메뉴 건너뛰기




Volumn 44, Issue 12, 2014, Pages 1172-1180

Neoadjuvant gemcitabine-based accelerated hyperfractionation chemoradiotherapy for patients with borderline resectable pancreatic adenocarcinoma

Author keywords

Gemcitabine; Neoadjuvant; Pancreatic cancer

Indexed keywords

GEMCITABINE; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE;

EID: 84922538202     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hyu143     Document Type: Article
Times cited : (26)

References (36)
  • 1
    • 33748962008 scopus 로고    scopus 로고
    • Pancreatic resections after chemotherapy for locally advanced ductal adenocarcinoma: analysis of perioperative outcome and survival
    • Massuco P, Capussotti L, Magnino A, et al. Pancreatic resections after chemotherapy for locally advanced ductal adenocarcinoma: analysis of perioperative outcome and survival. Ann Surg Oncol 2006;13:1201-8.
    • (2006) Ann Surg Oncol , vol.13 , pp. 1201-1208
    • Massuco, P.1    Capussotti, L.2    Magnino, A.3
  • 2
    • 70249099504 scopus 로고    scopus 로고
    • A randomised phase III trial comparing gemcitabine with surgery-only in patients with resected pancreatic cancer: Japanese Study Group of Adjuvant Therapy for Pancreatic Cancer
    • Ueno H, Kosuge T, Matsuyama Y, et al. A randomised phase III trial comparing gemcitabine with surgery-only in patients with resected pancreatic cancer: Japanese Study Group of Adjuvant Therapy for Pancreatic Cancer. Br J Cancer 2009;101:908-15.
    • (2009) Br J Cancer , vol.101 , pp. 908-915
    • Ueno, H.1    Kosuge, T.2    Matsuyama, Y.3
  • 3
    • 33846405332 scopus 로고    scopus 로고
    • Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial
    • Oettle H, Post S, Neuhaus P, et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. JAMA 2007;297:267-77.
    • (2007) JAMA , vol.297 , pp. 267-277
    • Oettle, H.1    Post, S.2    Neuhaus, P.3
  • 4
    • 18244369036 scopus 로고    scopus 로고
    • Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas
    • White RR, Hurwitz HI, Morse MA, et al. Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas. Ann Sur Oncol 2001;8:758-65.
    • (2001) Ann Sur Oncol , vol.8 , pp. 758-765
    • White, R.R.1    Hurwitz, H.I.2    Morse, M.A.3
  • 5
    • 33748445708 scopus 로고    scopus 로고
    • Randomized Phase III trial of gemcitabine plus cisplatin compared with gemcitabine alone in advanced pancreatic cancer
    • Heinemann V, Quietzsch D, Gieseler F, et al. Randomized Phase III trial of gemcitabine plus cisplatin compared with gemcitabine alone in advanced pancreatic cancer. J Clin Oncol 2006;24:3946-52.
    • (2006) J Clin Oncol , vol.24 , pp. 3946-3952
    • Heinemann, V.1    Quietzsch, D.2    Gieseler, F.3
  • 6
    • 0036682041 scopus 로고    scopus 로고
    • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
    • Berlin JD, Catalano P, Thomas JP, Kugler JW, Haller DG, Benson AB, 3rd. Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol 2002;20:3270-5.
    • (2002) J Clin Oncol , vol.20 , pp. 3270-3275
    • Berlin, J.D.1    Catalano, P.2    Thomas, J.P.3    Kugler, J.W.4    Haller, D.G.5    Benson 3rd, A.B.6
  • 7
    • 0141688333 scopus 로고    scopus 로고
    • Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore MJ, Hamm J, Dancey J, et al. Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2003;21:3296-302.
    • (2003) J Clin Oncol , vol.21 , pp. 3296-3302
    • Moore, M.J.1    Hamm, J.2    Dancey, J.3
  • 8
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • Rocha LCM, Green MR, Roche R, et al. Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 2004;22:3776-83.
    • (2004) J Clin Oncol , vol.22 , pp. 3776-3783
    • Rocha, L.C.M.1    Green, M.R.2    Roche, R.3
  • 9
    • 0037100983 scopus 로고    scopus 로고
