In vitro lead exposure changes DNA methylation and expression of IGF2 and PEG1/MEST

Toxicology in Vitro

Volumn 29, Issue 3, 2015, Pages 544-550

  Nye, Monica D ^a,b   Hoyo, Cathrine ^c   Murphy, Susan K ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Bisulfite pyrosequencing; DNA methylation; Epigenetics; Insulin like growth factor 2 (IGF2); Lead acetate; Paternally expressed gene 1 mesoderm specific transcript (PEG1 MEST)

Indexed keywords

LEAD ACETATE; SOMATOMEDIN B; LEAD; MESODERM SPECIFIC TRANSCRIPT PROTEIN; ORGANOMETALLIC COMPOUND; PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; ENVIRONMENTAL EXPOSURE; EPIGENETICS; GENE EXPRESSION; GENETIC ANALYSIS; GENOME IMPRINTING; HUMAN; HUMAN CELL; IGF2 GENE; IN VITRO STUDY; PEG1 GENE; PHENOTYPE; PROMOTER REGION; PYROSEQUENCING; REGULATOR GENE; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM;

DNA METHYLATION; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR II; LEAD; ORGANOMETALLIC COMPOUNDS; PROTEINS;

EID: 84922646871     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.01.002     Document Type: Article

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