메뉴 건너뛰기




Volumn 10, Issue 12, 2014, Pages 1981-1992

Risk of cardiovascular toxicities in patients with solid tumors treated with sorafenib: An updated systematic review and meta-analysis

Author keywords

bleeding; cardiovascular toxicities; hypertension; left ventricular dysfunction; meta analysis; myocardial ischemia; sorafenib

Indexed keywords

SORAFENIB; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; NICOTINAMIDE;

EID: 84922681694     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.14.42     Document Type: Review
Times cited : (30)

References (37)
  • 1
    • 84893652695 scopus 로고    scopus 로고
    • Sorafenib does not improve efficacy of chemotherapy in advanced pancreaticcancer: Agiscad randomized phase ii study
    • Cascinu S, Berardi R, Sobrero A et al. Sorafenib does not improve efficacy of chemotherapy in advanced pancreaticcancer: aGISCAD randomized Phase II study. Dig. Liver Dis. 46(2), 182-186 (2014).
    • (2014) Dig. Liver Dis , vol.46 , Issue.2 , pp. 182-186
    • Cascinu, S.1    Berardi, R.2    Sobrero, A.3
  • 2
    • 84891960221 scopus 로고    scopus 로고
    • Close correlation between mek/erk and aurora-b signaling pathways in sustaining tumorigenic potential and radioresistance of gynecological cancer cell lines
    • Marampon F, Gravina GL, Popov VM et al. Close correlation between MEK/ERK and Aurora-B signaling pathways in sustaining tumorigenic potential and radioresistance of gynecological cancer cell lines. Int. J. Oncol. 44(1), 285-294 (2014).
    • (2014) Int. J. Oncol , vol.44 , Issue.1 , pp. 285-294
    • Marampon, F.1    Gravina, G.L.2    Popov, V.M.3
  • 3
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the asia-pacific region with advanced hepatocellular carcinoma: A phase iii randomised, double-blind, placebo-controlled trial
    • Cheng AL, Kang YK, Chen Z et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a Phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol. 10(1), 25-34 (2009).
    • (2009) Lancet Oncol , vol.10 , Issue.1 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3
  • 4
    • 84876974877 scopus 로고    scopus 로고
    • Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: Overall survival analysis and updated results from a randomised phase 3 trial
    • Motzer RJ, Escudier B, Tomczak P et al. Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised Phase 3 trial. Lancet Oncol. 14(6), 552-562 (2013).
    • (2013) Lancet Oncol , vol.14 , Issue.6 , pp. 552-562
    • Motzer, R.J.1    Escudier, B.2    Tomczak, P.3
  • 5
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • Llovet JM, Ricci S, Mazzaferro V et al. Sorafenib in advanced hepatocellular carcinoma. N. Engl. J. Med. 359(4), 378-390 (2008).
    • (2008) N. Engl. J. Med , vol.359 , Issue.4 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3
  • 6
    • 84887409830 scopus 로고    scopus 로고
    • Systemic therapy for hepatocellular carcinoma (hcc): From bench to bedside
    • Abdel-Rahman O. Systemic therapy for hepatocellular carcinoma (HCC): from bench to bedside. J. Egypt. Natl Canc. Inst. 25(4), 165-171 (2013).
    • (2013) J. Egypt. Natl Canc. Inst , vol.25 , Issue.4 , pp. 165-171
    • Abdel-Rahman, O.1
  • 8
    • 84890130605 scopus 로고    scopus 로고
    • Combination trans arterial chemoembolization (tace) plus sorafenib for the management of unresectable hepatocellular carcinoma: A systematic review of the literature
    • Abdel-Rahman O, Elsayed Z. Combination trans arterial chemoembolization (tace) plus sorafenib for the management of unresectable hepatocellular carcinoma: a systematic review of the literature. Dig. Dis. Sci. 58(12), 3389-3396 (2013).
    • (2013) Dig. Dis. Sci , vol.58 , Issue.12 , pp. 3389-3396
    • Abdel-Rahman, O.1    Elsayed, Z.2
  • 10
    • 84925548115 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The prisma statement
    • Moher D. Liberati A. Tetzlaff J et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J. Clin. Epidemiol. 62(10), 1006-1012 (2009).
