메뉴 건너뛰기




Volumn 10, Issue 2, 2015, Pages

Antrodin C inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via suppression of Smad2/3 and β-catenin signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords

ANTRODIN C; BETA CATENIN; GELATINASE A; GELATINASE B; MALEIMIDE DERIVATIVE; NERVE CELL ADHESION MOLECULE; OCCLUDIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UROKINASE; UVOMORULIN; VIMENTIN; ANTINEOPLASTIC AGENT; CADHERIN;

EID: 84922572428     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117111     Document Type: Article
Times cited : (43)

References (33)
  • 3
    • 84885915873 scopus 로고    scopus 로고
    • Epithelial-mesenchymal plasticity in carcinoma metastasis
    • PMID: 24142872
    • Tsai JH, Yang J (2013) Epithelial-mesenchymal plasticity in carcinoma metastasis. Genes Dev 27: 2192-2206. doi: 10.1101/gad.225334.113 PMID: 24142872
    • (2013) Genes Dev , vol.27 , pp. 2192-2206
    • Tsai, J.H.1    Yang, J.2
  • 4
    • 84055216938 scopus 로고    scopus 로고
    • Mechanism of the mesenchymal-epithelial transition and its relationship with metastatic tumor formation
    • PMID: 21840933
    • Yao D, Dai C, Peng S (2011) Mechanism of the mesenchymal-epithelial transition and its relationship with metastatic tumor formation. Mol Cancer Res 9: 1608-1620. doi: 10.1158/1541-7786.MCR-10-0568 PMID: 21840933
    • (2011) Mol Cancer Res , vol.9 , pp. 1608-1620
    • Yao, D.1    Dai, C.2    Peng, S.3
  • 5
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • PMID: 16493418
    • Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-142. PMID: 16493418
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 6
    • 33749367676 scopus 로고    scopus 로고
    • The met pathway: Master switch and drug target in cancer progression
    • PMID: 16873884
    • Mazzone M, Comoglio PM (2006) The Met pathway: master switch and drug target in cancer progression. FASEB J 20: 1611-1621. PMID: 16873884
    • (2006) FASEB J , vol.20 , pp. 1611-1621
    • Mazzone, M.1    Comoglio, P.M.2
  • 7
    • 84901782974 scopus 로고    scopus 로고
    • Two FACes of TGF-beta1 in breast cancer
    • PMID: 24891760
    • Zarzynska JM (2014) Two FACes of TGF-beta1 in breast cancer. Mediators Inflamm 2014: 141747. doi: 10.1155/2014/141747 PMID: 24891760
    • (2014) Mediators Inflamm , vol.2014 , pp. 141747
    • Zarzynska, J.M.1
  • 8
    • 84872852680 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 enhances the invasiveness of breast cancer cells by inducing a Smad2-dependent epithelial-to-mesenchymal transition
    • PMID: 23129177
    • Lv ZD, Kong B, Li JG, Qu HL, Wang XG, et al. (2013) Transforming growth factor-beta 1 enhances the invasiveness of breast cancer cells by inducing a Smad2-dependent epithelial-to-mesenchymal transition. Oncol Rep 29: 219-225. doi: 10.3892/or.2012.2111 PMID: 23129177
    • (2013) Oncol Rep , vol.29 , pp. 219-225
    • Lv, Z.D.1    Kong, B.2    Li, J.G.3    Qu, H.L.4    Wang, X.G.5
  • 9
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-beta signal transduction
    • PMID: 11792802
    • Moustakas A, Souchelnytskyi S, Heldin CH (2001) Smad regulation in TGF-beta signal transduction. J Cell Sci 114: 4359-4369. PMID: 11792802
    • (2001) J Cell Sci , vol.114 , pp. 4359-4369
    • Moustakas, A.1    Souchelnytskyi, S.2    Heldin, C.H.3
  • 10
    • 80052203143 scopus 로고    scopus 로고
    • TGF-beta/SMAD/GLI2 signaling axis in cancer progression and metastasis
    • PMID: 21862631
    • Javelaud D, Alexaki VI, Dennler S, Mohammad KS, Guise TA, et al. (2011) TGF-beta/SMAD/GLI2 signaling axis in cancer progression and metastasis. Cancer Res 71: 5606-5610. doi: 10.1158/0008-5472.CAN-11-1194 PMID: 21862631
    • (2011) Cancer Res , vol.71 , pp. 5606-5610