    • A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
    • Bramhall SR, Schultz J, Nemunaitis J, Brown PD, BailletM, Buckels JA. A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer. Br J Cancer 2002;87:161-7.
    • (2002) Br J Cancer , vol.87 , pp. 161-167
    • Bramhall, S.R.1    Schultz, J.2    Nemunaitis, J.3    Brown, P.D.4    Baillet, M.5    Buckels, J.A.6
  • 10
    • 0035424135 scopus 로고    scopus 로고
    • Marimastat Pancreatic Cancer Study Group. Marimastat as first-line therapy for patients with unresectable pancreatic cancer: a randomized trial
    • 3477-3455
    • Bramhal SR, Rosemurgy A, Brown PD, Bowry C, Buckels JA. Marimastat Pancreatic Cancer Study Group. Marimastat as first-line therapy for patients with unresectable pancreatic cancer: a randomized trial. J Clin Oncol 2001;19:3477-55.
    • (2001) J Clin Oncol , vol.19
    • Bramhal, S.R.1    Rosemurgy, A.2    Brown, P.D.3    Bowry, C.4    Buckels, J.A.5
  • 11
    • 2342645506 scopus 로고    scopus 로고
    • Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer
    • Van Cutsem E, van de Velde H, Karase P, et al. Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer. J Clin Oncol 2004;22:1430-8.
    • (2004) J Clin Oncol , vol.22 , pp. 1430-1438
    • Van Cutsem, E.1    van de Velde, H.2    Karase, P.3
  • 12
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial
    • Burris HA, Moore MJ, Anderson J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-13.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Anderson, J.3
  • 13
    • 40449113435 scopus 로고    scopus 로고
    • Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial
    • Regine WF, Winter KA, Abrams RA, et al. Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial. JAMA 2008;299:1019-26.
    • (2008) JAMA , vol.299 , pp. 1019-1026
    • Regine, W.F.1    Winter, K.A.2    Abrams, R.A.3
  • 14
    • 77956416112 scopus 로고    scopus 로고
    • Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial
    • Neoptolemos JP, Stocken DD, Bassi C, et al. Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial. JAMA 2010;304:1073-81.
    • (2010) JAMA , vol.304 , pp. 1073-1081
    • Neoptolemos, J.P.1    Stocken, D.D.2    Bassi, C.3
  • 15
    • 3242713145 scopus 로고    scopus 로고
    • Classification of surgical complications A new proposal with evaluation in a cohort of 6336 patients and results of a survey
    • Dindo D, Demartines D, Clavien PA. Classification of surgical complications A new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 2004;240:205-13.
    • (2004) Ann Surg , vol.240 , pp. 205-213
    • Dindo, D.1    Demartines, D.2    Clavien, P.A.3
  • 16
    • 0026454511 scopus 로고
    • Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas
    • Evans DB, Rich TA, Byrd DR, et al. Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas. Arch Surg 1992;127:1335-9.
    • (1992) Arch Surg , vol.127 , pp. 1335-1339
    • Evans, D.B.1    Rich, T.A.2    Byrd, D.R.3
  • 17
    • 0019410935 scopus 로고
    • Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group
    • Moertel CG, Frytak S, Hahn RG, et al. Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group. Cancer 1981;48:1705-10.
    • (1981) Cancer , vol.48 , pp. 1705-1710
    • Moertel, C.G.1    Frytak, S.2    Hahn, R.G.3
  • 18
    • 0023722682 scopus 로고
    • Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone
    • Gastrointestinal Tumor Study Group. Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. J Natl Cancer Inst 1988;80:751-5.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 751-755
  • 19
    • 0032421150 scopus 로고    scopus 로고
    • Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for resectable pancreatic adenocarcinoma