    • (2009) J. Clin. Epidemiol , vol.62 , Issue.10 , pp. 1006-1012
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 11
    • 84860460071 scopus 로고    scopus 로고
    • Common toxicity criteria
    • National Cancer Institute. Common toxicity criteria. http://ctep.cancer.gov
    • National Cancer Institute
  • 12
    • 84879112772 scopus 로고    scopus 로고
    • A randomized phase ii trial of maintenance therapy with sorafenib in front-line ovarian carcinoma
    • Herzog TJ, Scambia G, Kim BG et al. A randomized Phase II trial of maintenance therapy with sorafenib in front-line ovarian carcinoma. Gynecol. Oncol. 130(1), 25-30 (2013).
    • (2013) Gynecol. Oncol , vol.130 , Issue.1 , pp. 25-30
    • Herzog, T.J.1    Scambia, G.2    Kim, B.G.3
  • 13
    • 79960805810 scopus 로고    scopus 로고
    • Phase iii study of sorafenib after transarterial chemoembolisation in japanese and korean patients with unresectable hepatocellular carcinoma
    • Kudo M, Imanaka K, Chida N et al. Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma. Eur. J. Cancer 47(14), 2117-2127 (2011).
    • (2011) Eur. J. Cancer , vol.47 , Issue.14 , pp. 2117-2127
    • Kudo, M.1    Imanaka, K.2    Chida, N.3
  • 14
    • 84872110165 scopus 로고    scopus 로고
    • A double-blind, randomised, placebo-controlled, phase iib study evaluating sorafenib in combination with paclitaxel as a first-line therapy in patients with her2-negative advanced breast cancer
    • Gradishar WJ, Kaklamani V, Sahoo TP et al. A double-blind, randomised, placebo-controlled, Phase IIb study evaluating sorafenib in combination with paclitaxel as a first-line therapy in patients with HER2-negative advanced breast cancer. Eur. J. Cancer 49(2), 312-322 (2013).
    • (2013) Eur. J. Cancer , vol.49 , Issue.2 , pp. 312-322
    • Gradishar, W.J.1    Kaklamani, V.2    Sahoo, T.P.3
  • 15
    • 84868107516 scopus 로고    scopus 로고
    • Baypan study: A double-blind phase iii randomized trial comparing gemcitabine plus sorafenib and gemcitabine plus placebo in patients with advanced pancreatic cancer
    • Gonçalves A, Gilabert M, François E et al. BAYPAN study: a double-blind Phase III randomized trial comparing gemcitabine plus sorafenib and gemcitabine plus placebo in patients with advanced pancreatic cancer. Ann. Oncol. 23(11), 2799-2805 (2012).
    • (2012) Ann. Oncol , vol.23 , Issue.11 , pp. 2799-2805
    • Gonçalves, A.1    Gilabert, M.2    François, E.3
  • 16
    • 43749110700 scopus 로고    scopus 로고
    • Double-blind randomized phase ii study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: A report from the 11715 study group
    • McDermott DF, Sosman JA, Gonzalez R et al. Double-blind randomized Phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group. J. Clin. Oncol. 26(13), 2178-2185 (2008).
    • (2008) J. Clin. Oncol , vol.26 , Issue.13 , pp. 2178-2185
    • McDermott, D.F.1    Sosman, J.A.2    Gonzalez, R.3
  • 17
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier B, Eisen T, Stadler WM et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N. Engl. J. Med. 356(2), 125-134 (2007).
    • (2007) N. Engl. J. Med , vol.356 , Issue.2 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 18
    • 77951639655 scopus 로고    scopus 로고
    • Phase iii study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer
    • Scagliotti G, Novello S, von Pawel J et al. Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer. J. Clin. Oncol. 28(11), 1835-1842 (2010).
    • (2010) J. Clin. Oncol , vol.28 , Issue.11 , pp. 1835-1842
    • Scagliotti, G.1    Novello, S.2    Von Pawel, J.3
  • 19
    • 79959306917 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, phase ii trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non-small-cell lung cancer
    • Spigel DR, Burris HA 3rd, Greco FA et al. Randomized, double-blind, placebo-controlled, Phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non-small-cell lung cancer. J. Clin. Oncol. 29(18), 2582-2589 (2011).