    • Javelaud, D.1    Alexaki, V.I.2    Dennler, S.3    Mohammad, K.S.4    Guise, T.A.5
  • 11
    • 33646576169 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tumor metastasis
    • PMID: 16680569
    • Deryugina EI, Quigley JP (2006) Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 25: 9-34. PMID: 16680569
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 9-34
    • Deryugina, E.I.1    Quigley, J.P.2
  • 12
    • 84893858450 scopus 로고    scopus 로고
    • Transforming growth factor-beta and matrix metalloproteinases: Functional interactions in tumor stroma-infiltrating myeloid cells
    • PMID: 24578639
    • Krstic J, Santibanez JF (2014) Transforming growth factor-beta and matrix metalloproteinases: functional interactions in tumor stroma-infiltrating myeloid cells. Scientific World Journal 2014: 521754. doi: 10.1155/2014/521754 PMID: 24578639
    • (2014) Scientific World Journal , vol.2014 , pp. 521754
    • Krstic, J.1    Santibanez, J.F.2
  • 13
    • 79960838436 scopus 로고    scopus 로고
    • The TGF-beta/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system
    • PMID: 20821046
    • Wiercinska E, Naber HP, Pardali E, van der Pluijm G, van Dam H, et al. (2011) The TGF-beta/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system. Breast Cancer Res Treat 128: 657-666. doi: 10.1007/s10549-010-1147-x PMID: 20821046
    • (2011) Breast Cancer Res Treat , vol.128 , pp. 657-666
    • Wiercinska, E.1    Naber, H.P.2    Pardali, E.3    Van Der-Pluijm, G.4    Van Dam, H.5
  • 14
    • 84875373539 scopus 로고    scopus 로고
    • The urokinase plasminogen activator system in breast cancer invasion and metastasis
    • PMID: 23201006
    • Tang L, Han X (2013) The urokinase plasminogen activator system in breast cancer invasion and metastasis. Biomed Pharmacother 67: 179-182. doi: 10.1016/j.biopha.2012.10.003 PMID: 23201006
    • (2013) Biomed Pharmacother , vol.67 , pp. 179-182
    • Tang, L.1    Han, X.2
  • 15
    • 82755176633 scopus 로고    scopus 로고
    • Regulation of breast cancer-induced bone lesions by beta-catenin protein signaling
    • PMID: 22009747
    • Chen Y, Shi HY, Stock SR, Stern PH, Zhang M (2011) Regulation of breast cancer-induced bone lesions by beta-catenin protein signaling. J Biol Chem 286: 42575-42584. doi: 10.1074/jbc.M111. 294595 PMID: 22009747
    • (2011) J Biol Chem , vol.286 , pp. 42575-42584
    • Chen, Y.1    Shi, H.Y.2    Stock, S.R.3    Stern, P.H.4    Zhang, M.5
  • 16
    • 73949093736 scopus 로고    scopus 로고
    • Regulation of Wnt/beta-catenin signaling by protein kinases
    • PMID: 19623618
    • Verheyen EM, Gottardi CJ (2010) Regulation of Wnt/beta-catenin signaling by protein kinases. Dev Dyn 239: 34-44. doi: 10.1002/dvdy.22019 PMID: 19623618
    • (2010) Dev Dyn , vol.239 , pp. 34-44
    • Verheyen, E.M.1    Gottardi, C.J.2
  • 17
    • 84862001767 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/beta-catenin signaling is enhanced in irradiated medulloblastoma cells
    • PMID: 22511755
    • Asuthkar S, Gondi CS, Nalla AK, Velpula KK, Gorantla B, et al. (2012) Urokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/beta-catenin signaling is enhanced in irradiated medulloblastoma cells. J Biol Chem 287: 20576-20589. doi: 10.1074/jbc.M112.348888 PMID: 22511755
    • (2012) J Biol Chem , vol.287 , pp. 20576-20589
    • Asuthkar, S.1    Gondi, C.S.2    Nalla, A.K.3    Velpula, K.K.4    Gorantla, B.5
  • 18
    • 84856410366 scopus 로고    scopus 로고
    • Subtype-specific alterations of the Wnt signaling pathway in breast cancer: Clinical and prognostic significance
    • PMID: 22026417
    • Mukherjee N, Bhattacharya N, Alam N, Roy A, Roychoudhury S, et al. (2012) Subtype-specific alterations of the Wnt signaling pathway in breast cancer: clinical and prognostic significance. Cancer Sci 103: 210-220. doi: 10.1111/j.1349-7006.2011.02131.x PMID: 22026417
