Digoxin derivatives with enhanced selectivity for the α2 isoform of Na, K-ATPase: Effects on intraocular pressure in rabbits

Journal of Biological Chemistry

Volumn 289, Issue 30, 2014, Pages 21153-21162

  Katz, Adriana ^a   Tal, Daniel M ^a   Heller, Dan ^b   Haviv, Haim ^a   Rabah, Bilal ^c   Barkana, Yaniv ^b   Marcovich, Arie L ^c   Karlish, Steven J D ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b ASSAF HAROFEH MEDICAL CENTER   (Israel)

^c KAPLAN HOSPITAL   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

SUGARS;

4-AMINOPYRIDINE; ADENOSINE RECEPTOR; INTRA OCULAR PRESSURE; OCULAR HYPERTENSION; PERIODATE OXIDATION; PIGMENTED CELLS; REDUCTIVE AMINATION; SYSTEMIC TOXICITIES;

SODIUM;

4 AMINOPYRIDINE; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR ANTAGONIST; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); DIGOXIN; ENZYME INHIBITOR; ISOENZYME; POTASSIUM CHANNEL BLOCKING AGENT;

ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; HUMAN; INTRAOCULAR PRESSURE; METABOLISM; OCULAR HYPERTENSION; RABBIT; TOPICAL DRUG ADMINISTRATION;

4-AMINOPYRIDINE; ADENOSINE A3 RECEPTOR ANTAGONISTS; ADMINISTRATION, TOPICAL; ANIMALS; DIGOXIN; ENZYME INHIBITORS; HUMANS; INTRAOCULAR PRESSURE; ISOENZYMES; OCULAR HYPERTENSION; POTASSIUM CHANNEL BLOCKERS; RABBITS; RECEPTOR, ADENOSINE A3; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84905404567     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.557629     Document Type: Article

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