Selenite-induced toxicity in cancer cells is mediated by metabolic generation of endogenous selenium nanoparticles

Journal of Proteome Research

Volumn 14, Issue 2, 2015, Pages 1127-1136

  Bao, Peng ^a,e   Chen, Zheng ^a   Tai, Ren Zhong ^b   Shen, Han Ming ^c   Martin, Francis L ^d   Zhu, Yong Guan ^a,e  

^a RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

^b SHANGHAI INSTITUTE OF APPLIED PHYSICS   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d LANCASTER UNIVERSITY   (United Kingdom)

^e INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

chemoprevention; glycolysis; heat shock proteins; mitochondrial dysfunction; selenite; selenium nanoparticles; self assembly; tubulin

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHAPERONIN 60; CYTOCHROME C; CYTOCHROME C OXIDASE; GLYCOLYTIC ENZYME; HEAT SHOCK PROTEIN 90; LACTATE DEHYDROGENASE; PROTEIN BAD; PROTEIN BAX; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PYRUVATE KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SELENITE; SELENIUM NANOPARTICLE; TUBULIN; METAL NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SELENIOUS ACID; SELENIUM;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CYTOTOXICITY; DEPOLYMERIZATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA STRAND BREAKAGE; GASTRIC CANCER CELL LINE; GLYCOLYSIS; HUMAN; HUMAN CELL; MICROTUBULE; MICROTUBULE ASSEMBLY; NON SMALL CELL LUNG CANCER; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RNA SEQUENCE; STOMACH CARCINOMA; DNA DAMAGE; DRUG EFFECTS; METABOLISM; POLYMERIZATION; TUMOR CELL LINE;

AUTOPHAGY; CELL LINE, TUMOR; DNA DAMAGE; GLYCOLYSIS; HUMANS; METAL NANOPARTICLES; POLYMERIZATION; REACTIVE OXYGEN SPECIES; SELENIOUS ACID; SELENIUM;

EID: 84922641050     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr501086e     Document Type: Article

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