    • (2012) Cancer Sci , vol.103 , pp. 210-220
    • Mukherjee, N.1    Bhattacharya, N.2    Alam, N.3    Roy, A.4    Roychoudhury, S.5
  • 19
    • 82755198488 scopus 로고    scopus 로고
    • Beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
    • PMID: 22080605
    • Sanchez-Tillo E, de Barrios O, Siles L, Cuatrecasas M, Castells A, et al. (2011) beta-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. Proc Natl Acad Sci U S A 108: 19204-19209. doi: 10.1073/pnas.1108977108 PMID: 22080605
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 19204-19209
    • Sanchez-Tillo, E.1    De Barrios, O.2    Siles, L.3    Cuatrecasas, M.4    Castells, A.5
  • 20
    • 79955391837 scopus 로고    scopus 로고
    • IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-beta1 resulting in epithelial to mesenchymal transition
    • PMID: 21535875
    • Walsh LA, Damjanovski S (2011) IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-beta1 resulting in epithelial to mesenchymal transition. Cell Commun Signal 9: 10. doi: 10.1186/1478-811X-9-10 PMID: 21535875
    • (2011) Cell Commun Signal , vol.9 , pp. 10
    • Walsh, L.A.1    Damjanovski, S.2
  • 21
    • 57949110602 scopus 로고    scopus 로고
    • Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases
    • PMID: 19061947
    • Ao ZH, Xu ZH, Lu ZM, Xu HY, Zhang XM, et al. (2009) Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases. J Ethnopharmacol 121: 194-212. doi: 10.1016/j.jep.2008.10.039 PMID: 19061947
    • (2009) J Ethnopharmacol , vol.121 , pp. 194-212
    • Ao, Z.H.1    Xu, Z.H.2    Lu, Z.M.3    Xu, H.Y.4    Zhang, X.M.5
  • 22
    • 84879412069 scopus 로고    scopus 로고
    • Recent research and development of Antrodia cinnamomea
    • PMID: 23563277
    • Lu MC, El-Shazly M, Wu TY, Du YC, Chang TT, et al. (2013) Recent research and development of Antrodia cinnamomea. Pharmacol Ther 139: 124-156. doi: 10.1016/j.pharmthera.2013.04.001 PMID: 23563277
    • (2013) Pharmacol Ther , vol.139 , pp. 124-156
    • Lu, M.C.1    El-Shazly, M.2    Wu, T.Y.3    Du, Y.C.4    Chang, T.T.5
  • 23
    • 0942269010 scopus 로고    scopus 로고
    • Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line
    • PMID: 14738384
    • Nakamura N, Hirakawa A, Gao JJ, Kakuda H, Shiro M, et al. (2004) Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line. J Nat Prod 67: 46-48. PMID: 14738384
    • (2004) J Nat Prod , vol.67 , pp. 46-48
    • Nakamura, N.1    Hirakawa, A.2    Gao, J.J.3    Kakuda, H.4    Shiro, M.5
  • 24
    • 49049098089 scopus 로고    scopus 로고
    • Maleimide and maleic anhydride derivatives from the mycelia of Antrodia cinnamomea and their nitric oxide inhibitory activities in macrophages
    • PMID: 18522430
    • Wu MD, Cheng MJ, Wang BC, Yech YJ, Lai JT, et al. (2008) Maleimide and maleic anhydride derivatives from the mycelia of Antrodia cinnamomea and their nitric oxide inhibitory activities in macrophages. J Nat Prod 71: 1258-1261. doi: 10.1021/np070634k PMID: 18522430
    • (2008) J Nat Prod , vol.71 , pp. 1258-1261
    • Wu, M.D.1    Cheng, M.J.2    Wang, B.C.3    Yech, Y.J.4    Lai, J.T.5
  • 25
    • 51649095163 scopus 로고    scopus 로고
    • Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata
    • PMID: 18642845
    • Chien SC, Chen ML, Kuo HT, Tsai YC, Lin BF, et al. (2008) Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata. J Agric Food Chem 56: 7017-7022. doi: 10.1021/jf801171x PMID: 18642845
    • (2008) J Agric Food Chem , vol.56 , pp. 7017-7022
    • Chien, S.C.1    Chen, M.L.2    Kuo, H.T.3    Tsai, Y.C.4    Lin, B.F.5
  • 26
    • 84875044136 scopus 로고    scopus 로고
    • Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors
    • PMID: 23516540
    • Zhang X, Li Y, Zhang Y, Song J, Wang Q, et al. (2013) Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors. PLoS One 8: e58719. doi: 10.1371/journal.pone.0058719 PMID: 23516540
    • (2013) PLoS One , vol.8 , pp. e58719
    • Zhang, X.1    Li, Y.2    Zhang, Y.3    Song, J.4    Wang, Q.5
  • 27
    • 0035864376 scopus 로고    scopus 로고
    • MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells
    • PMID: 11161720
    • Deryugina EI, Ratnikov B, Monosov E, Postnova TI, DiScipio R, et al. (2001) MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells. Exp Cell Res 263: 209-223. PMID: 11161720
    • (2001) Exp Cell Res , vol.263 , pp. 209-223
    • Deryugina, E.I.1    Ratnikov, B.2    Monosov, E.3    Postnova, T.I.4    Discipio, R.5
  • 28
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
    • PMID: 18539112
    • Yang J, Weinberg RA (2008) Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 14: 818-829. doi: 10.1016/j.devcel.2008.05.009 PMID: 18539112
    • (2008) Dev Cell , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 29
    • 2942564379 scopus 로고    scopus 로고
    • The actin cytoskeleton in normal and pathological cell motility
    • PMID: 15203104
    • Lambrechts A, Van Troys M, Ampe C (2004) The actin cytoskeleton in normal and pathological cell motility. Int J Biochem Cell Biol 36: 1890-1909. PMID: 15203104
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1890-1909
    • Lambrechts, A.1    Van Troys, M.2    Ampe, C.3
  • 30
    • 77950903213 scopus 로고    scopus 로고
    • Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells
    • PMID: 20308542
    • de Graauw M, van Miltenburg MH, Schmidt MK, Pont C, Lalai R, et al. (2010) Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells. Proc Natl Acad Sci U S A 107: 6340-6345. doi: 10.1073/pnas.0913360107 PMID: 20308542
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 6340-6345
    • De Graauw, M.1    Van Miltenburg, M.H.2    Schmidt, M.K.3    Pont, C.4    Lalai, R.5
  • 31
    • 84865059388 scopus 로고    scopus 로고
    • TGF-beta induces serous borderline ovarian tumor cell invasion by activating EMT but triggers apoptosis in low-grade serous ovarian carcinoma cells
    • PMID: 22905131
    • Cheng JC, Auersperg N, Leung PC (2012) TGF-beta induces serous borderline ovarian tumor cell invasion by activating EMT but triggers apoptosis in low-grade serous ovarian carcinoma cells. PLoS One 7: e42436. doi: 10.1371/journal.pone.0042436 PMID: 22905131
    • (2012) PLoS One , vol.7 , pp. e42436
    • Cheng, J.C.1    Auersperg, N.2    Leung, P.C.3
  • 32
    • 84881236485 scopus 로고    scopus 로고
    • Specific interactions between Smad proteins and AP-1 components determine TGFbeta-induced breast cancer cell invasion
    • PMID: 22926518
    • Sundqvist A, Zieba A, Vasilaki E, Herrera Hidalgo C, Soderberg O, et al. (2013) Specific interactions between Smad proteins and AP-1 components determine TGFbeta-induced breast cancer cell invasion. Oncogene 32: 3606-3615. doi: 10.1038/onc.2012.370 PMID: 22926518
    • (2013) Oncogene , vol.32 , pp. 3606-3615
    • Sundqvist, A.1    Zieba, A.2    Vasilaki, E.3    Herrera Hidalgo, C.4    Soderberg, O.5
  • 33
    • 43049175154 scopus 로고    scopus 로고
    • TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts
    • PMID: 18346908
    • Caraci F, Gili E, Calafiore M, Failla M, La Rosa C, et al. (2008) TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts. Pharmacol Res 57: 274-282. doi: 10.1016/j.phrs.2008.02.001 PMID: 18346908
    • (2008) Pharmacol Res , vol.57 , pp. 274-282
    • Caraci, F.1    Gili, E.2    Calafiore, M.3    Failla, M.4    La Rosa, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.