Antinociceptive effects of sinomenine in a rat model of neuropathic pain

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Zhu, Qing ^a   Sun, Yuehua ^a   Zhu, Jie ^a   Fang, Tian ^a   Zhang, Wei ^a   Li, Jun Xu ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; MORPHINAN DERIVATIVE; SINOMENINE;

ANIMAL; ANIMAL BEHAVIOR; DOSE RESPONSE; DRUG EFFECTS; HYPERALGESIA; MALE; NEURALGIA; PAIN MEASUREMENT; PATHOPHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; TOUCH; TREATMENT OUTCOME;

ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERALGESIA; MALE; MORPHINANS; NEURALGIA; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; TOUCH; TREATMENT OUTCOME;

EID: 84922658820     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep07270     Document Type: Article

References (23)

1. Mayeda, H. The release of histamine by sinomenine. Jpn. J. Pharmacol 3, 62-72 (1953).
2. Yamasaki, H. Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. Acta Med. Okayama 30, 1-20 (1976).
3. Wang, Y., Zhou, L. & Li, R. [Study progress in Sinomenium acutum (Thunb.) Rehd. et Wils]. Zhong Yao Cai 25, 209-211 (2002).
4. Qian, L. et al. Sinomenine, a natural dextrorotatory morphinan analog, is antiinflammatory and neuroprotective through inhibition of microglial NADPH oxidase. J. Neuroinflammation 4, 23 (2007).
5. Zhao, X. X., Peng, C., Zhang, H. & Qin, L. P. Sinomenium acutum: a review of chemistry, pharmacology, pharmacokinetics, and clinical use. Pharm. Biol. 50, 1053-1061 (2012).
6. Gao, T., Hao, J., Wiesenfeld-Hallin, Z., Wang, D. Q. & Xu, X. J. Analgesic effect of sinomenine in rodents after inflammation and nerve injury. Eur. J. Pharmacol. 721, 5-11 (2013).
7. Li, J. X. Pain and depression comorbidity: A preclinical perspective. Behav. Brain Res. 276, 92-98 (2014).
8. Smith, B. H. & Torrance, N. Epidemiology of neuropathic pain and its impact on quality of life. Curr. Pain Headache Rep. 16, 191-198 (2012).
9. Muthuraman, A., Singh, N., Jaggi, A. S. & Ramesh, M. Drug therapy of neuropathic pain: current developments and future perspectives. Curr. Drug Targets 15, 210-253 (2014).
10. Boronat, M. A., Olmos, G. & Garcia-Sevilla, J. A. Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I2-imidazoline ligands. Br. J. Pharmacol. 125, 175-185 (1998).
11. Moreno-Rocha, L. A., Dominguez-Ramirez, A. M., Cortes-Arroyo, A. R., Bravo, G. & Lopez-Munoz, F. J. Antinociceptive effects of tramadol in co-Administration with metamizol after single and repeated administrations in rats. Pharmacol. Biochem. Behav. 103, 1-5 (2012).
12. Wakley, A. A., Wiley, J. L. & Craft, R. M. Sex differences in antinociceptive tolerance to delta-9-Tetrahydrocannabinol in the rat. Drug Alcohol Depend. 143, 22-28 (2014).
13. Gao, T. L., Shi, T., Wang, D., Wiesenfeld-Hallin, Z. & Xu, X. J. Repeated sinomenineadministrationalleviateschronicneuropathic pain-like behavioursinrodentswithoutproducingtolerance. Scandinavian J. Pain 5, 249-255 (2014).
14. Zhao, X. et al. Chronic curcumin treatment normalizes depression-like behaviors in mice with mononeuropathy: involvement of supraspinal serotonergic system and GABA receptor. Psychopharmacology (Berl) 231, 2171-2187 (2014).
15. Jesse, C. R., Wilhelm, E. A. & Nogueira, C. W. Depression-like behavior and mechanical allodynia are reduced by bis selenide treatment in mice with chronic constriction injury: a comparison with fluoxetine, amitriptyline, and bupropion. Psychopharmacology (Berl) 212, 513-522 (2010).
16. Wang, M. H. et al. Activation of opioid mu-receptor by sinomenine in cell and mice. Neurosci Lett 443, 209-212 (2008).
17. Colpaert, F. C. 5-HT(1A) receptor activation: new molecular and neuroadaptive mechanisms of pain relief. Curr. Opin. Investigational Drugs 7, 40-47 (2006).
18. McCarson, K. E. & Enna, S. J. GABA Pharmacology: The Search for Analgesics. Neurochem. Res. 39, 1948-1963 (2014).
19. Bennett, G. J. & Xie, Y. K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33, 87-107 (1988).
20. Zhu, Q. et al. Antinociceptive effects of curcumin in a rat model of postoperative pain. Sci. Rep. 4, 4932 (2014).
21. Yalcin, I. et al. beta(2)-Adrenoceptors are critical for antidepressant treatment of neuropathic pain. Ann. Neurol. 65, 218-225 (2009).
22. Porsolt, R. D., Anton, G., Blavet, N. & Jalfre, M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur. J. Pharmacol. 47, 379-391 (1978).
23. Cryan, J. F., Valentino, R. J. & Lucki, I. Assessing substrates underlying the behavioral effects of antidepressants using themodified rat forced swimming test. Neurosci. Biobehav. Rev. 29, 547-569 (2005).