Polygonum cuspidatum and its active components inhibit replication of the influenza virus through Toll-like receptor 9-induced interferon beta expression

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Lin, Chao Jen ^a,b,c   Lin, Hui Ju ^d,e   Chen, Ter Hsin ^f   Hsu, Yu An ^g   Liu, Chin San ^h   Hwang, Guang Yuh ^b   Wan, Lei ^d,e,i  

^a Department of Pediatrics Changhua Christian Children's Hospital ^*  (Taiwan)

^b TUNGHAI UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

^f NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^g NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^h CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

ⁱ ASIA UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; EMODIN; RESVERATROL; TOLL LIKE RECEPTOR 9; PLANT EXTRACT;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLUENZA A VIRUS A WSN 33 H1N1; INFLUENZA VIRUS A H1N1; LUCIFERASE ASSAY; NONHUMAN; POLYGONUM CUSPIDATUM; PROTEIN EXPRESSION; TAIWAN; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; CELL LINE; DOG; DRUG EFFECTS; INFLUENZA A VIRUS; METABOLISM; PHYSIOLOGY;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE; POLYGONUM CUSPIDATUM;

ANIMALS; CELL LINE; DOGS; FALLOPIA JAPONICA; HUMANS; INFLUENZA A VIRUS; INTERFERON-BETA; PLANT EXTRACTS; TOLL-LIKE RECEPTOR 9; VIRUS REPLICATION;

EID: 84922575717     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117602     Document Type: Article

References (32)

