Structures and characterization of digoxin- And bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 6, 2015, Pages 1755-1760

  Laursen, Mette ^a,b,d   Gregersen, Jonas Lindholt ^a,c   Yatime, Laure ^a,c   Nissen, Poul ^a,b,c   Fedosova, Natalya U ^a,b,d  

^a DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Cardiac glycosides; Inhibitor; Na K ATPase; Phosphoenzyme; Structure

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BUFALIN; DIGOXIN; OUABAIN;

ARTICLE; BINDING KINETICS; BINDING SITE; CATION EXCHANGE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG BINDING; GLYCOSYLATION; PRIORITY JOURNAL;

STROPHANTHUS GRATUS;

EID: 84922633960     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1422997112     Document Type: Article

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