메뉴 건너뛰기




Volumn 87, Issue 1, 2013, Pages 80-89

Venous thromboembolic events with vascular endothelial growth factor receptor tyrosine kinase inhibitors: A systematic review and meta-analysis of randomized clinical trials

Author keywords

Approved; Meta analysis; Tyrosine kinase inhibitors; Vascular endothelial growth factor receptor; Venous thromboembolic events

Indexed keywords

AXITINIB; CARBOPLATIN; CISPLATIN; DOCETAXEL; DOXORUBICIN; GEMCITABINE; INTERFERON; LAPATINIB; PACLITAXEL; PAZOPANIB; PLACEBO; PREDNISONE; PROTEIN TYROSINE KINASE INHIBITOR; SORAFENIB; SUNITINIB; VANDETANIB; VASCULOTROPIN RECEPTOR;

EID: 84878602173     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2012.12.006     Document Type: Review
Times cited : (60)

References (43)
  • 2
    • 34548141828 scopus 로고    scopus 로고
    • Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab
    • Scappaticci F.A., Skillings J.R., Holden S.N., et al. Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. Journal of the National Cancer Institute 2007, 99:1232-1239.
    • (2007) Journal of the National Cancer Institute , vol.99 , pp. 1232-1239
    • Scappaticci, F.A.1    Skillings, J.R.2    Holden, S.N.3
  • 3
    • 79955587689 scopus 로고    scopus 로고
    • Venous thromboembolic events with chemotherapy plus bevacizumab: a pooled analysis of patients in randomized phase II and III studies
    • Hurwitz H.I., Saltz L.B., Van Cutsem E., et al. Venous thromboembolic events with chemotherapy plus bevacizumab: a pooled analysis of patients in randomized phase II and III studies. Journal of Clinical Oncology 2011, 29:1757-1764.
    • (2011) Journal of Clinical Oncology , vol.29 , pp. 1757-1764
    • Hurwitz, H.I.1    Saltz, L.B.2    Van Cutsem, E.3
  • 4
    • 56649123212 scopus 로고    scopus 로고
    • Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis
    • Nalluri S.R., Chu D., Keresztes R., Zhu X., Wu S. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis. JAMA: Journal of the American Medical Association 2008, 300:2277-2285.
    • (2008) JAMA: Journal of the American Medical Association , vol.300 , pp. 2277-2285
    • Nalluri, S.R.1    Chu, D.2    Keresztes, R.3    Zhu, X.4    Wu, S.5
  • 5
    • 85073893995 scopus 로고    scopus 로고
    • Risk of venous thromboembolism with bevacizumab in cancer patients: reply
    • Chu D., Wu S. Risk of venous thromboembolism with bevacizumab in cancer patients: reply. JAMA: Journal of the American Medical Association 2009, 301:1435-1436.
    • (2009) JAMA: Journal of the American Medical Association , vol.301 , pp. 1435-1436
    • Chu, D.1    Wu, S.2
  • 6
    • 84865617843 scopus 로고    scopus 로고
    • Risk of venous thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials
    • [abstract 348]
    • Schutz F.A., Richards J., Je Y., Bellmunt J., Choueiri T.K. Risk of venous thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. Genitourinary Cancer Symposium 2010, [abstract 348].
    • (2010) Genitourinary Cancer Symposium
    • Schutz, F.A.1    Richards, J.2    Je, Y.3    Bellmunt, J.4    Choueiri, T.K.5
  • 7
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: is blinding necessary?
    • Jadad A.R., Moore R.A., Carroll D., et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Controlled Clinical Trials 1996, 17:1-12.
    • (1996) Controlled Clinical Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 8
    • 84872011968 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
    • Liberati A., Altman D.G., Tetzlaff J., et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Journal of Clinical Epidemiology 2009, 62:e1-e34.
    • (2009) Journal of Clinical Epidemiology , vol.62
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3
  • 11
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg C.B., Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994, 50:1088-1101.
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 12
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M., Davey Smith G., Schneider M., Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315:629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 13