    • Pisters PW, Abbruzzese JL, Janjan NA, et al. Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for resectable pancreatic adenocarcinoma. J Clin Oncol. 1998;16:3843-50.
    • (1998) J Clin Oncol. , vol.16 , pp. 3843-3850
    • Pisters, P.W.1    Abbruzzese, J.L.2    Janjan, N.A.3
  • 20
    • 0037092960 scopus 로고    scopus 로고
    • Preoperative paclitaxel and concurrent rapid fractionation radiation for resectable pancreatic adenocarcinoma: toxicities, histologic response rates, and event-free outcome
    • Pisters PW, Wolff RA, Janjan NA, et al. Preoperative paclitaxel and concurrent rapid fractionation radiation for resectable pancreatic adenocarcinoma: toxicities, histologic response rates, and event-free outcome. J Clin Oncol 2002;20:2537-44.
    • (2002) J Clin Oncol , vol.20 , pp. 2537-2544
    • Pisters, P.W.1    Wolff, R.A.2    Janjan, N.A.3
  • 21
    • 0026441565 scopus 로고
    • Difluorodeoxycytidine (dFDC)-gemcitabine: a phase I study
    • Poplin EA, Corbett T, Flaherty L, et al. Difluorodeoxycytidine (dFDC)-gemcitabine: a phase I study. Invest New Drugs 1992;10:165-70.
    • (1992) Invest New Drugs , vol.10 , pp. 165-170
    • Poplin, E.A.1    Corbett, T.2    Flaherty, L.3
  • 22
    • 8944261362 scopus 로고    scopus 로고
    • A phase II trial of gemcitabine in patients with 5-FU refractory pancreas cancer
    • Rothenberg M, Moore M, Cripps M, et al. A phase II trial of gemcitabine in patients with 5-FU refractory pancreas cancer. Ann Oncol 1996;7:347-53.
    • (1996) Ann Oncol , vol.7 , pp. 347-353
    • Rothenberg, M.1    Moore, M.2    Cripps, M.3
  • 25
    • 0000046403 scopus 로고    scopus 로고
    • A phase I study of gemcitabine in combination with radiation therapy in patients with localized, unresectable pancreatic cancer
    • McGinn C, Smith D, Ozark's C, et al. A phase I study of gemcitabine in combination with radiation therapy in patients with localized, unresectable pancreatic cancer. Proc ASCO 1998;17:264a.
    • (1998) Proc ASCO , vol.17 , pp. 264a
    • McGinn, C.1    Smith, D.2    Ozark's, C.3
  • 26
    • 0035890443 scopus 로고    scopus 로고
    • Phase I trial of radiation dose escalation with concurrent weekly full-dose gemcitabine in patients with advanced pancreatic cancer
    • McGinn C, Zalupski M, Shureiqi I, et al. Phase I trial of radiation dose escalation with concurrent weekly full-dose gemcitabine in patients with advanced pancreatic cancer. J Clin Oncol 2001;19:4202-8.
    • (2001) J Clin Oncol , vol.19 , pp. 4202-4208
    • McGinn, C.1    Zalupski, M.2    Shureiqi, I.3
  • 27
    • 0035253713 scopus 로고    scopus 로고
    • Radiation concurrent with gemcitabine for locally advanced head and neck cancer: a phase I trial and intracellular drug incorporation study
    • Eisbruch A, Shewach DS, Bradford CR, et al. Radiation concurrent with gemcitabine for locally advanced head and neck cancer: a phase I trial and intracellular drug incorporation study. J Clin Oncol 2001;19:792-9.
    • (2001) J Clin Oncol , vol.19 , pp. 792-799
    • Eisbruch, A.1    Shewach, D.S.2    Bradford, C.R.3
  • 28
    • 84922507678 scopus 로고    scopus 로고
    • Progress in radiation therapy by hyperfractionation
    • Nishimura Y, Hiraoka M. Progress in radiation therapy by hyperfractionation. J Radiat Res 1997;38:272.
    • (1997) J Radiat Res , vol.38 , pp. 272
    • Nishimura, Y.1    Hiraoka, M.2
  • 29
    • 0034880820 scopus 로고    scopus 로고
    • Phase I trial of gemcitabine combined with radiation for the treatment of locally advanced pancreatic adenocarcinoma
    • Wolff RA, Evans DB, Gravel DM, et al. Phase I trial of gemcitabine combined with radiation for the treatment of locally advanced pancreatic adenocarcinoma. Clin Cancer Res 2001;7:2246-53.