    • (2011) J. Clin. Oncol , vol.29 , Issue.18 , pp. 2582-2589
    • Spigel, D.R.1    Burris, H.A.2    Greco, F.A.3
  • 20
    • 84865721505 scopus 로고    scopus 로고
    • Phase iii, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer
    • Paz-Ares LG, Biesma B, Heigener D et al. Phase III, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer. J. Clin. Oncol. 30(25), 3084-3092 (2012).
    • (2012) J. Clin. Oncol , vol.30 , Issue.25 , pp. 3084-3092
    • Paz-Ares, L.G.1    Biesma, B.2    Heigener, D.3
  • 21
    • 84862988257 scopus 로고    scopus 로고
    • Sorafenib in combination with capecitabine: An oral regimen for patients with her2-negative locally advanced or metastatic breast cancer
    • Baselga J, Segalla JG, Roché H et al. Sorafenib in combination with capecitabine: an oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer. J. Clin. Oncol. 30(13), 1484-1491 (2012).
    • (2012) J. Clin. Oncol , vol.30 , Issue.13 , pp. 1484-1491
    • Baselga, J.1    Segalla, J.G.2    Roché, H.3
  • 22
    • 84857073184 scopus 로고    scopus 로고
    • Randomized phase ii trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma s0438
    • Margolin KA, Moon J, Flaherty LE et al. Randomized Phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438). Clin. Cancer Res. 18(4), 1129-1137 (2012).
    • (2012) Clin. Cancer Res , vol.18 , Issue.4 , pp. 1129-1137
    • Margolin, K.A.1    Moon, J.2    Flaherty, L.E.3
  • 23
    • 84864365642 scopus 로고    scopus 로고
    • A randomized phase ii of gemcitabine and sorafenib versus sorafenib alone in patients with metastaticpancreatic cancer
    • El-Khoueiry AB, Ramanathan RK, Yang DY et al. A randomized Phase II of gemcitabine and sorafenib versus sorafenib alone in patients with metastaticpancreatic cancer. Invest. New Drugs. 30(3), 1175-1183 (2012).
    • (2012) Invest. New Drugs , vol.30 , Issue.3 , pp. 1175-1183
    • El-Khoueiry, A.B.1    Ramanathan, R.K.2    Yang, D.Y.3
  • 24
    • 79959695837 scopus 로고    scopus 로고
    • Sorafenib in combination with erlotinib or with gemcitabine in elderly patients with advanced non-small-cell lung cancer: A randomized phase ii study
    • Gridelli C, Morgillo F, Favaretto A et al. Sorafenib in combination with erlotinib or with gemcitabine in elderly patients with advanced non-small-cell lung cancer: a randomized Phase II study. Ann. Oncol. 22(7), 1528-1534 (2011).
    • (2011) Ann. Oncol , vol.22 , Issue.7 , pp. 1528-1534
    • Gridelli, C.1    Morgillo, F.2    Favaretto, A.3
  • 25
    • 78349298645 scopus 로고    scopus 로고
    • Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: A randomized trial
    • Abou-Alfa GK, Johnson P, Knox JJ et al. Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial. JAMA 304(19), 2154-2160 (2010).
    • (2010) JAMA , vol.304 , Issue.19 , pp. 2154-2160
    • Abou-Alfa, G.K.1    Johnson, P.2    Knox, J.J.3
  • 26
    • 84888785384 scopus 로고    scopus 로고
    • Overall survival for sorafenib plus interleukin-2 compared with sorafenib alone in metastatic renal cell carcinoma (mrcc): Final results of the rosorc trial
    • Procopio G, Verzoni E, Bracarda S et al. Overall survival for sorafenib plus interleukin-2 compared with sorafenib alone in metastatic renal cell carcinoma (mRCC): final results of the ROSORC trial. Ann. Oncol. 24(12), 2967-2971 (2013).
    • (2013) Ann. Oncol , vol.24 , Issue.12 , pp. 2967-2971
    • Procopio, G.1    Verzoni, E.2    Bracarda, S.3
  • 27
    • 0041876133 scopus 로고    scopus 로고
    • Measuring inconsistency in meta-analyses
    • Higgins JP, Thompson SG, Deeks JJ et al. Measuring inconsistency in meta-analyses. BMJ 327(7414), 557-560 (2003).
    • (2003) BMJ , vol.327 , Issue.7414 , pp. 557-560
    • Higgins, J.P.1    Thompson, S.G.2    Deeks, J.J.3
  • 28
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin. Trials 7(3), 177-188 (1986).
