTS; TUMOR MICROENVIRONMENT;

OSMOSIS;

GLYCOSAMINOGLYCAN;

ADENOCARCINOMA; ANION TRANSPORT; ARTICLE; BIOMECHANICS; CANCER GROWTH; CARBOHYDRATE ANALYSIS; CARCINOGENESIS; CATION TRANSPORT; CONTROLLED STUDY; HYDRAULIC CONDUCTIVITY; INTERSTITIUM; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MELANOMA; OSMOTIC PRESSURE; PHASE TRANSITION; PREDICTIVE VALUE; SARCOMA; SOLID TUMOR; SPATIAL ANALYSIS; TISSUE PRESSURE; TUMOR MICROENVIRONMENT; TUMOR MODEL; BIOLOGICAL MODEL; DISEASE COURSE; EXTRACELLULAR FLUID; HUMAN; METABOLISM; NEOPLASM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADENOCARCINOMA; BIOMECHANICAL PHENOMENA; DISEASE PROGRESSION; EXTRACELLULAR FLUID; GLYCOSAMINOGLYCANS; HUMANS; MELANOMA; MODELS, BIOLOGICAL; NEOPLASMS; OSMOTIC PRESSURE; SARCOMA; TUMOR MICROENVIRONMENT;

EID: 84922687928     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2014.09.019     Document Type: Article

References (35)

