Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages

International Immunopharmacology

Volumn 25, Issue 1, 2015, Pages 199-206

  Sekhon Loodu, Satvir ^a   Ziaullah, ^a   Rupasinghe, H P Vasantha ^a,b  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

COX 2; Cytokines; Docosahexaenoic acid; Inflammation; Phloridzin; TNF

Indexed keywords

BIOLOGICAL MARKER; CYCLOOXYGENASE 2; DICLOFENAC; DOCOSAHEXAENOIC ACID; DOCOSAHEXAENOIC ACID ESTER OF PHLORIDZIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NIMESULIDE; PHENOL DERIVATIVE; PHLORETIN; PHLORIZIN; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; METHYL DOCOSAHEXAENOATE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; SULFONAMIDE;

ACYLATION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EXPOSURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INFLAMMATION; MACROPHAGE; MONOCYTE; PLATE COUNT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; CELL LINE; COMPARATIVE STUDY; DRUG EFFECTS; FRUIT; IMMUNOLOGY; MALUS; METABOLISM; SYNTHESIS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL DIFFERENTIATION; CELL LINE; CYCLOOXYGENASE INHIBITORS; CYTOKINES; DICLOFENAC; DOCOSAHEXAENOIC ACIDS; FRUIT; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MALUS; NF-KAPPA B; PHLORETIN; PHLORHIZIN; SULFONAMIDES;

EID: 84922669159     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.01.019     Document Type: Article

References (41)

