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Volumn 2, Issue , 2015, Pages 39-45

Using molecular genetic information to infer causality in observational data: Mendelian randomisation

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; DNA;

EID: 84922597885     PISSN: None     EISSN: 23521546     Source Type: Journal    
DOI: 10.1016/j.cobeha.2014.08.002     Document Type: Review
Times cited : (1)

References (42)
  • 6
    • 79953246461 scopus 로고    scopus 로고
    • Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake
    • Fowler C.D., Lu Q., Johnson P.M., Marks M.J., Kenny P.J. Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake. Nature 2011, 471:597-601.
    • (2011) Nature , vol.471 , pp. 597-601
    • Fowler, C.D.1    Lu, Q.2    Johnson, P.M.3    Marks, M.J.4    Kenny, P.J.5
  • 7
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
    • Lawlor D.A., Harbord R.M., Sterne J.A., Timpson N., Davey Smith G. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med 2008, 27:1133-1163.
    • (2008) Stat Med , vol.27 , pp. 1133-1163
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.3    Timpson, N.4    Davey Smith, G.5
  • 8
    • 36849073200 scopus 로고    scopus 로고
    • Persistence of contradicted claims in the literature
    • Tatsioni A., Bonitsis N.G., Ioannidis J.P. Persistence of contradicted claims in the literature. JAMA 2007, 298:2517-2526.
    • (2007) JAMA , vol.298 , pp. 2517-2526
    • Tatsioni, A.1    Bonitsis, N.G.2    Ioannidis, J.P.3
  • 9
    • 0037322022 scopus 로고    scopus 로고
    • 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?
    • Davey Smith G., Ebrahim S. 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?. Int J Epidemiol 2003, 32:1-22.
    • (2003) Int J Epidemiol , vol.32 , pp. 1-22
    • Davey Smith, G.1    Ebrahim, S.2
  • 10
    • 18444405551 scopus 로고    scopus 로고
    • What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?
    • Davey Smith G., Ebrahim S. What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?. BMJ 2005, 330:1076-1079.
    • (2005) BMJ , vol.330 , pp. 1076-1079
    • Davey Smith, G.1    Ebrahim, S.2
  • 11
    • 78149383523 scopus 로고    scopus 로고
    • Mendelian randomization for strengthening causal inference in observational studies: application to gene×environment interactions
    • Davey Smith G. Mendelian randomization for strengthening causal inference in observational studies: application to gene×environment interactions. Perspect Psychol Sci 2010, 5:527-545.
    • (2010) Perspect Psychol Sci , vol.5 , pp. 527-545
    • Davey Smith, G.1
  • 12
    • 38049023073 scopus 로고    scopus 로고
    • Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology
    • Davey Smith G., Lawlor D.A., Harbord R., Timpson N., Day I., Ebrahim S. Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med 2007, 4:e352.
    • (2007) PLoS Med , vol.4 , pp. e352
    • Davey Smith, G.1    Lawlor, D.A.2    Harbord, R.3    Timpson, N.4    Day, I.5    Ebrahim, S.6
  • 14
    • 84883170439 scopus 로고    scopus 로고
    • Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
    • Lawlor D.A., Nordestgaard B.G., Benn M., Zuccolo L., Tybjaerg-Hansen A., Davey Smith G. Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study. Eur Heart J 2013, 34:2519-2528.
    • (2013) Eur Heart J , vol.34 , pp. 2519-2528
    • Lawlor, D.A.1    Nordestgaard, B.G.2    Benn, M.3    Zuccolo, L.4    Tybjaerg-Hansen, A.5    Davey Smith, G.6
  • 16
    • 79960447071 scopus 로고    scopus 로고
    • Smoking is associated with, but does not cause, depressed mood in pregnancy-a mendelian randomization study
    • Lewis S.J., Araya R., Davey Smith G., Freathy R., Gunnell D., Palmer T., Munafo M. Smoking is associated with, but does not cause, depressed mood in pregnancy-a mendelian randomization study. PLoS One 2011, 6:e21689.