1. Ambrosi D., Mollica F. On the mechanics of a growing tumor. Int. J. Eng. Sci. 2002, 40:1297-1316.
2. Baxter L.T., Jain R.K. Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection. Microvasc. Res. 1989, 37:77-104.
3. Boucher Y., Jain R.K. Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. Cancer Res. 1992, 52:5110-5114.
4. Casciari J.J., Sotirchos S.V., Sutherland R.M. Mathematical modelling of microenvironment and growth in EMT6/Ro multicellular tumour spheroids. Cell Prolif. 1992, 25:1-22.
5. Casciari J.J., Sotirchos S.V., Sutherland R.M. Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH. J. Cell. Physiol. 1992, 151:386-394.
6. Chauhan V.P., Martin J.D., Liu H., Lacorre D.A., Jain S.R., Kozin S.V., Stylianopoulos T., Mousa A., Han X., Adstamongkonkul P., Popovic Z., Bawendi M.G., Boucher Y., Jain R.K. Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumor blood vessels. Nat. Commun. 2013, 4:2516. 10.1038/ncomms.3516.
7. Cheng G., Tse J., Jain R.K., Munn L.L. Micro-environmental mechanical stress controls tumor spheroid size and morphology by suppressing proliferation and inducing apoptosis in cancer cells. PLoS One 2009, 4:e4632.
8. Helmlinger G., Netti P.A., Lichtenbeld H.C., Melder R.J., Jain R.K. Solid stress inhibits the growth of multicellular tumor spheroids. Nat. Biotechnol. 1997, 15:778-783.
9. Jackson A.R., Yuan T.Y., Huang C.Y., Gu W.Y. A conductivity approach to measuring fixed charge density in intervertebral disc tissue. Ann. Biomed. Eng. 2009, 37:2566-2573.
10. Jain R.K., Martin J.D., Stylianopoulos T. The role of mechanical forces in tumor progression and therapy. Ann. Rev. Biomed. Eng. 2014, 16:321-346.
11. Jain R.K., Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat. Rev. Clin. Oncol. 2010, 7:653-664.
12. Jim M., Grodzinsky A.J. Effect of electrostatic interactions between glycosaminoglycans on the shear stiffness of cartilage: a molecular model and experiments. Macromolecules 2001, 34:8330-8339.
13. Kim Y., Stolarska M.A., Othmer H.G. The role of the micro environment in tumor growth and invasion. Progress in Biophysics and Molecular Biology 2011, 106:353-379.
14. Koumoutsakos P., Pivkin I., Milde F. The fluid mechanics of cancer and its therapy. Ann. Rev. Fluid Mech. 2013, 45:325-355.
15. Lesperance L.M., Gray M.L., Burstein D. Determination of fixed charge density in cartilage using nuclear magnetic resonance. J. Orthop. Res.: Off. Publ. Orthop. Res. Soc. 1992, 10:1-13.
16. Levick J.R. Flow through interstitium and other fibrous matrices. Q J. Exp. Physiol. 1987, 72:409-437.
17. Lu X.L., Wan L.Q., Guo X.E., Mow V.C. A linearized formulation of triphasic mixture theory for articular cartilage, and its application to indentation analysis. J. Biomechan. 2010, 43:673-679.
18. MacLaurin J., Chapman J., Jones G.W., Roose T. The buckling of capillaries in solid tumours. Proc. R. Soc. A 2012, 468:4123-4145.
19. Mattern K.J., Nakornchai C., Deen W.M. Darcy permeability of agarose-glycosaminoglycan gels analyzed using fiber-mixture and donnan models. Biophys. J. 2008, 95:648-656.
20. Mueller-Klieser W.F., Sutherland R.M. Oxygen consumption and oxygen diffusion properties of multicellular spheroids from two different cell lines. Advances in Experimental Medicine and Biology 1984, 180:311-321.
21. Netti P.A., Baxter L.T., Boucher Y., Skalak R., Jain R.K. Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery. Cancer Res. 1995, 55:5451-5458.
22. Netti P.A., Berk D.A., Swartz M.A., Grodzinsky A.J., Jain R.K. Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res. 2000, 60:2497-2503.
23. Padera T.P., Stoll B.R., Tooredman J.B., Capen D., di Tomaso E., Jain R.K. Pathology: cancer cells compress intratumour vessels. Nature 2004, 427:695.
24. Provenzano P.P., Cuevas C., Chang A.E., Goel V.K., Von Hoff D.D., Hingorani S.R. Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma. Cancer Cell 2012, 21:418-429.
25. Provenzano P.P., Hingorani S.R. Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer. Br. J. Cancer 2013, 108:1-8.
26. Rodriguez E.K., Hoger A., McCulloch A.D. Stress-dependent finite growth in soft elastic tissues. J. Biomech. 1994, 27:455-467.
27. Roose T., Netti P.A., Munn L.L., Boucher Y., Jain R.K. Solid stress generated by spheroid growth estimated using a linear poroelasticity model. Microvasc. Res. 2003, 66:204-212.
28. Skalak R., Zargaryan S., Jain R.K., Netti P.A., Hoger A. Compatibility and the genesis of residual stress by volumetric growth. J. Math. Biol. 1996, 34:889-914.
29. Stylianopoulos T., Jain R.K. Combining two strategies to improve perfusion and drug delivery in solid tumors. Proc. Natl. Acad. Sci. USA 2013, 110:18632-18637.
30. Stylianopoulos T., Martin J.D., Chauhan V.P., Jain S.R., Diop-Frimpong B., Bardeesy N., Smith B.L., Ferrone C.R., Hornicek F.J., Boucher Y., Munn L.L., Jain R.K. Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors. Proc. Natl. Acad. Sci. USA 2012, 109:15101-15108.
31. Stylianopoulos T., Martin J.D., Snuderl M., Mpekris F., Jain S.R., Jain R.K. Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse. Cancer Res. 2013, 73:3833-3841.
32. Sun D.N., Gu W.Y., Guo X.E., Lai W.M., Mow V.C. A mixed finite element formation fo triphasic mechano-electrochemocal thepry for charged, hydrated biological soft tissues. Int. J. Numer. Methods Eng. 1999, 45:1375-1402.
33. Taber L.A. Theoretical study of Beloussov[U+05F3]s hyper-restoration hypothesis for mechanical regulation of morphogenesis. Biomech. Model Mechanobiol. 2008, 7:427-441.
34. Tse J.M., Cheng G., Tyrrell J.A., Wilcox-Adelman S.A., Boucher Y., Jain R.K., Munn L.L. Mechanical compression drives cancer cells toward invasive phenotype. Proc. Natl. Acad. Sci. USA 2012, 109:911-916.
35. Wiig H., Swartz M.A. Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. Physiol. Rev. 2012, 92:1005-1060.