    • 77955874058 scopus 로고    scopus 로고
    • Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer
    • Monk B.J., Mas Lopez L., Zarba J.J., et al. Phase II, open-label study of pazopanib or lapatinib monotherapy compared with pazopanib plus lapatinib combination therapy in patients with advanced and recurrent cervical cancer. Journal of Clinical Oncology 2010, 28:3562-3569.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 3562-3569
    • Monk, B.J.1    Mas Lopez, L.2    Zarba, J.J.3
  • 14
    • 66249113517 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer
    • Horti J., Widmark A., Stenzl A., et al. A randomized, double-blind, placebo-controlled phase II study of vandetanib plus docetaxel/prednisolone in patients with hormone-refractory prostate cancer. Cancer Biotherapy and Radiopharmaceuticals 2009, 24:175-180.
    • (2009) Cancer Biotherapy and Radiopharmaceuticals , vol.24 , pp. 175-180
    • Horti, J.1    Widmark, A.2    Stenzl, A.3
  • 15
    • 79959286206 scopus 로고    scopus 로고
    • Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer
    • Rugo H.S., Stopeck A.T., Joy A.A., et al. Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer. Journal of Clinical Oncology 2011, 29:2459-2465.
    • (2011) Journal of Clinical Oncology , vol.29 , pp. 2459-2465
    • Rugo, H.S.1    Stopeck, A.T.2    Joy, A.A.3
  • 16
    • 77954035012 scopus 로고    scopus 로고
    • Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial
    • Herbst R.S., Sun Y., Eberhardt W.E., et al. Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial. Lancet Oncology 2010, 11:619-626.
    • (2010) Lancet Oncology , vol.11 , pp. 619-626
    • Herbst, R.S.1    Sun, Y.2    Eberhardt, W.E.3
  • 17
    • 34948844052 scopus 로고    scopus 로고
    • Phase II study of vandetanib or placebo in small-cell lung cancer patients after complete or partial response to induction chemotherapy with or without radiation therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20
    • Arnold A.M., Seymour L., Smylie M., et al. Phase II study of vandetanib or placebo in small-cell lung cancer patients after complete or partial response to induction chemotherapy with or without radiation therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20. Journal of Clinical Oncology 2007, 25:4278-4284.
    • (2007) Journal of Clinical Oncology , vol.25 , pp. 4278-4284
    • Arnold, A.M.1    Seymour, L.2    Smylie, M.3
  • 18
    • 56749102822 scopus 로고    scopus 로고
    • Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer
    • Heymach J.V., Paz-Ares L., De Braud F., et al. Randomized phase II study of vandetanib alone or with paclitaxel and carboplatin as first-line treatment for advanced non-small-cell lung cancer. Journal of Clinical Oncology 2008, 26:5407-5415.
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 5407-5415
    • Heymach, J.V.1    Paz-Ares, L.2    De Braud, F.3
  • 19
    • 79952036599 scopus 로고    scopus 로고
    • Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study
    • Kindler H.L., Ioka T., Richel D.J., et al. Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study. Lancet Oncology 2011, 12:256-262.
    • (2011) Lancet Oncology , vol.12 , pp. 256-262
    • Kindler, H.L.1    Ioka, T.2    Richel, D.J.3
  • 20
    • 33749505836 scopus 로고    scopus 로고
    • Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
    • Demetri G.D., van Oosterom A.T., Garrett C.R., et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 2006, 368:1329-1338.
    • (2006) Lancet , vol.368 , pp. 1329-1338
    • Demetri, G.D.1    van Oosterom, A.T.2    Garrett, C.R.3
  • 21
    • 67649909568 scopus 로고    scopus 로고
    • Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma
    • Hauschild A., Agarwala S.S., Trefzer U., et al. Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma. Journal of Clinical Oncology 2009, 27:2823-2830.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 2823-2830
    • Hauschild, A.1    Agarwala, S.S.2    Trefzer, U.3
  • 22
    • 68949145218 scopus 로고    scopus 로고