1. Nicholson KG, Wood JM, Zambon M (2003) Influenza. Lancet 362: 1733-1745. PMID: 14643124
2. Dawood FS, Jain S, Finelli L, Shaw MW, Lindstrom S, et al. (2009) Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 360: 2605-2615. doi: 10.1056/NEJMoa0903810 PMID: 19423869
3. Gao HN, Lu HZ, Cao B, Du B, Shang H, et al. (2013) Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med 368: 2277-2285. doi: 10.1056/NEJMoa1305584 PMID: 23697469
4. Jackson RJ, Cooper KL, Tappenden P, Rees A, Simpson EL, et al. (2011) Oseltamivir, zanamivir and amantadine in the prevention of influenza: a systematic review. J Infect 62: 14-25. doi: 10.1016/j.jinf. 2010.10.003 PMID: 20950645
5. van der Vries E, Schutten M, Fraaij P, Boucher C, Osterhaus A (2013) Influenza virus resistance to antiviral therapy. Adv Pharmacol 67: 217-246. doi: 10.1016/B978-0-12-405880-4.00006-8 PMID: 23886002
6. Dapat C, Kondo H, Dapat IC, Baranovich T, Suzuki Y, et al. (2013) Neuraminidase inhibitor susceptibility profile of pandemic and seasonal influenza viruses during the 2009-2010 and 2010-2011 influenza seasons in Japan. Antiviral Res 99: 261-269. doi: 10.1016/j.antiviral.2013.06.003 PMID: 23791870
7. Trost BM, Zhang T (2011) Development of a concise synthesis of (-)-oseltamivir (Tamiflu). Chemistry 17: 3630-3643. doi: 10.1002/chem.201003454 PMID: 21365707
8. Muhammad Nouman Sohail FR, Karim A, Kanwal U, Attitalla IH (2011) Plant as a Source of Natural Antiviral Agents. Asian Journal of Animal and Veterinary Advances 6: 1125-1152.
9. Park S, Kim JI, Lee I, Lee S, Hwang MW, et al. (2013) Aronia melanocarpa and its components demonstrate antiviral activity against influenza viruses. Biochem Biophys Res Commun 440: 14-19. doi: 10.1016/j.bbrc.2013.08.090 PMID: 24012672
10. Han JH, Koh W, Lee HJ, Lee EO, Lee SJ, et al. (2012) Analgesic and anti-inflammatory effects of ethyl acetate fraction of Polygonum cuspidatum in experimental animals. Immunopharmacol Immunotoxicol 34: 191-195. doi: 10.3109/08923973.2011.590499 PMID: 21711083
11. Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P, et al. (2010) An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol. J Clin Endocrinol Metab 95: E1-8. doi: 10.1210/jc.2010-0482 PMID: 20534755
12. Julia Khristine Aluyen QNT, Tran T, Yang AE, Gottlieb HB, Bellanger RA (2012) Resveratrol: Potential as Anticancer Agent. Journal of Dietary Supplements 9: 45-56. doi: 10.3109/19390211.2011.650842 PMID: 22432802
13. Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, et al. (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408: 740-745. PMID: 11130078
14. Krieg AM (2002) CpG motifs in bacterial DNA and their immune effects. Annual Review of Immunology 20: 709-760. PMID: 11861616
15. Hacker H, Vabulas RM, Takeuchi O, Hoshino K, Akira S, et al. (2000) Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. Journal of Experimental Medicine 192: 595-600. PMID: 10952730
16. Honda K, Yanai H, Negishi H, Asagiri M, Sato M, et al. (2005) IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-777. PMID: 15800576
17. Mamane Y, Heylbroeck C, Genin P, Algarte M, Servant MJ, et al. (1999) Interferon regulatory factors: the next generation. Gene 237: 1-14. PMID: 10524230
18. Biron CA (2001) Interferons alpha and beta as immune regulators-A new look. Immunity 14: 661-664 PMID: 11420036
19. Garcia-Sastre A, Egorov A, Matassov D, Brandt S, Levy DE, et al. (1998) Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. Virology 252: 324-330. PMID: 9878611
20. Lutz A, Dyall J, Olivo PD, Pekosz A (2005) Virus-inducible reporter genes as a tool for detecting and quantifying influenza A virus replication. Journal of Virological Methods 126: 13-20. PMID: 15847914
21. Naikhin AN, Donina SA, Petukhova GD, Koren'kov EM, Doroshenko EM, et al. (2013) [Humoral and cell-mediated immune responses in humans to the A/California/07/2009 (H1N1) virus, A(H1N1) pdm2009]. Vopr Virusol 58: 38-42. PMID: 24640170
22. Wiley DC, Skehel JJ (1987) The structure and function of the hemagglutinin membrane glycoprotein of influenza virus. Annu Rev Biochem 56: 365-394. PMID: 3304138
23. Gamblin SJ, Skehel JJ (2010) Influenza hemagglutinin and neuraminidase membrane glycoproteins. J Biol Chem 285: 28403-28409. doi: 10.1074/jbc.R110.129809 PMID: 20538598
24. Valarcher JF, Furze J, Wyld S, Cook R, Conzelmann KK, et al. (2003) Role of alpha/beta interferons in the attenuation and immunogenicity of recombinant bovine respiratory syncytial viruses lacking NS proteins. J Virol 77: 8426-8439. PMID: 12857912
25. Wang X, Li M, Zheng H, Muster T, Palese P, et al. (2000) Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. J Virol 74: 11566-11573. PMID: 11090154
26. Garcia-Sastre A, Biron CA (2006) Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312: 879-882. PMID: 16690858
27. Talon J, Horvath CM, Polley R, Basler CF, Muster T, et al. (2000) Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J Virol 74: 7989-7996. PMID: 10933707
28. Sato M, Tanaka N, Hata N, Oda E, Taniguchi T (1998) Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-beta gene. FEBS Lett 425: 112-116. PMID: 9541017
29. Schafer SL, Lin R, Moore PA, Hiscott J, Pitha PM (1998) Regulation of type I interferon gene expression by interferon regulatory factor-3. J Biol Chem 273: 2714-2720. PMID: 9446577
30. Opitz B, Rejaibi A, Dauber B, Eckhard J, Vinzing M, et al. (2007) IFN beta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein. Cellular Microbiology 9: 930-938. PMID: 17140406
31. Bonjardim CA, Ferreira PC, Kroon EG (2009) Interferons: signaling, antiviral and viral evasion. Immunol Lett 122: 1-11. doi: 10.1016/j.imlet.2008.11.002 PMID: 19059436
32. Honda K, Taniguchi T (2006) IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6: 644-658. PMID: 16932750