    • (2011) PLoS One , vol.6 , pp. e21689
    • Lewis, S.J.1    Araya, R.2    Davey Smith, G.3    Freathy, R.4    Gunnell, D.5    Palmer, T.6    Munafo, M.7
  • 18
    • 84870330686 scopus 로고    scopus 로고
    • Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight
    • Tyrrell J., Huikari V., Christie J.T., Cavadino A., Bakker R., Brion M.J., Geller F., Paternoster L., Myhre R., Potter C., et al. Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight. Hum Mol Genet 2012, 21:5344-5358.
    • (2012) Hum Mol Genet , vol.21 , pp. 5344-5358
    • Tyrrell, J.1    Huikari, V.2    Christie, J.T.3    Cavadino, A.4    Bakker, R.5    Brion, M.J.6    Geller, F.7    Paternoster, L.8    Myhre, R.9    Potter, C.10
  • 19
    • 1942436221 scopus 로고    scopus 로고
    • Mendelian randomization: prospects, potentials, and limitations
    • Davey Smith G., Ebrahim S. Mendelian randomization: prospects, potentials, and limitations. Int J Epidemiol 2004, 33:30-42.
    • (2004) Int J Epidemiol , vol.33 , pp. 30-42
    • Davey Smith, G.1    Ebrahim, S.2
  • 20
    • 84906838227 scopus 로고    scopus 로고
    • Mendelian randomization: genetic anchors for causal inference in epidemiological studies
    • Davey Smith G., Hemani G. Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet 2014.
    • (2014) Hum Mol Genet
    • Davey Smith, G.1    Hemani, G.2
  • 21
    • 84884973036 scopus 로고    scopus 로고
    • Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators
    • Pierce B.L., Burgess S. Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators. Am J Epidemiol 2013, 178:1177-1184.
    • (2013) Am J Epidemiol , vol.178 , pp. 1177-1184
    • Pierce, B.L.1    Burgess, S.2
  • 22
    • 84858648623 scopus 로고    scopus 로고
    • Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
    • Relton C.L., Davey Smith G. Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int J Epidemiol 2012, 41:161-176.
    • (2012) Int J Epidemiol , vol.41 , pp. 161-176
    • Relton, C.L.1    Davey Smith, G.2
  • 26
    • 84870284276 scopus 로고    scopus 로고
    • Causal graphical models in systems genetics: a unified framework for joint inference of causal network and genetic architecture for correlated phenotypes
    • Neto E.C., Keller M.P., Attie A.D., Yandell B.S. Causal graphical models in systems genetics: a unified framework for joint inference of causal network and genetic architecture for correlated phenotypes. Ann Appl Stat 2010, 4:320-339.
    • (2010) Ann Appl Stat , vol.4 , pp. 320-339
    • Neto, E.C.1    Keller, M.P.2    Attie, A.D.3    Yandell, B.S.4
  • 27
    • 84884793216 scopus 로고    scopus 로고
    • Power and sample size calculations for Mendelian randomization studies using one genetic instrument
    • Freeman G., Cowling B.J., Schooling C.M. Power and sample size calculations for Mendelian randomization studies using one genetic instrument. Int J Epidemiol 2013, 42:1157-1163.
    • (2013) Int J Epidemiol , vol.42 , pp. 1157-1163
    • Freeman, G.1    Cowling, B.J.2    Schooling, C.M.3
  • 28
    • 84886426512 scopus 로고    scopus 로고
    • Calculating statistical power in Mendelian randomization studies
    • Brion M.J., Shakhbazov K., Visscher P.M. Calculating statistical power in Mendelian randomization studies. Int J Epidemiol 2013, 42:1497-1501.
    • (2013) Int J Epidemiol , vol.42 , pp. 1497-1501
    • Brion, M.J.1    Shakhbazov, K.2    Visscher, P.M.3
  • 29
    • 84902684375 scopus 로고    scopus 로고
    • Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome
    • Burgess S. Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome. Int J Epidemiol 2014, 43:922-929.
