Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior

Brain Structure and Function

Volumn 221, Issue 3, 2016, Pages 1681-1689

  Stefanik, Michael T ^a,b   Kupchik, Yonatan M ^a,c   Kalivas, Peter W ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Archaerhodopsin; Cocaine seeking; Dendritic spines; Nucleus accumbens; Optogenetic; Prelimbic prefrontal cortex; Reinstatement

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; ARCHAERHODOPSIN; COCAINE; GLASS FIBER; N METHYL DEXTRO ASPARTIC ACID; OPSIN; RHODOPSIN; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS 2; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSOCIATION; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DENDRITIC SPINE; DRUG SEEKING BEHAVIOR; GENE SILENCING; GLUTAMATERGIC SYNAPSE; MALE; MICROINJECTION; NERVE CELL PLASTICITY; NONHUMAN; NUCLEUS ACCUMBENS CORE; OPTOGENETICS; PRELIMBIC CORTEX; PRIORITY JOURNAL; RAT; SYNAPTIC POTENTIAL; TRANSIENT SYNAPTIC POTENTIATION; ANIMAL; CYTOLOGY; DRUG EFFECTS; DRUG SELF ADMINISTRATION; EXCITATORY POSTSYNAPTIC POTENTIAL; INSTRUMENTAL CONDITIONING; NERVE CELL; NUCLEUS ACCUMBENS; PHYSIOLOGY; PREFRONTAL CORTEX; SENSORY NERVE; SPRAGUE DAWLEY RAT;

AFFERENT PATHWAYS; ANIMALS; COCAINE; CONDITIONING, OPERANT; CUES; DENDRITIC SPINES; DRUG-SEEKING BEHAVIOR; EXCITATORY POSTSYNAPTIC POTENTIALS; MALE; NEURONS; NUCLEUS ACCUMBENS; OPTOGENETICS; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; SELF ADMINISTRATION;

EID: 84922469561     PISSN: 18632653     EISSN: 18632661     Source Type: Journal    
DOI: 10.1007/s00429-015-0997-8     Document Type: Article

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