    • Overall survival and updated results for sunitinib compared with interferon Alfa in patients with metastatic renal cell carcinoma
    • Motzer R.J., Hutson T.E., Tomczak P., et al. Overall survival and updated results for sunitinib compared with interferon Alfa in patients with metastatic renal cell carcinoma. Journal of Clinical Oncology 2009, 27(22):3584-3590.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.22 , pp. 3584-3590
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 23
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon Alfa in metastatic renal-cell carcinoma
    • Motzer R.J., Hutson T.E., Tomczak P., et al. Sunitinib versus interferon Alfa in metastatic renal-cell carcinoma. New England Journal of Medicine 2007, 356:115-124.
    • (2007) New England Journal of Medicine , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 24
    • 77951639655 scopus 로고    scopus 로고
    • Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer
    • Scagliotti G., Novello S., von Pawel J., et al. Phase III study of carboplatin and paclitaxel alone or with sorafenib in advanced non-small-cell lung cancer. Journal of Clinical Oncology 2010, 28:1835-1842.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 1835-1842
    • Scagliotti, G.1    Novello, S.2    von Pawel, J.3
  • 25
    • 78349298645 scopus 로고    scopus 로고
    • Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial
    • Abou-Alfa G.K., Johnson P., Knox J.J., et al. Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial. JAMA: Journal of the American Medical Association 2010, 304:2154-2160.
    • (2010) JAMA: Journal of the American Medical Association , vol.304 , pp. 2154-2160
    • Abou-Alfa, G.K.1    Johnson, P.2    Knox, J.J.3
  • 26
    • 77958497505 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin with or without sorafenib in urothelial carcinoma (AUO-AB 31/05)
    • [abstract 4574]
    • Krege S., Rexer H., vom Dorp F., et al. Gemcitabine and cisplatin with or without sorafenib in urothelial carcinoma (AUO-AB 31/05). Journal of Clinical Oncology 2010, 28(Suppl.):15s. [abstract 4574].
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.SUPPL.
    • Krege, S.1    Rexer, H.2    vom Dorp, F.3
  • 27
    • 81255175385 scopus 로고    scopus 로고
    • Randomized, placebo-controlled, phase III trial of sunitinib in combination with prednisone (SU+P) versus prednisone (P) alone in men with progressive metastatic castration-resistant prostate cancer (mCRPC)
    • [abstract 4515]
    • Michaelson M.D., Oudard S., Ou Y., et al. Randomized, placebo-controlled, phase III trial of sunitinib in combination with prednisone (SU+P) versus prednisone (P) alone in men with progressive metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology 2011, 29(Suppl.). [abstract 4515].
    • (2011) Journal of Clinical Oncology , vol.29 , Issue.SUPPL.
    • Michaelson, M.D.1    Oudard, S.2    Ou, Y.3
  • 28
    • 84861720010 scopus 로고    scopus 로고
    • Vandetanib versus placebo in patients with advanced non-small-cell lung cancer after prior therapy with an epidermal growth factor receptor tyrosine kinase inhibitor: a randomized, double-blind phase III trial (ZEPHYR)
    • Lee J.S., Hirsh V., Park K., et al. Vandetanib versus placebo in patients with advanced non-small-cell lung cancer after prior therapy with an epidermal growth factor receptor tyrosine kinase inhibitor: a randomized, double-blind phase III trial (ZEPHYR). Journal of Clinical Oncology 2012, 30:1114-1121.
    • (2012) Journal of Clinical Oncology , vol.30 , pp. 1114-1121
    • Lee, J.S.1    Hirsh, V.2    Park, K.3
  • 29
    • 84857046020 scopus 로고    scopus 로고
    • A randomized, phase II study of pazopanib in castrate-sensitive prostate cancer: a University of Chicago Phase II Consortium/Department of Defense Prostate Cancer Clinical Trials Consortium study
    • Ward J.E., Karrison T., Chatta G., et al. A randomized, phase II study of pazopanib in castrate-sensitive prostate cancer: a University of Chicago Phase II Consortium/Department of Defense Prostate Cancer Clinical Trials Consortium study. Prostate Cancer and Prostatic Diseases 2012, 15:87-92.