    • (1986) Control Clin. Trials , vol.7 , Issue.3 , pp. 177-188
    • Dersimonian, R.1    Laird, N.2
  • 29
    • 2542523903 scopus 로고    scopus 로고
    • Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice
    • Yoshiji H, Kuriyama S, Yoshii J et al. Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice. Hepatology 39, 1517-1524 (2004).
    • (2004) Hepatology , vol.39 , pp. 1517-1524
    • Yoshiji, H.1    Kuriyama, S.2    Yoshii, J.3
  • 30
    • 84894289005 scopus 로고    scopus 로고
    • Sorafenib for egyptian patients with advanced hepatocellular carcinoma; Single center experience
    • Abdel-Rahman O, Abdelwahab M, Shaker M et al. Sorafenib for Egyptian patients with advanced hepatocellular carcinoma; single center experience. J. Egypt. Natl Cancer Inst. 26(1), 9-13 (2014).
    • (2014) J. Egypt. Natl Cancer Inst , vol.26 , Issue.1 , pp. 9-13
    • Abdel-Rahman, O.1    Abdelwahab, M.2    Shaker, M.3
  • 31
    • 84879526437 scopus 로고    scopus 로고
    • Sorafenib versus capecitabine in the management of advanced hepatocellular carcinoma
    • Abdel-Rahman O, Abdelwahab M, Shaker M et al. Sorafenib versus capecitabine in the management of advanced hepatocellular carcinoma. Med. Oncol. 30(3), 655 (2013).
    • (2013) Med. Oncol , vol.30 , Issue.3 , pp. 655
    • Abdel-Rahman, O.1    Abdelwahab, M.2    Shaker, M.3
  • 32
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N. Engl. J. Med. 356(2), 115-124 (2007).
    • (2007) N. Engl. J. Med , vol.356 , Issue.2 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 33
    • 84901607868 scopus 로고    scopus 로고
    • Sorafenib-based combination as a first line treatment for advanced hepatocellular carcinoma: A systematic review of the literature
    • Abdel-rahman O, Fouad M. Sorafenib-based combination as a first line treatment for advanced hepatocellular carcinoma: a systematic review of the literature. Crit. Rev. Oncol. Hematol. 91(1), 1-8 (2014).
    • (2014) Crit. Rev. Oncol. Hematol , vol.91 , Issue.1 , pp. 1-8
    • Abdel-Rahman, O.1    Fouad, M.2
  • 34
    • 77952310126 scopus 로고    scopus 로고
    • Risk of arterial thromboembolic events with sunitinib and sorafenib: A systematic review and meta-analysis of clinical trials
    • Choueiri TK, Schutz FA, Je Y et al. Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. J. Clin. Oncol. 28(13), 2280-2285 (2010).
    • (2010) J. Clin. Oncol , vol.28 , Issue.13 , pp. 2280-2285
    • Choueiri, T.K.1    Schutz, F.A.2    Je, Y.3
  • 35
    • 84858848994 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors
    • Schutz FA, Je Y, Richards CJ, Choueiri TK et al. Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. J. Clin. Oncol. 30(8), 871-877 (2012).
    • (2012) J. Clin. Oncol , vol.30 , Issue.8 , pp. 871-877
    • Schutz, F.A.1    Je, Y.2    Richards, C.J.3    Choueiri, T.K.4
  • 36
    • 84878602173 scopus 로고    scopus 로고
    • Venous thromboembolic events with vascular endothelial growth factor receptor tyrosine kinase inhibitors: A systematic review and meta-analysis of randomized clinical trials
    • Sonpavde G, Je Y, Schutz F et al. Venous thromboembolic events with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a systematic review and meta-analysis of randomized clinical trials. Crit. Rev. Oncol. Hematol. 87(1), 80-89 (2013).
    • (2013) Crit. Rev. Oncol. Hematol , vol.87 , Issue.1 , pp. 80-89
    • Sonpavde, G.1    Je, Y.2    Schutz, F.3
  • 37
    • 84884281930 scopus 로고    scopus 로고
    • Risk of hypertension in cancer patients treated with sorafenib: An updated systematic review and meta-analysis
    • Funakoshi T, Latif A, Galsky MD. Risk of hypertension in cancer patients treated with sorafenib: an updated systematic review and meta-analysis. J. Hum. Hypertens. 27(10), 601-611 (2013).
    • (2013) J. Hum. Hypertens , vol.27 , Issue.10 , pp. 601-611
    • Funakoshi, T.1    Latif, A.2    Galsky, M.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.