    • (2001) Clin Cancer Res , vol.7 , pp. 2246-2253
    • Wolff, R.A.1    Evans, D.B.2    Gravel, D.M.3
  • 30
    • 31544438080 scopus 로고    scopus 로고
    • A multi-institutional phase II trial of preoperative full-dose gemcitabine and concurrent radiation for patients with potentially resectable pancreatic carcinoma
    • Talamonti MS, Small W, Jr, Mulcahy MF, et al. A multi-institutional phase II trial of preoperative full-dose gemcitabine and concurrent radiation for patients with potentially resectable pancreatic carcinoma. Ann Surg Oncol 2006;13:150-8.
    • (2006) Ann Surg Oncol , vol.13 , pp. 150-158
    • Talamonti, M.S.1    Small, W.2    Mulcahy, M.F.3
  • 31
    • 84897082482 scopus 로고    scopus 로고
    • Influence of preoperative anti-cancer therapy on resectability and perioperative outcomes in patients with pancreatic cancer: project study by the Japanese Society of Hepato-Biliary-Pancreatic Surgery
    • Motoi F, Unno M, Takahashi H, et al. Influence of preoperative anti-cancer therapy on resectability and perioperative outcomes in patients with pancreatic cancer: project study by the Japanese Society of Hepato-Biliary-Pancreatic Surgery. J Hepatobiliary Pancreat Sci 2014;21:148-58.
    • (2014) J Hepatobiliary Pancreat Sci , vol.21 , pp. 148-158
    • Motoi, F.1    Unno, M.2    Takahashi, H.3
  • 32
    • 68249109951 scopus 로고    scopus 로고
    • Feasibility and efficacy of combination therapy with preoperative full-dose gemcitabine, concurrent three-dimensional conformal radiation, surgery, and postoperative liver perfusion chemotherapy for T3-pancreatic cancer
    • Ohigashi H, Ishikawa O, Eguchi H, et al. Feasibility and efficacy of combination therapy with preoperative full-dose gemcitabine, concurrent three-dimensional conformal radiation, surgery, and postoperative liver perfusion chemotherapy for T3-pancreatic cancer. Ann Surg 2009;250:88-95.
    • (2009) Ann Surg , vol.250 , pp. 88-95
    • Ohigashi, H.1    Ishikawa, O.2    Eguchi, H.3
  • 33
    • 77951709577 scopus 로고    scopus 로고
    • Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages
    • Gillen S, Schuster T, Meyer ZBC, et al. Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages. PLoS Med 2010;7:e1000267.
    • (2010) PLoS Med , vol.7
    • Gillen, S.1    Schuster, T.2    Meyer, ZBC.3
  • 34
    • 80052293264 scopus 로고    scopus 로고
    • Neoadjuvant therapy in pancreatic adenocarcinoma: a meta-analysis of phase II trials
    • Assifi MM, Lu X, Eibl G, et al. Neoadjuvant therapy in pancreatic adenocarcinoma: a meta-analysis of phase II trials. Surgery 2011;150:466-73.
    • (2011) Surgery , vol.150 , pp. 466-473
    • Assifi, M.M.1    Lu, X.2    Eibl, G.3
  • 35
    • 84862560790 scopus 로고    scopus 로고
    • Neoadjuvant/preoperative gemcitabine for patients with localized pancreatic cancer: a meta-analysis of prospective studies
    • Andriulli A, Festa V, Botteri E, et al. Neoadjuvant/preoperative gemcitabine for patients with localized pancreatic cancer: a meta-analysis of prospective studies. Ann Surg Oncol 2012;19:1644-62.
    • (2012) Ann Surg Oncol , vol.19 , pp. 1644-1662
    • Andriulli, A.1    Festa, V.2    Botteri, E.3
  • 36
    • 84887462960 scopus 로고    scopus 로고
    • Neoadjuvant chemo-radiotherapy for patients with borderline resectable pancreatic cancer: a metaanalytical evaluation of prospective studies
    • Festa V, Andriulli A, Rosaria M, et al. Neoadjuvant chemo-radiotherapy for patients with borderline resectable pancreatic cancer: a metaanalytical evaluation of prospective studies. J Pancreas (Online) 2013;14:618-25.
    • (2013) J Pancreas (Online) , vol.14 , pp. 618-625
    • Festa, V.1    Andriulli, A.2    Rosaria, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.