    • (2012) Prostate Cancer and Prostatic Diseases , vol.15 , pp. 87-92
    • Ward, J.E.1    Karrison, T.2    Chatta, G.3
  • 30
    • 84861098484 scopus 로고    scopus 로고
    • Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial
    • van der Graaf W.T., Blay J.Y., Chawla S.P., et al. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 2012, 379:1879-1886.
    • (2012) Lancet , vol.379 , pp. 1879-1886
    • van der Graaf, W.T.1    Blay, J.Y.2    Chawla, S.P.3
  • 32
    • 43449115194 scopus 로고    scopus 로고
    • Development and validation of a predictive model for chemotherapy-associated thrombosis
    • Khorana A.A., Kuderer N.M., Culakova E., Lyman G.H., Francis C.W. Development and validation of a predictive model for chemotherapy-associated thrombosis. Blood 2008, 111:4902-4907.
    • (2008) Blood , vol.111 , pp. 4902-4907
    • Khorana, A.A.1    Kuderer, N.M.2    Culakova, E.3    Lyman, G.H.4    Francis, C.W.5
  • 33
    • 0036910386 scopus 로고    scopus 로고
    • The role of hydrogen peroxide in endothelial proliferative responses
    • Stone J.R., Collins T. The role of hydrogen peroxide in endothelial proliferative responses. Endothelium 2002, 9:231-238.
    • (2002) Endothelium , vol.9 , pp. 231-238
    • Stone, J.R.1    Collins, T.2
  • 34
    • 0035895711 scopus 로고    scopus 로고
    • Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
    • Zachary I., Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovascular Research 2001, 49:568-581.
    • (2001) Cardiovascular Research , vol.49 , pp. 568-581
    • Zachary, I.1    Gliki, G.2
  • 36
    • 34250365240 scopus 로고    scopus 로고
    • Mechanisms of adverse effects of anti-VEGF therapy for cancer
    • Kamba T., McDonald D.M. Mechanisms of adverse effects of anti-VEGF therapy for cancer. British Journal of Cancer 2007, 96:1788-1795.
    • (2007) British Journal of Cancer , vol.96 , pp. 1788-1795
    • Kamba, T.1    McDonald, D.M.2
  • 38
    • 80053973209 scopus 로고    scopus 로고
    • Hematologic toxicities in cancer patients treated with the multi-tyrosine kinase sorafenib: a meta-analysis of clinical trials
    • Schutz F.A., Je Y., Choueiri T.K. Hematologic toxicities in cancer patients treated with the multi-tyrosine kinase sorafenib: a meta-analysis of clinical trials. Critical Reviews in Oncology/Hematology 2011, 80:291-300.
    • (2011) Critical Reviews in Oncology/Hematology , vol.80 , pp. 291-300
    • Schutz, F.A.1    Je, Y.2    Choueiri, T.K.3
  • 40
    • 79957790694 scopus 로고    scopus 로고
    • Bevacizumab increases the risk of arterial ischemia: a large study in cancer patients with a focus on different subgroup outcomes
    • Schutz F.A., Je Y., Azzi G.R., Nguyen P.L., Choueiri T.K. Bevacizumab increases the risk of arterial ischemia: a large study in cancer patients with a focus on different subgroup outcomes. Annals of Oncology 2011, 22:1404-1412.
    • (2011) Annals of Oncology , vol.22 , pp. 1404-1412
    • Schutz, F.A.1    Je, Y.2    Azzi, G.R.3    Nguyen, P.L.4    Choueiri, T.K.5
  • 41
    • 77951269420 scopus 로고    scopus 로고
    • Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis of randomized controlled trials
    • Ranpura V., Hapani S., Chuang J., Wu S. Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis of randomized controlled trials. Acta Oncologica 2010, 49:287-297.
    • (2010) Acta Oncologica , vol.49 , pp. 287-297
    • Ranpura, V.1    Hapani, S.2    Chuang, J.3    Wu, S.4
  • 42
    • 84861732267 scopus 로고    scopus 로고
    • Incidence, risk factors and clinical implications of venous thromboembolism in cancer patients treated within the context of phase I studies: the 'SENDO experience'
    • Mandala M., Clerici M., Corradino I., et al. Incidence, risk factors and clinical implications of venous thromboembolism in cancer patients treated within the context of phase I studies: the 'SENDO experience'. Annals of Oncology 2012, 23:1416-1421.
    • (2012) Annals of Oncology , vol.23 , pp. 1416-1421
    • Mandala, M.1    Clerici, M.2    Corradino, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.