1. X. Sun, H.P. Jones, N. Dobbs, S. Bodhankar, and J.W. Simecka Dendritic cells are the major antigen presenting cells in inflammatory lesions of murine mycoplasma respiratory disease PLoS One 8 2013 1 11
2. M. Sultani, A.M. Stringer, J.M. Bowen, and R.J. Gibson Anti-inflammatory cytokines: important immunoregulatory factors contributing to chemotherapy-induced gastrointestinal mucositis Chemother Res Pract 2012 1 11
3. F. Emanuela, M. Grazia, D.R. Marco, L.M. Paola, F. Giorgio, and B. Marco Inflammation as a link between obesity and metabolic syndrome J Nutr Metab 2012 1 7
4. B. Edalat, F. Sharifi, Z. Badamchizadeh, A. Hossein-Nezhad, B. Larijani, and M. Mirarefin Association of metabolic syndrome with inflammatory mediators in women with previous gestational diabetes mellitus J Diabet Metab Disord 12 2013 1 8
5. M.H. Pan, C.S. Laia, and C.T. Ho Anti-inflammatory activity of natural dietary flavonoids Food Funct 1 2010 15 31
6. K.L. Khanduja, K.K. Sohi, C.M. Pathak, and G. Kaushik Nimesulide inhibits lipopolysaccharide-induced production of superoxide anions and nitric oxide and iNOS expression in alveolar macrophages Life Sci 78 2006 1662 1669
7. A. Mouthys-Mickalad, G. Deby-Dupont, J.M. Dogne, X. de Leval, S. Kohnen, and R. Navet Effects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1) Biochem Biophys Res Commun 325 2004 1122 1130
8. A. Lanas, J. Tornero, and J.L. Zamorano Assessment of gastrointestinal and cardiovascular risk in patients with osteoarthritis who require NSAIDs: the LOGICA study Ann Rheum Dis 698 2010 1453 1458
9. O. Coskun, M. Kanter, A. Korkmaz, and S. Oter Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas Pharmacol Res 51 2005 117 123
10. S.H. Thilakarathna, and H.P.V. Rupasinghe Anti-atherosclerotic effects of fruit bioactive compounds: a review of current scientific evidence Can J Plant Sci 92 2012 407 419
11. P.A. Ruiz, A. Braune, G. Holzlwimmer, L. Quintanilla-Fend, and D. Haller Quercetin inhibits TNF-induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells J Nutr 137 2007 1208 1215
12. Y.W. Chin, M.J. Balunas, H.B. Chai, and A.D. Kinghorn Drug discovery from natural sources AAPSJ 8 2006 239 253
13. M. Galvez-Llompart, R. Zanni, and R. García-Domenech Modeling natural anti-inflammatory compounds by molecular topology Int J Mol Sci 12 2011 9481 9503
14. J. Gonzalez-Gallego, M.V. Garcia-Mediavilla, S. Sanchez-Campos, and M.J. Tunon Fruit polyphenols, immunity and inflammation Br J Nutr 104 2010 S15 S27
15. C. Puel, A. Quintin, J. Mathey, C. Obled, M. Davicco, and P. Lebecque Prevention of bone loss by phloridzin, an apple polyphenol, in ovariectomized rats under inflammation conditions Calcif Tissue Int 77 2005 311 318
16. W.T. Chang, W.C. Huang, and C.J. Liou Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages Food Chem 134 2012 972 979
17. H.P.V. Rupasinghe, and A. Yasmin Inhibition of oxidation of aqueous emulsions of omega-3 fatty acids and fish oil by phloretin and phloridzin Molecules 15 2010 251 257
18. I. Rudkowska Fish oils for cardiovascular disease: impact on diabetes Maturitas 67 2010 25 28
19. M. Nakakuki, H. Kawano, T. Notsu, and K. Imada Eicosapentaenoic acid suppresses palmitate-induced cytokine production by modulating long-chain acyl-CoA synthetase 1 expression in Human THP-1 macrophages Atherosclerosis 227 2013 289 296
20. K. Ishihara, and N. Nakajima Structural aspects of acylated plant pigments: stabilization of flavonoid glucosides and interpretation of their functions J Mol Catal B Enzym 23 2003 411 417
21. J. Viskupicova, M. Danihelov, M. Ondrejovic, T. Liptaj, and E. Sturdik Lipophilic rutin derivatives for antioxidant protection of oil-based foods Food Chem 123 2010 45 50
22. Ziaullah, K.S. Bhullar, S.N. Warnakulasuriya, and H.P.V. Rupasinghe Biocatalytic synthesis, structural elucidation, antioxidant capacity and tyrosinase inhibition activity of long chain fatty acid acylated derivatives of phloridzin and isoquercitrin Bioorg Med Chem 21 2013 684 692
23. S.V.G. Nair, Ziaullah, and H.P.V. Rupasinghe Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression PLoS One 9 2014 e107149
24. T.L. Riss, and R.A. Moravec Use of multiple assay endpoints to investigate the effects of incubation time, dose of toxin, and plating density in cell-based cytotoxicity assays Assay Drug Dev Technol 2 2004 51 62
25. W.A. Boisvert The participation of inflammatory cells in atherosclerosis Drugs Today 37 2001 173 179
26. H.W. Wang, T. Wu, J.Y. Qi, Y.Q. Wang, X.P. Luo, and Q. Ning Salidroside attenuates LPS-stimulated activation of THP-1 cell-derived macrophages through down-regulation of MAPK/NF-kB signaling pathways J Huazhong Univ Sci Technolog Med Sci 33 2013 463 469
27. P. Libby, P.M. Ridker, and G.K. Hansson Progress and challenges in translating the biology of atherosclerosis Nature 473 2011 317 325
28. E.A. Liehn, A. Zernecke, O. Postea, and C. Weber Chemokines: inflammatory mediators of atherosclerosis Arch Physiol Biochem 112 2006 229 238
29. E.A. Miles, F.A. Wallace, and P.C. Calder Dietary fish oil reduces intercellular adhesion molecule 1 and scavenger receptor expression on murine macrophages Atherosclerosis 152 2000 43 50
30. H. Yamada, M. Yoshida, Y. Nakano, T. Suganami, N. Satoh, and T. Mita In vivo and in vitro inhibition of monocyte adhesion to endothelial cells and endothelial adhesion molecules by eicosapentaenoic acid Arterioscler Thromb Vasc Biol 28 2008 2173 2179
31. A.F. McGettrick, and L.A. O'Neill Regulators of TLR4 signaling by endotoxins Subcell Biochem 53 2010 153 171
32. H. Wang, Q. Hao, Q.R. Li, X.W. Yan, S. Ye, and Y.S. Li ω-3 polyunsaturated fatty acids affect lipopolysaccharide-induced maturation of dendritic cells through mitogen-activated protein kinases p38 Nutrition 23 2007 474 482
33. P.C. Calder N-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases Am J Clin Nutr 83 2006 1505S 1519S
34. Y. Zhong, Y.S. Chiou, M.H. Pan, and F. Shahidi Anti-inflammatory activity of lipophilic epigallocatechin gallate (EGCG) derivatives in LPS-stimulated murine macrophages Food Chem 134 2012 742 748
35. H.K. Biesalski Polyphenols and inflammation: basic interactions Curr Opin Clin Nutr Metab Care 10 2007 724 728
36. J. Lu, J.S. Wang, and L.Y. Kong Anti-inflammatory effects of Huang-Lian-Jie-Du decoction, its two fractions and four typical compounds J Ethnopharmacol 134 2011 911 918
37. P. Clifton Dietary fatty acids and inflammation Nutr. Diet. 66 2009 7 11
38. S.R. Kang, K.I. Park, H.S. Park, D.H. Lee, J.A. Kim, and A. Nagappan Anti-inflammatory effect of flavonoids isolated from Korea Citrus aurantium L. on lipopolysaccharide-induced mouse macrophage RAW 264.7 cells by blocking of nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways Food Chem 129 2011 1721 1728
39. A. Mullen, C.E. Loscher, and H.M. Roche Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages J Nutr Biochem 21 2010 444 450
40. G.A. Bonaterra, E.U. Heinrich, O. Kelber, D. Weiser, J. Metz, and R. Kinscherf Anti-inflammatory effects of the willow bark extract STW 33-I (Proaktiv(®)) in LPS-activated human monocytes and differentiated macrophages Phytomedicine 17 2010 1106 1113
41. B. Zingarelli, M. Sheehan, and H.R. Wong Nuclear factor-kappa B as a therapeutic target in critical care medicine Crit Care Med 31 2003 S105 S111