    • (2014) Int J Epidemiol , vol.43 , pp. 922-929
    • Burgess, S.1
  • 30
    • 77952484063 scopus 로고    scopus 로고
    • Mendelian randomization as applied to coronary heart disease, including recent advances incorporating new technology
    • Lewis S.J. Mendelian randomization as applied to coronary heart disease, including recent advances incorporating new technology. Circ Cardiovasc Genet 2010, 3:109-117.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 109-117
    • Lewis, S.J.1
  • 31
    • 84896722557 scopus 로고    scopus 로고
    • Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates
    • Taylor A.E., Davies N.M., Ware J.J., Vanderweele T., Davey Smith G., Munafo M.R. Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates. Econ Hum Biol 2014, 13:99-106.
    • (2014) Econ Hum Biol , vol.13 , pp. 99-106
    • Taylor, A.E.1    Davies, N.M.2    Ware, J.J.3    Vanderweele, T.4    Davey Smith, G.5    Munafo, M.R.6
  • 34
    • 41549104622 scopus 로고    scopus 로고
    • Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach
    • Chen L., Davey Smith G., Harbord R.M., Lewis S.J. Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med 2008, 5:e52.
    • (2008) PLoS Med , vol.5 , pp. e52
    • Chen, L.1    Davey Smith, G.2    Harbord, R.M.3    Lewis, S.J.4
  • 35
    • 84856718639 scopus 로고    scopus 로고
    • Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions
    • Glymour M.M., Tchetgen E.J., Robins J.M. Credible Mendelian randomization studies: approaches for evaluating the instrumental variable assumptions. Am J Epidemiol 2012, 175:332-339.
    • (2012) Am J Epidemiol , vol.175 , pp. 332-339
    • Glymour, M.M.1    Tchetgen, E.J.2    Robins, J.M.3
  • 37
    • 84889861295 scopus 로고    scopus 로고
    • Using mendelian randomisation to infer causality in depression and anxiety research
    • Gage S.H., Davey Smith G., Zammit S., Hickman M., Munafo M.R. Using mendelian randomisation to infer causality in depression and anxiety research. Depress Anxiety 2013, 30:1185-1193.
    • (2013) Depress Anxiety , vol.30 , pp. 1185-1193
    • Gage, S.H.1    Davey Smith, G.2    Zammit, S.3    Hickman, M.4    Munafo, M.R.5
  • 38
    • 79955576466 scopus 로고    scopus 로고
    • Bias in causal estimates from Mendelian randomization studies with weak instruments
    • Burgess S., Thompson S.G. Bias in causal estimates from Mendelian randomization studies with weak instruments. Stat Med 2011, 30:1312-1323.
    • (2011) Stat Med , vol.30 , pp. 1312-1323
    • Burgess, S.1    Thompson, S.G.2
  • 39
    • 77952858616 scopus 로고    scopus 로고
    • Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables
    • Burgess S., Thompson S.G., CRP-CHD-Genetics-Collaboration Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables. Stat Med 2010, 29:1298-1311.
    • (2010) Stat Med , vol.29 , pp. 1298-1311
    • Burgess, S.1    Thompson, S.G.2
  • 40
    • 84874962114 scopus 로고    scopus 로고
    • Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies
    • Harbord R.M., Didelez V., Palmer T.M., Meng S., Sterne J.A., Sheehan N.A. Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies. Stat Med 2013, 32:1246-1258.
    • (2013) Stat Med , vol.32 , pp. 1246-1258
    • Harbord, R.M.1    Didelez, V.2    Palmer, T.M.3    Meng, S.4    Sterne, J.A.5    Sheehan, N.A.6
  • 42
    • 82455172054 scopus 로고    scopus 로고
    • Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis
    • Ware J.J., van den Bree M.B., Munafo M.R. Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis. Nicotine Tob Res 2011, 13:1167-1175.
    • (2011) Nicotine Tob Res , vol.13 , pp. 1167-1175
    • Ware, J.J.1    van den Bree, M.B.2    Munafo, M.R.3


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